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Results: 1 to 20 of 95

1.

[Synthesis of secasterol and 24-episecasterol and their toxicity in MCF-7 cells].

Khripach VA, Zhabinskiĭ VN, Gyliakevich OV, Konstantinova OV, Misharin AIu, Mekhtiev AR, Timofeev VP, Tkachev IaV.

Bioorg Khim. 2010 Nov-Dec;36(6):815-24. Russian.

PMID:
21317948
[PubMed - indexed for MEDLINE]
2.

[(22R,23R)-3beta-Hydroxy-22,23-epoxy-5alpha-ergost-8(14)-en-15-one: improved synthesis and toxicity to MCF-7 cells].

Mekhtiev AR, Timofeev VP, Misharin AIu.

Bioorg Khim. 2008 Nov-Dec;34(6):840-6. Russian.

PMID:
19088760
[PubMed - indexed for MEDLINE]
3.

New pyrazolic compounds as cytotoxic agents.

Bouabdallah I, M'Barek LA, Zyad A, Ramdani A, Zidane I, Melhaoui A.

Nat Prod Res. 2007 Apr;21(4):298-302.

PMID:
17479417
[PubMed - indexed for MEDLINE]
4.

First stereoselective total synthesis and anticancer activity of new amide alkaloids of roots of pepper.

Srinivas Ch, Sai Pavan Kumar ChN, China Raju B, Jayathirtha Rao V, Naidu VG, Ramakrishna S, Diwan PV.

Bioorg Med Chem Lett. 2009 Oct 15;19(20):5915-8. doi: 10.1016/j.bmcl.2009.08.056. Epub 2009 Aug 20.

PMID:
19733069
[PubMed - indexed for MEDLINE]
5.

Isolation, synthesis and structures of cytotoxic ginsenoside derivatives.

Lei J, Li X, Gong XJ, Zheng YN.

Molecules. 2007 Sep 5;12(9):2140-50.

PMID:
17962732
[PubMed - indexed for MEDLINE]
Free Article
6.

Synthesis of a new cytotoxic cephalostatin/ritterazine analogue from hecogenin and 22-epi-hippuristanol.

Poza JJ, Rodríguez J, Jiménez C.

Bioorg Med Chem. 2010 Jan 1;18(1):58-63. doi: 10.1016/j.bmc.2009.11.018. Epub 2009 Nov 12.

PMID:
19948408
[PubMed - indexed for MEDLINE]
7.

Further study on synthesis and evaluation of 3,16,20-polyoxygenated steroids of marine origin and their analogs as potent cytotoxic agents.

Bunyathaworn P, Boonananwong S, Kongkathip B, Kongkathip N.

Steroids. 2010 Jun;75(6):432-44. doi: 10.1016/j.steroids.2010.02.011. Epub 2010 Feb 24.

PMID:
20188119
[PubMed - indexed for MEDLINE]
8.

Synthesis, proapoptotic screening, and structure-activity relationships of novel aza-lupane triterpenoids.

Mar AA, Szotek EL, Koohang A, Flavin WP, Eiznhamer DA, Flavin MT, Xu ZQ.

Bioorg Med Chem Lett. 2010 Sep 15;20(18):5389-93. doi: 10.1016/j.bmcl.2010.07.120. Epub 2010 Aug 3.

PMID:
20719505
[PubMed - indexed for MEDLINE]
9.

New quinoxaline 1,4-di-N-oxides. Part 1: Hypoxia-selective cytotoxins and anticancer agents derived from quinoxaline 1,4-di-N-oxides.

Amin KM, Ismail MM, Noaman E, Soliman DH, Ammar YA.

Bioorg Med Chem. 2006 Oct 15;14(20):6917-23. Epub 2006 Jul 14.

PMID:
16843668
[PubMed - indexed for MEDLINE]
10.

Synthesis and antitumor activity of new retinobenzoic acids.

Khandare RP, Vaze KR, Bhat SV.

Chem Biodivers. 2011 May;8(5):841-9. doi: 10.1002/cbdv.201000116.

PMID:
21560232
[PubMed - indexed for MEDLINE]
11.

Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of hydroxylated 2,4-diphenyl-6-aryl pyridines.

Karki R, Thapa P, Kang MJ, Jeong TC, Nam JM, Kim HL, Na Y, Cho WJ, Kwon Y, Lee ES.

Bioorg Med Chem. 2010 May 1;18(9):3066-77. doi: 10.1016/j.bmc.2010.03.051. Epub 2010 Mar 27.

PMID:
20392646
[PubMed - indexed for MEDLINE]
12.

Characterization, synthesis and self-aggregation of (-)-alternarlactam: a new fungal cytotoxin with cyclopentenone and isoquinolinone scaffolds.

Zhang AH, Jiang N, Gu W, Ma J, Wang YR, Song YC, Tan RX.

Chemistry. 2010 Dec 27;16(48):14479-85. doi: 10.1002/chem.201002205.

PMID:
21038331
[PubMed - indexed for MEDLINE]
13.

Antitumor agents. 254. Synthesis and biological evaluation of novel neo-tanshinlactone analogues as potent anti-breast cancer agents.

Wang X, Nakagawa-Goto K, Bastow KF, Don MJ, Lin YL, Wu TS, Lee KH.

J Med Chem. 2006 Sep 7;49(18):5631-4.

PMID:
16942038
[PubMed - indexed for MEDLINE]
14.

Antitumor activity of imidazothioxanthones in murine and human tumor models in vitro and in vivo.

Varvaresou A, Iakovou K, Gikas E, Fichtner I, Fiebig HH, Kelland LR, Double JA, Bibby MC, Hendriks HR.

Anticancer Res. 2004 Mar-Apr;24(2B):907-19.

PMID:
15161044
[PubMed - indexed for MEDLINE]
Free Article
15.

Benzothiepin-derived molecular scaffolds for estrogen receptor modulators: synthesis and antagonistic effects in breast cancer cells.

Meegan MJ, Barrett I, Zimmermann J, Knox AJ, Zisterer DM, Lloyd DG.

J Enzyme Inhib Med Chem. 2007 Oct;22(5):655-66.

PMID:
18035834
[PubMed - indexed for MEDLINE]
16.

Synthesis and evaluation of novel 4-amino-4,6-androstadiene-3,17-dione: an analog of formestane.

Sharma SK, Zheng W, Joshua AV, Abrams DN, McEwan AJ.

Bioorg Med Chem Lett. 2008 Oct 15;18(20):5563-6. doi: 10.1016/j.bmcl.2008.09.018. Epub 2008 Sep 22.

PMID:
18815032
[PubMed - indexed for MEDLINE]
17.

Synthesis and structure-activity relationships of fenbufen amide analogs.

Lin KI, Yang CH, Huang CW, Jian JY, Huang YC, Yu CS.

Molecules. 2010 Dec 2;15(12):8796-803. doi: 10.3390/molecules15128796.

PMID:
21127465
[PubMed - indexed for MEDLINE]
Free Article
18.

Synthesis and biological activity of novel shikonin analogues.

Wang W, Dai M, Zhu C, Zhang J, Lin L, Ding J, Duan W.

Bioorg Med Chem Lett. 2009 Feb 1;19(3):735-7. doi: 10.1016/j.bmcl.2008.12.032. Epub 2008 Dec 11.

PMID:
19111464
[PubMed - indexed for MEDLINE]
19.

Novel naphthalimide-amino acid conjugates with flexible leucine moiety as side chain: design, synthesis and potential antitumor activity.

Wu A, Xu Y, Qian X.

Bioorg Med Chem. 2009 Jan 15;17(2):592-9. doi: 10.1016/j.bmc.2008.11.080. Epub 2008 Dec 7.

PMID:
19109022
[PubMed - indexed for MEDLINE]
20.

Synthesis, structure and hypoxic cytotoxicity of 3-amino-1,2,4-benzotriazine-1,4-dioxide derivatives.

Jiang F, Weng Q, Sheng R, Xia Q, He Q, Yang B, Hu Y.

Arch Pharm (Weinheim). 2007 May;340(5):258-63.

PMID:
17464965
[PubMed - indexed for MEDLINE]
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