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Results: 1 to 20 of 86

1.

Hcrtr1 and 2 signaling differentially regulates depression-like behaviors.

Scott MM, Marcus JN, Pettersen A, Birnbaum SG, Mochizuki T, Scammell TE, Nestler EJ, Elmquist JK, Lutter M.

Behav Brain Res. 2011 Sep 23;222(2):289-94. doi: 10.1016/j.bbr.2011.02.044. Epub 2011 Mar 4.

PMID:
21377495
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Nicotine self-administration in the rat: effects of hypocretin antagonists and changes in hypocretin mRNA.

LeSage MG, Perry JL, Kotz CM, Shelley D, Corrigall WA.

Psychopharmacology (Berl). 2010 Apr;209(2):203-12. doi: 10.1007/s00213-010-1792-0. Epub 2010 Feb 24.

PMID:
20177882
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Orexin-1 receptor antagonism fails to reduce anxiety-like behaviour in either plus-maze-naïve or plus-maze-experienced mice.

Rodgers RJ, Wright FL, Snow NF, Taylor LJ.

Behav Brain Res. 2013 Apr 15;243:213-9. doi: 10.1016/j.bbr.2012.12.064. Epub 2013 Jan 17.

PMID:
23333844
[PubMed - indexed for MEDLINE]
4.

Genetic inactivation of the NMDA receptor NR2A subunit has anxiolytic- and antidepressant-like effects in mice.

Boyce-Rustay JM, Holmes A.

Neuropsychopharmacology. 2006 Nov;31(11):2405-14. Epub 2006 Feb 8.

PMID:
16482087
[PubMed - indexed for MEDLINE]
Free Article
5.

Dual hypocretin receptor antagonism is more effective for sleep promotion than antagonism of either receptor alone.

Morairty SR, Revel FG, Malherbe P, Moreau JL, Valladao D, Wettstein JG, Kilduff TS, Borroni E.

PLoS One. 2012;7(7):e39131. doi: 10.1371/journal.pone.0039131. Epub 2012 Jul 2.

PMID:
22768296
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

The selective orexin 1 receptor antagonist SB-334867-A impairs acquisition and consolidation but not retrieval of spatial memory in Morris water maze.

Akbari E, Naghdi N, Motamedi F.

Peptides. 2007 Mar;28(3):650-6. Epub 2006 Dec 11.

PMID:
17161886
[PubMed - indexed for MEDLINE]
7.

Genetic and pharmacological evidence of a role for GABA(B) receptors in the modulation of anxiety- and antidepressant-like behavior.

Mombereau C, Kaupmann K, Froestl W, Sansig G, van der Putten H, Cryan JF.

Neuropsychopharmacology. 2004 Jun;29(6):1050-62.

PMID:
15039762
[PubMed - indexed for MEDLINE]
Free Article
8.

Elevated anxiety-like and depressive behavior in Desert hedgehog knockout male mice.

Umehara F, Mishima K, Egashira N, Ogata A, Iwasaki K, Fujiwara M.

Behav Brain Res. 2006 Nov 1;174(1):167-73. Epub 2006 Sep 6.

PMID:
16952407
[PubMed - indexed for MEDLINE]
9.

Hypocretin receptor expression in canine and murine narcolepsy models and in hypocretin-ligand deficient human narcolepsy.

Mishima K, Fujiki N, Yoshida Y, Sakurai T, Honda M, Mignot E, Nishino S.

Sleep. 2008 Aug;31(8):1119-26.

PMID:
18714784
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Hypocretin/orexin signaling in the hypothalamic paraventricular nucleus is essential for the expression of nicotine withdrawal.

Plaza-Zabala A, Flores Á, Maldonado R, Berrendero F.

Biol Psychiatry. 2012 Feb 1;71(3):214-23. doi: 10.1016/j.biopsych.2011.06.025. Epub 2011 Aug 10.

PMID:
21831361
[PubMed - indexed for MEDLINE]
11.

Behavioral profile of P2X7 receptor knockout mice in animal models of depression and anxiety: relevance for neuropsychiatric disorders.

Basso AM, Bratcher NA, Harris RR, Jarvis MF, Decker MW, Rueter LE.

Behav Brain Res. 2009 Mar 2;198(1):83-90. doi: 10.1016/j.bbr.2008.10.018. Epub 2008 Oct 18.

PMID:
18996151
[PubMed - indexed for MEDLINE]
12.

Anti-depressant and anxiolytic like behaviors in PKCI/HINT1 knockout mice associated with elevated plasma corticosterone level.

Barbier E, Wang JB.

BMC Neurosci. 2009 Nov 13;10:132. doi: 10.1186/1471-2202-10-132.

PMID:
19912621
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

TNFalpha signaling in depression and anxiety: behavioral consequences of individual receptor targeting.

Simen BB, Duman CH, Simen AA, Duman RS.

Biol Psychiatry. 2006 May 1;59(9):775-85. Epub 2006 Feb 3.

PMID:
16458261
[PubMed - indexed for MEDLINE]
14.

Orexin / hypocretin 1 receptor antagonist reduces heroin self-administration and cue-induced heroin seeking.

Smith RJ, Aston-Jones G.

Eur J Neurosci. 2012 Mar;35(5):798-804. doi: 10.1111/j.1460-9568.2012.08013.x. Epub 2012 Feb 22.

PMID:
22356621
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Increased novelty-induced motor activity and reduced depression-like behavior in neuropeptide Y (NPY)-Y4 receptor knockout mice.

Tasan RO, Lin S, Hetzenauer A, Singewald N, Herzog H, Sperk G.

Neuroscience. 2009 Feb 18;158(4):1717-30. doi: 10.1016/j.neuroscience.2008.11.048. Epub 2008 Dec 9.

PMID:
19121371
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

GPR26-deficient mice display increased anxiety- and depression-like behaviors accompanied by reduced phosphorylated cyclic AMP responsive element-binding protein level in central amygdala.

Zhang LL, Wang JJ, Liu Y, Lu XB, Kuang Y, Wan YH, Chen Y, Yan HM, Fei J, Wang ZG.

Neuroscience. 2011 Nov 24;196:203-14. doi: 10.1016/j.neuroscience.2011.08.069. Epub 2011 Sep 8.

PMID:
21924326
[PubMed - indexed for MEDLINE]
17.

I.c.v. administration of orexin-A induces an antidepressive-like effect through hippocampal cell proliferation.

Ito N, Yabe T, Gamo Y, Nagai T, Oikawa T, Yamada H, Hanawa T.

Neuroscience. 2008 Dec 10;157(4):720-32. doi: 10.1016/j.neuroscience.2008.09.042. Epub 2008 Oct 1.

PMID:
18952152
[PubMed - indexed for MEDLINE]
18.

Activation of the orexin 1 receptor is a critical component of CO2-mediated anxiety and hypertension but not bradycardia.

Johnson PL, Samuels BC, Fitz SD, Lightman SL, Lowry CA, Shekhar A.

Neuropsychopharmacology. 2012 Jul;37(8):1911-22. doi: 10.1038/npp.2012.38. Epub 2012 Mar 28.

PMID:
22453138
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Depressive behavior and activation of the orexin/hypocretin system.

Arendt DH, Ronan PJ, Oliver KD, Callahan LB, Summers TR, Summers CH.

Behav Neurosci. 2013 Feb;127(1):86-94. doi: 10.1037/a0031442.

PMID:
23398442
[PubMed - indexed for MEDLINE]
20.

Antagonism of orexin 1 receptors eliminates motor hyperactivity and improves homing response acquisition in juvenile rats exposed to alcohol during early postnatal period.

Stettner GM, Kubin L, Volgin DV.

Behav Brain Res. 2011 Aug 1;221(1):324-8. doi: 10.1016/j.bbr.2011.03.028. Epub 2011 Mar 21.

PMID:
21420437
[PubMed - indexed for MEDLINE]
Free PMC Article

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