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Results: 1 to 20 of 118

1.

An embryonic stage-specific enhancer within the murine β-globin locus mediates domain-wide histone hyperacetylation.

Fromm G, Cadiz-Rivera B, de Vries C, Getman M, McGrath KE, Kingsley PD, Fields J, Fiering S, Bulger M.

Blood. 2011 May 12;117(19):5207-14. doi: 10.1182/blood-2010-08-302018. Epub 2011 Feb 14.

PMID:
21321362
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Histone hyperacetylation within the beta-globin locus is context-dependent and precedes high-level gene expression.

Fromm G, de Vries C, Byron R, Fields J, Fiering S, Groudine M, Bender MA, Palis J, Bulger M.

Blood. 2009 Oct 15;114(16):3479-88. doi: 10.1182/blood-2009-03-210690. Epub 2009 Aug 18.

PMID:
19690338
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

DNase I hypersensitivity and epsilon-globin transcriptional enhancement are separable in locus control region (LCR) HS1 mutant human beta-globin YAC transgenic mice.

Shimotsuma M, Okamura E, Matsuzaki H, Fukamizu A, Tanimoto K.

J Biol Chem. 2010 May 7;285(19):14495-503. doi: 10.1074/jbc.M110.116525. Epub 2010 Mar 15.

PMID:
20231293
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

The murine beta-globin locus control region regulates the rate of transcription but not the hyperacetylation of histones at the active genes.

Schübeler D, Groudine M, Bender MA.

Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11432-7. Epub 2001 Sep 11.

PMID:
11553791
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Sequences located 3' to the breakpoint of the hereditary persistence of fetal hemoglobin-3 deletion exhibit enhancer activity and can modify the developmental expression of the human fetal A gamma-globin gene in transgenic mice.

Anagnou NP, Perez-Stable C, Gelinas R, Costantini F, Liapaki K, Constantopoulou M, Kosteas T, Moschonas NK, Stamatoyannopoulos G.

J Biol Chem. 1995 Apr 28;270(17):10256-63.

PMID:
7537267
[PubMed - indexed for MEDLINE]
Free Article
6.

Developmental stage differences in chromatin subdomains of the beta-globin locus.

Kim A, Dean A.

Proc Natl Acad Sci U S A. 2004 May 4;101(18):7028-33. Epub 2004 Apr 22.

PMID:
15105444
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Chromatin structure of the LCR in the human β-globin locus transcribing the adult δ- and β-globin genes.

Kim S, Kim YW, Shim SH, Kim CG, Kim A.

Int J Biochem Cell Biol. 2012 Mar;44(3):505-13. doi: 10.1016/j.biocel.2011.12.001. Epub 2011 Dec 13.

PMID:
22178075
[PubMed - indexed for MEDLINE]
8.

Characterization of histone H3K27 modifications in the β-globin locus.

Kim YW, Kim A.

Biochem Biophys Res Commun. 2011 Feb 11;405(2):210-5. doi: 10.1016/j.bbrc.2011.01.010. Epub 2011 Jan 8.

PMID:
21219849
[PubMed - indexed for MEDLINE]
9.

Recruitment of transcription complexes to the beta-globin locus control region and transcription of hypersensitive site 3 prior to erythroid differentiation of murine embryonic stem cells.

Levings PP, Zhou Z, Vieira KF, Crusselle-Davis VJ, Bungert J.

FEBS J. 2006 Feb;273(4):746-55.

PMID:
16441661
[PubMed - indexed for MEDLINE]
10.

Juxtaposition of the HPFH2 enhancer is not sufficient to reactivate the gamma-globin gene in adult erythropoiesis.

Xiang P, Han H, Barkess G, Olave I, Fang X, Yin W, Stamatoyannopoulos G, Li Q.

Hum Mol Genet. 2005 Oct 15;14(20):3047-56. Epub 2005 Sep 9.

PMID:
16155112
[PubMed - indexed for MEDLINE]
Free Article
11.

Histone acetylation contributes to chromatin looping between the locus control region and globin gene by influencing hypersensitive site formation.

Kim YW, Kim A.

Biochim Biophys Acta. 2013 Sep;1829(9):963-9. doi: 10.1016/j.bbagrm.2013.04.006. Epub 2013 Apr 20.

PMID:
23607989
[PubMed - indexed for MEDLINE]
12.

The binding of the ubiquitous transcription factor Sp1 at the locus control region represses the expression of beta-like globin genes.

Feng D, Kan YW.

Proc Natl Acad Sci U S A. 2005 Jul 12;102(28):9896-900. Epub 2005 Jul 5.

PMID:
15998736
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Nuclear localization and histone acetylation: a pathway for chromatin opening and transcriptional activation of the human beta-globin locus.

Schübeler D, Francastel C, Cimbora DM, Reik A, Martin DI, Groudine M.

Genes Dev. 2000 Apr 15;14(8):940-50.

PMID:
10783166
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Transcription factors KLF1 and KLF2 positively regulate embryonic and fetal beta-globin genes through direct promoter binding.

Alhashem YN, Vinjamur DS, Basu M, Klingmüller U, Gaensler KM, Lloyd JA.

J Biol Chem. 2011 Jul 15;286(28):24819-27. doi: 10.1074/jbc.M111.247536. Epub 2011 May 24.

PMID:
21610079
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Developmental stage-specific epigenetic control of human beta-globin gene expression is potentiated in hematopoietic progenitor cells prior to their transcriptional activation.

Bottardi S, Aumont A, Grosveld F, Milot E.

Blood. 2003 Dec 1;102(12):3989-97. Epub 2003 Aug 14.

PMID:
12920025
[PubMed - indexed for MEDLINE]
Free Article
16.

Human beta-globin locus control region HS5 contains CTCF- and developmental stage-dependent enhancer-blocking activity in erythroid cells.

Tanimoto K, Sugiura A, Omori A, Felsenfeld G, Engel JD, Fukamizu A.

Mol Cell Biol. 2003 Dec;23(24):8946-52.

PMID:
14645507
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Developmentally dynamic histone acetylation pattern of a tissue-specific chromatin domain.

Forsberg EC, Downs KM, Christensen HM, Im H, Nuzzi PA, Bresnick EH.

Proc Natl Acad Sci U S A. 2000 Dec 19;97(26):14494-9.

PMID:
11121052
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

All of the human beta-type globin genes compete for LCR enhancer activity in embryonic erythroid cells of yeast artificial chromosome transgenic mice.

Okamura E, Matsuzaki H, Campbell AD, Engel JD, Fukamizu A, Tanimoto K.

FASEB J. 2009 Dec;23(12):4335-43. doi: 10.1096/fj.09-137778. Epub 2009 Aug 18.

PMID:
19690216
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

A major role for the TATA box in recruitment of chromatin modifying complexes to a globin gene promoter.

Gui CY, Dean A.

Proc Natl Acad Sci U S A. 2003 Jun 10;100(12):7009-14. Epub 2003 May 28.

PMID:
12773626
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

A WW domain-binding motif within the activation domain of the hematopoietic transcription factor NF-E2 is essential for establishment of a tissue-specific histone modification pattern.

Kiekhaefer CM, Boyer ME, Johnson KD, Bresnick EH.

J Biol Chem. 2004 Feb 27;279(9):7456-61. Epub 2003 Nov 2.

PMID:
14597626
[PubMed - indexed for MEDLINE]
Free Article

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