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Items: 1 to 20 of 113

1.

Targeting the activin type IIB receptor to improve muscle mass and function in the mdx mouse model of Duchenne muscular dystrophy.

Pistilli EE, Bogdanovich S, Goncalves MD, Ahima RS, Lachey J, Seehra J, Khurana T.

Am J Pathol. 2011 Mar;178(3):1287-97. doi: 10.1016/j.ajpath.2010.11.071.

2.

Pretreatment with a soluble activin type IIB receptor/Fc fusion protein improves hypoxia-induced muscle dysfunction.

Pistilli EE, Bogdanovich S, Mosqueira M, Lachey J, Seehra J, Khurana TS.

Am J Physiol Regul Integr Comp Physiol. 2010 Jan;298(1):R96-R103. doi: 10.1152/ajpregu.00138.2009. Epub 2009 Oct 28.

3.

Combined effect of AAV-U7-induced dystrophin exon skipping and soluble activin Type IIB receptor in mdx mice.

Hoogaars WM, Mouisel E, Pasternack A, Hulmi JJ, Relizani K, Schuelke M, Schirwis E, Garcia L, Ritvos O, Ferry A, 't Hoen PA, Amthor H.

Hum Gene Ther. 2012 Dec;23(12):1269-79. doi: 10.1089/hum.2012.056. Epub 2012 Sep 24.

PMID:
22894762
4.

Activin IIB receptor blockade attenuates dystrophic pathology in a mouse model of Duchenne muscular dystrophy.

Morine KJ, Bish LT, Selsby JT, Gazzara JA, Pendrak K, Sleeper MM, Barton ER, Lee SJ, Sweeney HL.

Muscle Nerve. 2010 Nov;42(5):722-30. doi: 10.1002/mus.21743.

5.

Exercise restores decreased physical activity levels and increases markers of autophagy and oxidative capacity in myostatin/activin-blocked mdx mice.

Hulmi JJ, Oliveira BM, Silvennoinen M, Hoogaars WM, Pasternack A, Kainulainen H, Ritvos O.

Am J Physiol Endocrinol Metab. 2013 Jul 15;305(2):E171-82. doi: 10.1152/ajpendo.00065.2013. Epub 2013 May 21.

6.

Functional improvement of dystrophic muscle by myostatin blockade.

Bogdanovich S, Krag TO, Barton ER, Morris LD, Whittemore LA, Ahima RS, Khurana TS.

Nature. 2002 Nov 28;420(6914):418-21.

PMID:
12459784
7.

Soluble activin receptor type IIB increases forward pulling tension in the mdx mouse.

George Carlson C, Bruemmer K, Sesti J, Stefanski C, Curtis H, Ucran J, Lachey J, Seehra JS.

Muscle Nerve. 2011 May;43(5):694-9. doi: 10.1002/mus.21944. Epub 2011 Apr 1.

8.

Myotonic ADR-MDX mutant mice show less severe muscular dystrophy than MDX mice.

Krämer R, Lochmüller H, Abicht A, Rüdel R, Brinkmeier H.

Neuromuscul Disord. 1998 Dec;8(8):542-50.

PMID:
10093060
9.
10.
11.

Interference with myostatin/ActRIIB signaling as a therapeutic strategy for Duchenne muscular dystrophy.

Amthor H, Hoogaars WM.

Curr Gene Ther. 2012 Jun;12(3):245-59. Review.

PMID:
22554312
12.

Effects of aging and voluntary exercise on the function of dystrophic muscle from mdx mice.

Wineinger MA, Abresch RT, Walsh SA, Carter GT.

Am J Phys Med Rehabil. 1998 Jan-Feb;77(1):20-7.

PMID:
9482375
13.

GLPG0492, a novel selective androgen receptor modulator, improves muscle performance in the exercised-mdx mouse model of muscular dystrophy.

Cozzoli A, Capogrosso RF, Sblendorio VT, Dinardo MM, Jagerschmidt C, Namour F, Camerino GM, De Luca A.

Pharmacol Res. 2013 Jun;72:9-24. doi: 10.1016/j.phrs.2013.03.003. Epub 2013 Mar 22.

PMID:
23523664
14.

mdx(⁵cv) mice manifest more severe muscle dysfunction and diaphragm force deficits than do mdx Mice.

Beastrom N, Lu H, Macke A, Canan BD, Johnson EK, Penton CM, Kaspar BK, Rodino-Klapac LR, Zhou L, Janssen PM, Montanaro F.

Am J Pathol. 2011 Nov;179(5):2464-74. doi: 10.1016/j.ajpath.2011.07.009. Epub 2011 Sep 3.

15.
16.

Gender differences in contractile and passive properties of mdx extensor digitorum longus muscle.

Hakim CH, Duan D.

Muscle Nerve. 2012 Feb;45(2):250-6. doi: 10.1002/mus.22275.

17.

Expression of the dystrophin isoform Dp116 preserves functional muscle mass and extends lifespan without preventing dystrophy in severely dystrophic mice.

Judge LM, Arnett AL, Banks GB, Chamberlain JS.

Hum Mol Genet. 2011 Dec 15;20(24):4978-90. doi: 10.1093/hmg/ddr433. Epub 2011 Sep 23.

18.

Covert persistence of mdx mouse myopathy is revealed by acute and chronic effects of irradiation.

Pagel CN, Partridge TA.

J Neurol Sci. 1999 Apr 1;164(2):103-16.

PMID:
10402020
19.

Enhanced expression of the alpha 7 beta 1 integrin reduces muscular dystrophy and restores viability in dystrophic mice.

Burkin DJ, Wallace GQ, Nicol KJ, Kaufman DJ, Kaufman SJ.

J Cell Biol. 2001 Mar 19;152(6):1207-18.

20.

Increased muscle force production and bone mineral density in ActRIIB-Fc-treated mature rodents.

Chiu CS, Peekhaus N, Weber H, Adamski S, Murray EM, Zhang HZ, Zhao JZ, Ernst R, Lineberger J, Huang L, Hampton R, Arnold BA, Vitelli S, Hamuro L, Wang WR, Wei N, Dillon GM, Miao J, Alves SE, Glantschnig H, Wang F, Wilkinson HA.

J Gerontol A Biol Sci Med Sci. 2013 Oct;68(10):1181-92. doi: 10.1093/gerona/glt030. Epub 2013 Mar 22.

PMID:
23525481
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