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Items: 1 to 20 of 302

1.

Sequential activation and inactivation of Dishevelled in the Wnt/beta-catenin pathway by casein kinases.

Bernatik O, Ganji RS, Dijksterhuis JP, Konik P, Cervenka I, Polonio T, Krejci P, Schulte G, Bryja V.

J Biol Chem. 2011 Mar 25;286(12):10396-410. doi: 10.1074/jbc.M110.169870. Epub 2011 Feb 1.

2.

Negative regulation of Wnt signaling mediated by CK1-phosphorylated Dishevelled via Ror2.

Witte F, Bernatik O, Kirchner K, Masek J, Mahl A, Krejci P, Mundlos S, Schambony A, Bryja V, Stricker S.

FASEB J. 2010 Jul;24(7):2417-26. doi: 10.1096/fj.09-150615. Epub 2010 Mar 9.

3.
4.

Dpr Acts as a molecular switch, inhibiting Wnt signaling when unphosphorylated, but promoting Wnt signaling when phosphorylated by casein kinase Idelta/epsilon.

Teran E, Branscomb AD, Seeling JM.

PLoS One. 2009;4(5):e5522. doi: 10.1371/journal.pone.0005522. Epub 2009 May 15.

5.

Casein kinase Iepsilon modulates the signaling specificities of dishevelled.

Cong F, Schweizer L, Varmus H.

Mol Cell Biol. 2004 Mar;24(5):2000-11.

6.

Casein kinase 1 delta functions at the centrosome to mediate Wnt-3a-dependent neurite outgrowth.

Greer YE, Rubin JS.

J Cell Biol. 2011 Mar 21;192(6):993-1004. doi: 10.1083/jcb.201011111.

7.

Coordinated action of CK1 isoforms in canonical Wnt signaling.

Del Valle-Pérez B, Arqués O, Vinyoles M, de Herreros AG, Duñach M.

Mol Cell Biol. 2011 Jul;31(14):2877-88. doi: 10.1128/MCB.01466-10. Epub 2011 May 23.

8.

Site-specific casein kinase 1epsilon-dependent phosphorylation of Dishevelled modulates beta-catenin signaling.

Klimowski LK, Garcia BA, Shabanowitz J, Hunt DF, Virshup DM.

FEBS J. 2006 Oct;273(20):4594-602. Epub 2006 Sep 11.

9.

Functional analysis of dishevelled-3 phosphorylation identifies distinct mechanisms driven by casein kinase 1ϵ and frizzled5.

Bernatík O, Šedová K, Schille C, Ganji RS, Červenka I, Trantírek L, Schambony A, Zdráhal Z, Bryja V.

J Biol Chem. 2014 Aug 22;289(34):23520-33. doi: 10.1074/jbc.M114.590638. Epub 2014 Jul 3.

10.

Wnt-5a induces Dishevelled phosphorylation and dopaminergic differentiation via a CK1-dependent mechanism.

Bryja V, Schulte G, Rawal N, Grahn A, Arenas E.

J Cell Sci. 2007 Feb 15;120(Pt 4):586-95. Epub 2007 Jan 23.

11.

Breast cancer-specific mutations in CK1epsilon inhibit Wnt/beta-catenin and activate the Wnt/Rac1/JNK and NFAT pathways to decrease cell adhesion and promote cell migration.

Foldynová-Trantírková S, Sekyrová P, Tmejová K, Brumovská E, Bernatík O, Blankenfeldt W, Krejcí P, Kozubík A, Dolezal T, Trantírek L, Bryja V.

Breast Cancer Res. 2010;12(3):R30. doi: 10.1186/bcr2581. Epub 2010 May 27.

12.

Casein kinase 2 Is activated and essential for Wnt/beta-catenin signaling.

Gao Y, Wang HY.

J Biol Chem. 2006 Jul 7;281(27):18394-400. Epub 2006 May 3.

13.

CKIepsilon/discs overgrown promotes both Wnt-Fz/beta-catenin and Fz/PCP signaling in Drosophila.

Klein TJ, Jenny A, Djiane A, Mlodzik M.

Curr Biol. 2006 Jul 11;16(13):1337-43.

14.

Nuclear Dvl, c-Jun, beta-catenin, and TCF form a complex leading to stabilization of beta-catenin-TCF interaction.

Gan XQ, Wang JY, Xi Y, Wu ZL, Li YP, Li L.

J Cell Biol. 2008 Mar 24;180(6):1087-100. doi: 10.1083/jcb.200710050. Epub 2008 Mar 17.

15.
16.

Protease-activated receptor-1 (PAR1) acts via a novel Galpha13-dishevelled axis to stabilize beta-catenin levels.

Turm H, Maoz M, Katz V, Yin YJ, Offermanns S, Bar-Shavit R.

J Biol Chem. 2010 May 14;285(20):15137-48. doi: 10.1074/jbc.M109.072843. Epub 2010 Mar 11.

17.

Casein kinase I epsilon enhances the binding of Dvl-1 to Frat-1 and is essential for Wnt-3a-induced accumulation of beta-catenin.

Hino S, Michiue T, Asashima M, Kikuchi A.

J Biol Chem. 2003 Apr 18;278(16):14066-73. Epub 2003 Jan 28.

18.

A p120-catenin-CK1epsilon complex regulates Wnt signaling.

Casagolda D, Del Valle-Pérez B, Valls G, Lugilde E, Vinyoles M, Casado-Vela J, Solanas G, Batlle E, Reynolds AB, Casal JI, de Herreros AG, Duñach M.

J Cell Sci. 2010 Aug 1;123(Pt 15):2621-31. doi: 10.1242/jcs.067512.

19.

IC261 induces cell cycle arrest and apoptosis of human cancer cells via CK1δ/ɛ and Wnt/β-catenin independent inhibition of mitotic spindle formation.

Cheong JK, Nguyen TH, Wang H, Tan P, Voorhoeve PM, Lee SH, Virshup DM.

Oncogene. 2011 Jun 2;30(22):2558-69. doi: 10.1038/onc.2010.627. Epub 2011 Jan 24.

20.

Endogenous protein kinase CK2 participates in Wnt signaling in mammary epithelial cells.

Song DH, Sussman DJ, Seldin DC.

J Biol Chem. 2000 Aug 4;275(31):23790-7.

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