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Items: 1 to 20 of 86


Identification of an mRNP complex regulating tumorigenesis at the translational elongation step.

Hussey GS, Chaudhury A, Dawson AE, Lindner DJ, Knudsen CR, Wilce MC, Merrick WC, Howe PH.

Mol Cell. 2011 Feb 18;41(4):419-31. doi: 10.1016/j.molcel.2011.02.003.


TGF-beta-mediated phosphorylation of hnRNP E1 induces EMT via transcript-selective translational induction of Dab2 and ILEI.

Chaudhury A, Hussey GS, Ray PS, Jin G, Fox PL, Howe PH.

Nat Cell Biol. 2010 Mar;12(3):286-93. doi: 10.1038/ncb2029. Epub 2010 Feb 14.


3'-UTR-mediated post-transcriptional regulation of cancer metastasis: beginning at the end.

Chaudhury A, Hussey GS, Howe PH.

RNA Biol. 2011 Jul-Aug;8(4):595-9. doi: 10.4161/rna.8.4.16018. Epub 2011 Jul 1.


ILEI drives epithelial to mesenchymal transition and metastatic progression in the lung cancer cell line A549.

Song Q, Sheng W, Zhang X, Jiao S, Li F.

Tumour Biol. 2014 Feb;35(2):1377-82. doi: 10.1007/s13277-013-1188-y. Epub 2013 Sep 27.


SchA-p85-FAK complex dictates isoform-specific activation of Akt2 and subsequent PCBP1-mediated post-transcriptional regulation of TGFβ-mediated epithelial to mesenchymal transition in human lung cancer cell line A549.

Xue X, Wang X, Liu Y, Teng G, Wang Y, Zang X, Wang K, Zhang J, Xu Y, Wang J, Pan L.

Tumour Biol. 2014 Aug;35(8):7853-9. doi: 10.1007/s13277-014-1982-1. Epub 2014 May 13.


MIR-99a and MIR-99b modulate TGF-β induced epithelial to mesenchymal plasticity in normal murine mammary gland cells.

Turcatel G, Rubin N, El-Hashash A, Warburton D.

PLoS One. 2012;7(1):e31032. doi: 10.1371/journal.pone.0031032. Epub 2012 Jan 27.


TGF-β stimulates Pyk2 expression as part of an epithelial-mesenchymal transition program required for metastatic outgrowth of breast cancer.

Wendt MK, Schiemann BJ, Parvani JG, Lee YH, Kang Y, Schiemann WP.

Oncogene. 2013 Apr 18;32(16):2005-15. doi: 10.1038/onc.2012.230. Epub 2012 Jun 18.


Stopped in translation: EMT control meets eukaryotic elongation.

Zhang YE.

Dev Cell. 2011 Mar 15;20(3):289-90. doi: 10.1016/j.devcel.2011.02.012.


Transforming growth factor-β-induced epithelial-mesenchymal transition facilitates epidermal growth factor-dependent breast cancer progression.

Wendt MK, Smith JA, Schiemann WP.

Oncogene. 2010 Dec 9;29(49):6485-98. doi: 10.1038/onc.2010.377. Epub 2010 Aug 30.


TGF-β-induced activation of mTOR complex 2 drives epithelial-mesenchymal transition and cell invasion.

Lamouille S, Connolly E, Smyth JW, Akhurst RJ, Derynck R.

J Cell Sci. 2012 Mar 1;125(Pt 5):1259-73. doi: 10.1242/jcs.095299. Epub 2012 Mar 7.


Establishment of a TGFβ-induced post-transcriptional EMT gene signature.

Hussey GS, Link LA, Brown AS, Howley BV, Chaudhury A, Howe PH.

PLoS One. 2012;7(12):e52624. doi: 10.1371/journal.pone.0052624. Epub 2012 Dec 20.


Identification and characterization of an hnRNP E1 translational silencing motif.

Brown AS, Mohanty BK, Howe PH.

Nucleic Acids Res. 2016 Apr 11. pii: gkw241. [Epub ahead of print]


Prostate apoptosis response-4 mediates TGF-β-induced epithelial-to-mesenchymal transition.

Chaudhry P, Fabi F, Singh M, Parent S, Leblanc V, Asselin E.

Cell Death Dis. 2014 Feb 6;5:e1044. doi: 10.1038/cddis.2014.7.


Deconstructing the mechanisms and consequences of TGF-β-induced EMT during cancer progression.

Wendt MK, Tian M, Schiemann WP.

Cell Tissue Res. 2012 Jan;347(1):85-101. doi: 10.1007/s00441-011-1199-1. Epub 2011 Jun 21. Review.


Therapeutic targeting of the focal adhesion complex prevents oncogenic TGF-beta signaling and metastasis.

Wendt MK, Schiemann WP.

Breast Cancer Res. 2009;11(5):R68. doi: 10.1186/bcr2360. Epub .


TGF-β signaling and epithelial-mesenchymal transition in cancer progression.

Katsuno Y, Lamouille S, Derynck R.

Curr Opin Oncol. 2013 Jan;25(1):76-84. doi: 10.1097/CCO.0b013e32835b6371. Review.

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