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Items: 1 to 20 of 143


A high fat diet increases mitochondrial fatty acid oxidation and uncoupling to decrease efficiency in rat heart.

Cole MA, Murray AJ, Cochlin LE, Heather LC, McAleese S, Knight NS, Sutton E, Jamil AA, Parassol N, Clarke K.

Basic Res Cardiol. 2011 May;106(3):447-57. doi: 10.1007/s00395-011-0156-1. Epub 2011 Feb 12.


UCP3 regulates cardiac efficiency and mitochondrial coupling in high fat-fed mice but not in leptin-deficient mice.

Boudina S, Han YH, Pei S, Tidwell TJ, Henrie B, Tuinei J, Olsen C, Sena S, Abel ED.

Diabetes. 2012 Dec;61(12):3260-9. doi: 10.2337/db12-0063. Epub 2012 Aug 21.


Increased mitochondrial uncoupling proteins, respiratory uncoupling and decreased efficiency in the chronically infarcted rat heart.

Murray AJ, Cole MA, Lygate CA, Carr CA, Stuckey DJ, Little SE, Neubauer S, Clarke K.

J Mol Cell Cardiol. 2008 Apr;44(4):694-700. doi: 10.1016/j.yjmcc.2008.01.008. Epub 2008 Feb 9.


Metabolic adaptation follows contractile dysfunction in the heart of obese Zucker rats fed a high-fat "Western" diet.

Burgmaier M, Sen S, Philip F, Wilson CR, Miller CC 3rd, Young ME, Taegtmeyer H.

Obesity (Silver Spring). 2010 Oct;18(10):1895-901. doi: 10.1038/oby.2009.500. Epub 2010 Jan 28.


De novo expression of uncoupling protein 3 is associated to enhanced mitochondrial thioesterase-1 expression and fatty acid metabolism in liver of fenofibrate-treated rats.

Lanni A, Mancini FP, Sabatino L, Silvestri E, Franco R, De Rosa G, Goglia F, Colantuoni V.

FEBS Lett. 2002 Aug 14;525(1-3):7-12.


Induction of endogenous uncoupling protein 3 suppresses mitochondrial oxidant emission during fatty acid-supported respiration.

Anderson EJ, Yamazaki H, Neufer PD.

J Biol Chem. 2007 Oct 26;282(43):31257-66. Epub 2007 Aug 30.


Type 1 diabetic akita mouse hearts are insulin sensitive but manifest structurally abnormal mitochondria that remain coupled despite increased uncoupling protein 3.

Bugger H, Boudina S, Hu XX, Tuinei J, Zaha VG, Theobald HA, Yun UJ, McQueen AP, Wayment B, Litwin SE, Abel ED.

Diabetes. 2008 Nov;57(11):2924-32. doi: 10.2337/db08-0079. Epub 2008 Aug 4.


Deterioration of physical performance and cognitive function in rats with short-term high-fat feeding.

Murray AJ, Knight NS, Cochlin LE, McAleese S, Deacon RM, Rawlins JN, Clarke K.

FASEB J. 2009 Dec;23(12):4353-60. doi: 10.1096/fj.09-139691. Epub 2009 Aug 10.


Interactions between the consumption of a high-fat diet and fasting in the regulation of fatty acid oxidation enzyme gene expression: an evaluation of potential mechanisms.

Frier BC, Jacobs RL, Wright DC.

Am J Physiol Regul Integr Comp Physiol. 2011 Feb;300(2):R212-21. doi: 10.1152/ajpregu.00367.2010. Epub 2010 Nov 17.


Liver mitochondrial properties from the obesity-resistant Lou/C rat.

Lacraz G, Couturier K, Taleux N, Servais S, Sibille B, Letexier D, Guigas B, Dubouchaud H, Leverve X, Favier R.

Int J Obes (Lond). 2008 Apr;32(4):629-38. doi: 10.1038/sj.ijo.0803779. Epub 2008 Jan 15.


Activation of a novel long-chain free fatty acid generation and export system in mitochondria of diabetic rat hearts.

Gerber LK, Aronow BJ, Matlib MA.

Am J Physiol Cell Physiol. 2006 Dec;291(6):C1198-207. Epub 2006 Jul 19.


Fasting, lipid metabolism, and triiodothyronine in rat gastrocnemius muscle: interrelated roles of uncoupling protein 3, mitochondrial thioesterase, and coenzyme Q.

Moreno M, Lombardi A, De Lange P, Silvestri E, Ragni M, Lanni A, Goglia F.

FASEB J. 2003 Jun;17(9):1112-4. Epub 2003 Apr 8.


Impaired long-chain fatty acid oxidation and contractile dysfunction in the obese Zucker rat heart.

Young ME, Guthrie PH, Razeghi P, Leighton B, Abbasi S, Patil S, Youker KA, Taegtmeyer H.

Diabetes. 2002 Aug;51(8):2587-95.


Constitutive UCP3 overexpression at physiological levels increases mouse skeletal muscle capacity for fatty acid transport and oxidation.

Bezaire V, Spriet LL, Campbell S, Sabet N, Gerrits M, Bonen A, Harper ME.

FASEB J. 2005 Jun;19(8):977-9. Epub 2005 Apr 6.


Diabetes or peroxisome proliferator-activated receptor alpha agonist increases mitochondrial thioesterase I activity in heart.

King KL, Young ME, Kerner J, Huang H, O'Shea KM, Alexson SE, Hoppel CL, Stanley WC.

J Lipid Res. 2007 Jul;48(7):1511-7. Epub 2007 Apr 16.


In obese Zucker rats, lipids accumulate in the heart despite normal mitochondrial content, morphology and long-chain fatty acid oxidation.

Holloway GP, Snook LA, Harris RJ, Glatz JF, Luiken JJ, Bonen A.

J Physiol. 2011 Jan 1;589(Pt 1):169-80. doi: 10.1113/jphysiol.2010.198663. Epub 2010 Nov 1.


High-fat diet feeding elevates skeletal muscle uncoupling protein 3 levels but not its activity in rats.

Chou CJ, Cha MC, Jung DW, Boozer CN, Hashim SA, Pi-Sunyer FX.

Obes Res. 2001 May;9(5):313-9.


Evidence for mitochondrial thioesterase 1 as a peroxisome proliferator-activated receptor-alpha-regulated gene in cardiac and skeletal muscle.

Stavinoha MA, RaySpellicy JW, Essop MF, Graveleau C, Abel ED, Hart-Sailors ML, Mersmann HJ, Bray MS, Young ME.

Am J Physiol Endocrinol Metab. 2004 Nov;287(5):E888-95. Epub 2004 Aug 3.

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