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Results: 1 to 20 of 80

1.

Polygenic modeling of genome-wide association studies: an application to prostate and breast cancer.

Witte JS, Hoffmann TJ.

OMICS. 2011 Jun;15(6):393-8. doi: 10.1089/omi.2010.0090. Epub 2011 Feb 24.

PMID:
21348634
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

A risk prediction algorithm based on family history and common genetic variants: application to prostate cancer with potential clinical impact.

Macinnis RJ, Antoniou AC, Eeles RA, Severi G, Al Olama AA, McGuffog L, Kote-Jarai Z, Guy M, O'Brien LT, Hall AL, Wilkinson RA, Sawyer E, Ardern-Jones AT, Dearnaley DP, Horwich A, Khoo VS, Parker CC, Huddart RA, Van As N, McCredie MR, English DR, Giles GG, Hopper JL, Easton DF.

Genet Epidemiol. 2011 Sep;35(6):549-56. doi: 10.1002/gepi.20605. Epub 2011 Jul 18.

PMID:
21769933
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Recent methods for polygenic analysis of genome-wide data implicate an important effect of common variants on cardiovascular disease risk.

Simonson MA, Wills AG, Keller MC, McQueen MB.

BMC Med Genet. 2011 Oct 26;12:146. doi: 10.1186/1471-2350-12-146.

PMID:
22029572
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Evaluation of polygenic risk scores for predicting breast and prostate cancer risk.

Machiela MJ, Chen CY, Chen C, Chanock SJ, Hunter DJ, Kraft P.

Genet Epidemiol. 2011 Sep;35(6):506-14. doi: 10.1002/gepi.20600. Epub 2011 May 26.

PMID:
21618606
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Estimation of effect size distribution from genome-wide association studies and implications for future discoveries.

Park JH, Wacholder S, Gail MH, Peters U, Jacobs KB, Chanock SJ, Chatterjee N.

Nat Genet. 2010 Jul;42(7):570-5. doi: 10.1038/ng.610. Epub 2010 Jun 20.

PMID:
20562874
[PubMed - indexed for MEDLINE]
6.

A systematic review of replication studies of prostate cancer susceptibility genetic variants in high-risk men originally identified from genome-wide association studies.

Ishak MB, Giri VN.

Cancer Epidemiol Biomarkers Prev. 2011 Aug;20(8):1599-610. doi: 10.1158/1055-9965.EPI-11-0312. Epub 2011 Jun 29. Review.

PMID:
21715604
[PubMed - indexed for MEDLINE]
Free Article
7.

Genomic inflation factors under polygenic inheritance.

Yang J, Weedon MN, Purcell S, Lettre G, Estrada K, Willer CJ, Smith AV, Ingelsson E, O'Connell JR, Mangino M, M├Ągi R, Madden PA, Heath AC, Nyholt DR, Martin NG, Montgomery GW, Frayling TM, Hirschhorn JN, McCarthy MI, Goddard ME, Visscher PM; GIANT Consortium.

Eur J Hum Genet. 2011 Jul;19(7):807-12. doi: 10.1038/ejhg.2011.39. Epub 2011 Mar 16.

PMID:
21407268
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Ability to predict breast cancer in Asian women using a polygenic susceptibility model.

Hartman M, Suo C, Lim WY, Miao H, Teo YY, Chia KS.

Breast Cancer Res Treat. 2011 Jun;127(3):805-12. doi: 10.1007/s10549-010-1279-z. Epub 2010 Dec 14.

PMID:
21153878
[PubMed - indexed for MEDLINE]
9.

A compendium of genome-wide associations for cancer: critical synopsis and reappraisal.

Ioannidis JP, Castaldi P, Evangelou E.

J Natl Cancer Inst. 2010 Jun 16;102(12):846-58. doi: 10.1093/jnci/djq173. Epub 2010 May 26. Review.

PMID:
20505153
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Exploring the genetic architecture of circulating 25-hydroxyvitamin D.

Hiraki LT, Major JM, Chen C, Cornelis MC, Hunter DJ, Rimm EB, Simon KC, Weinstein SJ, Purdue MP, Yu K, Albanes D, Kraft P.

Genet Epidemiol. 2013 Jan;37(1):92-8. doi: 10.1002/gepi.21694. Epub 2012 Nov 7.

PMID:
23135809
[PubMed - indexed for MEDLINE]
Free PMC Article
11.
12.

Projecting the performance of risk prediction based on polygenic analyses of genome-wide association studies.

Chatterjee N, Wheeler B, Sampson J, Hartge P, Chanock SJ, Park JH.

Nat Genet. 2013 Apr;45(4):400-5, 405e1-3. doi: 10.1038/ng.2579. Epub 2013 Mar 3.

PMID:
23455638
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

A genome-wide association study identifies a breast cancer risk variant in ERBB4 at 2q34: results from the Seoul Breast Cancer Study.

Kim HC, Lee JY, Sung H, Choi JY, Park SK, Lee KM, Kim YJ, Go MJ, Li L, Cho YS, Park M, Kim DJ, Oh JH, Kim JW, Jeon JP, Jeon SY, Min H, Kim HM, Park J, Yoo KY, Noh DY, Ahn SH, Lee MH, Kim SW, Lee JW, Park BW, Park WY, Kim EH, Kim MK, Han W, Lee SA, Matsuo K, Shen CY, Wu PE, Hsiung CN, Lee JY, Kim HL, Han BG, Kang D.

Breast Cancer Res. 2012 Mar 27;14(2):R56.

PMID:
22452962
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

A genome-wide association study of breast and prostate cancer in the NHLBI's Framingham Heart Study.

Murabito JM, Rosenberg CL, Finger D, Kreger BE, Levy D, Splansky GL, Antman K, Hwang SJ.

BMC Med Genet. 2007 Sep 19;8 Suppl 1:S6.

PMID:
17903305
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Correcting "winner's curse" in odds ratios from genomewide association findings for major complex human diseases.

Zhong H, Prentice RL.

Genet Epidemiol. 2010 Jan;34(1):78-91. doi: 10.1002/gepi.20437.

PMID:
19639606
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Hints of hidden heritability in GWAS.

Gibson G.

Nat Genet. 2010 Jul;42(7):558-60. doi: 10.1038/ng0710-558.

PMID:
20581876
[PubMed - indexed for MEDLINE]
17.

Genetic determinants of mortality. Can findings from genome-wide association studies explain variation in human mortality?

Ganna A, Rivadeneira F, Hofman A, Uitterlinden AG, Magnusson PK, Pedersen NL, Ingelsson E, Tiemeier H.

Hum Genet. 2013 May;132(5):553-61. doi: 10.1007/s00439-013-1267-6. Epub 2013 Jan 25.

PMID:
23354976
[PubMed - indexed for MEDLINE]
18.

Evidence for further breast cancer susceptibility genes in addition to BRCA1 and BRCA2 in a population-based study.

Antoniou AC, Pharoah PD, McMullan G, Day NE, Ponder BA, Easton D.

Genet Epidemiol. 2001 Jul;21(1):1-18.

PMID:
11443730
[PubMed - indexed for MEDLINE]
19.

Genome-wide association studies in common cancers--what have we learnt?

Varghese JS, Easton DF.

Curr Opin Genet Dev. 2010 Jun;20(3):201-9. doi: 10.1016/j.gde.2010.03.012. Epub 2010 Apr 24. Review.

PMID:
20418093
[PubMed - indexed for MEDLINE]
20.

A role for common genomic variants in the assessment of familial breast cancer.

Sawyer S, Mitchell G, McKinley J, Chenevix-Trench G, Beesley J, Chen XQ, Bowtell D, Trainer AH, Harris M, Lindeman GJ, James PA.

J Clin Oncol. 2012 Dec 10;30(35):4330-6. doi: 10.1200/JCO.2012.41.7469. Epub 2012 Oct 29.

PMID:
23109704
[PubMed - indexed for MEDLINE]

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