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Results: 1 to 20 of 131

1.

Krüppel-like family of transcription factor 9, a differentiation-associated transcription factor, suppresses Notch1 signaling and inhibits glioblastoma-initiating stem cells.

Ying M, Sang Y, Li Y, Guerrero-Cazares H, Quinones-Hinojosa A, Vescovi AL, Eberhart CG, Xia S, Laterra J.

Stem Cells. 2011 Jan;29(1):20-31. doi: 10.1002/stem.561.

PMID:
21280156
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Regulation of glioblastoma multiforme stem-like cells by inhibitor of DNA binding proteins and oligodendroglial lineage-associated transcription factors.

Wu Y, Richard JP, Wang SD, Rath P, Laterra J, Xia S.

Cancer Sci. 2012 Jun;103(6):1028-37. doi: 10.1111/j.1349-7006.2012.02260.x. Epub 2012 Apr 4.

PMID:
22380883
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

DNER, an epigenetically modulated gene, regulates glioblastoma-derived neurosphere cell differentiation and tumor propagation.

Sun P, Xia S, Lal B, Eberhart CG, Quinones-Hinojosa A, Maciaczyk J, Matsui W, Dimeco F, Piccirillo SM, Vescovi AL, Laterra J.

Stem Cells. 2009 Jul;27(7):1473-86. doi: 10.1002/stem.89.

PMID:
19544453
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Lipid metabolism enzyme ACSVL3 supports glioblastoma stem cell maintenance and tumorigenicity.

Sun P, Xia S, Lal B, Shi X, Yang KS, Watkins PA, Laterra J.

BMC Cancer. 2014 Jun 4;14:401. doi: 10.1186/1471-2407-14-401.

PMID:
24893952
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Level of Notch activation determines the effect on growth and stem cell-like features in glioblastoma multiforme neurosphere cultures.

Kristoffersen K, Villingshøj M, Poulsen HS, Stockhausen MT.

Cancer Biol Ther. 2013 Jul;14(7):625-37. doi: 10.4161/cbt.24595. Epub 2013 May 10.

PMID:
23792644
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Kruppel-like factor-9 (KLF9) inhibits glioblastoma stemness through global transcription repression and integrin α6 inhibition.

Ying M, Tilghman J, Wei Y, Guerrero-Cazares H, Quinones-Hinojosa A, Ji H, Laterra J.

J Biol Chem. 2014 Nov 21;289(47):32742-56. doi: 10.1074/jbc.M114.588988. Epub 2014 Oct 6.

PMID:
25288800
[PubMed - indexed for MEDLINE]
7.

A novel berbamine derivative inhibits cell viability and induces apoptosis in cancer stem-like cells of human glioblastoma, via up-regulation of miRNA-4284 and JNK/AP-1 signaling.

Yang F, Nam S, Brown CE, Zhao R, Starr R, Ma Y, Xie J, Horne DA, Malkas LH, Jove R, Hickey RJ.

PLoS One. 2014 Apr 14;9(4):e94443. doi: 10.1371/journal.pone.0094443. eCollection 2014. Erratum in: PLoS One. 2014;9(6):e100708. Ma, Yuelong [added]; Xie, Jun [added].

PMID:
24732116
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

c-Met signaling induces a reprogramming network and supports the glioblastoma stem-like phenotype.

Li Y, Li A, Glas M, Lal B, Ying M, Sang Y, Xia S, Trageser D, Guerrero-Cázares H, Eberhart CG, Quiñones-Hinojosa A, Scheffler B, Laterra J.

Proc Natl Acad Sci U S A. 2011 Jun 14;108(24):9951-6. doi: 10.1073/pnas.1016912108. Epub 2011 May 31.

PMID:
21628563
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

MiR-152 functions as a tumor suppressor in glioblastoma stem cells by targeting Krüppel-like factor 4.

Ma J, Yao Y, Wang P, Liu Y, Zhao L, Li Z, Li Z, Xue Y.

Cancer Lett. 2014 Dec 1;355(1):85-95. doi: 10.1016/j.canlet.2014.09.012. Epub 2014 Sep 10.

PMID:
25218589
[PubMed - indexed for MEDLINE]
10.

Resistance of glioblastoma-initiating cells to radiation mediated by the tumor microenvironment can be abolished by inhibiting transforming growth factor-β.

Hardee ME, Marciscano AE, Medina-Ramirez CM, Zagzag D, Narayana A, Lonning SM, Barcellos-Hoff MH.

Cancer Res. 2012 Aug 15;72(16):4119-29. doi: 10.1158/0008-5472.CAN-12-0546. Epub 2012 Jun 12.

PMID:
22693253
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts.

Fan X, Khaki L, Zhu TS, Soules ME, Talsma CE, Gul N, Koh C, Zhang J, Li YM, Maciaczyk J, Nikkhah G, Dimeco F, Piccirillo S, Vescovi AL, Eberhart CG.

Stem Cells. 2010 Jan;28(1):5-16. doi: 10.1002/stem.254.

PMID:
19904829
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Regulation of glioblastoma stem cells by retinoic acid: role for Notch pathway inhibition.

Ying M, Wang S, Sang Y, Sun P, Lal B, Goodwin CR, Guerrero-Cazares H, Quinones-Hinojosa A, Laterra J, Xia S.

Oncogene. 2011 Aug 4;30(31):3454-67. doi: 10.1038/onc.2011.58. Epub 2011 Mar 7.

PMID:
21383690
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Gliosarcoma stem cells undergo glial and mesenchymal differentiation in vivo.

deCarvalho AC, Nelson K, Lemke N, Lehman NL, Arbab AS, Kalkanis S, Mikkelsen T.

Stem Cells. 2010 Feb;28(2):181-90. doi: 10.1002/stem.264.

PMID:
19937755
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Human Brat ortholog TRIM3 is a tumor suppressor that regulates asymmetric cell division in glioblastoma.

Chen G, Kong J, Tucker-Burden C, Anand M, Rong Y, Rahman F, Moreno CS, Van Meir EG, Hadjipanayis CG, Brat DJ.

Cancer Res. 2014 Aug 15;74(16):4536-48. doi: 10.1158/0008-5472.CAN-13-3703. Epub 2014 Jun 19.

PMID:
24947043
[PubMed - indexed for MEDLINE]
15.

Inhibition of Notch signaling alters the phenotype of orthotopic tumors formed from glioblastoma multiforme neurosphere cells but does not hamper intracranial tumor growth regardless of endogene Notch pathway signature.

Kristoffersen K, Nedergaard MK, Villingshøj M, Borup R, Broholm H, Kjær A, Poulsen HS, Stockhausen MT.

Cancer Biol Ther. 2014 Jul;15(7):862-77. doi: 10.4161/cbt.28876. Epub 2014 Apr 22.

PMID:
24755988
[PubMed - indexed for MEDLINE]
16.

NPV-LDE-225 (Erismodegib) inhibits epithelial mesenchymal transition and self-renewal of glioblastoma initiating cells by regulating miR-21, miR-128, and miR-200.

Fu J, Rodova M, Nanta R, Meeker D, Van Veldhuizen PJ, Srivastava RK, Shankar S.

Neuro Oncol. 2013 Jun;15(6):691-706. doi: 10.1093/neuonc/not011. Epub 2013 Mar 12.

PMID:
23482671
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Differentiation of glioblastoma multiforme stem-like cells leads to downregulation of EGFR and EGFRvIII and decreased tumorigenic and stem-like cell potential.

Stockhausen MT, Kristoffersen K, Stobbe L, Poulsen HS.

Cancer Biol Ther. 2014 Feb;15(2):216-24. doi: 10.4161/cbt.26736. Epub 2013 Nov 1.

PMID:
24525857
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Hypoxia increases the expression of stem-cell markers and promotes clonogenicity in glioblastoma neurospheres.

Bar EE, Lin A, Mahairaki V, Matsui W, Eberhart CG.

Am J Pathol. 2010 Sep;177(3):1491-502. doi: 10.2353/ajpath.2010.091021. Epub 2010 Jul 29.

PMID:
20671264
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Effect of the STAT3 inhibitor STX-0119 on the proliferation of cancer stem-like cells derived from recurrent glioblastoma.

Ashizawa T, Miyata H, Iizuka A, Komiyama M, Oshita C, Kume A, Nogami M, Yagoto M, Ito I, Oishi T, Watanabe R, Mitsuya K, Matsuno K, Furuya T, Okawara T, Otsuka M, Ogo N, Asai A, Nakasu Y, Yamaguchi K, Akiyama Y.

Int J Oncol. 2013 Jul;43(1):219-27. doi: 10.3892/ijo.2013.1916. Epub 2013 Apr 23.

PMID:
23612755
[PubMed - indexed for MEDLINE]
20.

STAT3 is required for proliferation and maintenance of multipotency in glioblastoma stem cells.

Sherry MM, Reeves A, Wu JK, Cochran BH.

Stem Cells. 2009 Oct;27(10):2383-92. doi: 10.1002/stem.185.

PMID:
19658181
[PubMed - indexed for MEDLINE]
Free Article
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