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Results: 1 to 20 of 102

1.

Insufficient activation of autophagy allows cellular damage to accumulate in critically ill patients.

Vanhorebeek I, Gunst J, Derde S, Derese I, Boussemaere M, Güiza F, Martinet W, Timmermans JP, D'Hoore A, Wouters PJ, Van den Berghe G.

J Clin Endocrinol Metab. 2011 Apr;96(4):E633-45. doi: 10.1210/jc.2010-2563. Epub 2011 Jan 26.

PMID:
21270330
[PubMed - indexed for MEDLINE]
2.

Mitochondrial fusion, fission, and biogenesis in prolonged critically ill patients.

Vanhorebeek I, Gunst J, Derde S, Derese I, Boussemaere M, D'Hoore A, Wouters PJ, Van den Berghe G.

J Clin Endocrinol Metab. 2012 Jan;97(1):E59-64. doi: 10.1210/jc.2011-1760. Epub 2011 Oct 19.

PMID:
22013100
[PubMed - indexed for MEDLINE]
3.

Insufficient autophagy contributes to mitochondrial dysfunction, organ failure, and adverse outcome in an animal model of critical illness.

Gunst J, Derese I, Aertgeerts A, Ververs EJ, Wauters A, Van den Berghe G, Vanhorebeek I.

Crit Care Med. 2013 Jan;41(1):182-94. doi: 10.1097/CCM.0b013e3182676657.

PMID:
23222264
[PubMed - indexed for MEDLINE]
4.

Early parenteral nutrition evokes a phenotype of autophagy deficiency in liver and skeletal muscle of critically ill rabbits.

Derde S, Vanhorebeek I, Güiza F, Derese I, Gunst J, Fahrenkrog B, Martinet W, Vervenne H, Ververs EJ, Larsson L, Van den Berghe G.

Endocrinology. 2012 May;153(5):2267-76. doi: 10.1210/en.2011-2068. Epub 2012 Mar 6.

PMID:
22396453
[PubMed - indexed for MEDLINE]
5.

Impact of hyperglycemia on neuropathological alterations during critical illness.

Sonneville R, den Hertog HM, Güiza F, Gunst J, Derese I, Wouters PJ, Brouland JP, Polito A, Gray F, Chrétien F, Charlier P, Annane D, Sharshar T, Van den Berghe G, Vanhorebeek I.

J Clin Endocrinol Metab. 2012 Jun;97(6):2113-23. doi: 10.1210/jc.2011-2971. Epub 2012 Mar 22.

PMID:
22442271
[PubMed - indexed for MEDLINE]
6.

Effect of intensive insulin therapy on insulin sensitivity in the critically ill.

Langouche L, Vander Perre S, Wouters PJ, D'Hoore A, Hansen TK, Van den Berghe G.

J Clin Endocrinol Metab. 2007 Oct;92(10):3890-7. Epub 2007 Jul 31.

PMID:
17666481
[PubMed - indexed for MEDLINE]
7.

Muscle atrophy and preferential loss of myosin in prolonged critically ill patients.

Derde S, Hermans G, Derese I, Güiza F, Hedström Y, Wouters PJ, Bruyninckx F, D'Hoore A, Larsson L, Van den Berghe G, Vanhorebeek I.

Crit Care Med. 2012 Jan;40(1):79-89. doi: 10.1097/CCM.0b013e31822d7c18.

PMID:
21926599
[PubMed - indexed for MEDLINE]
8.

Increasing intravenous glucose load in the presence of normoglycemia: effect on outcome and metabolism in critically ill rabbits.

Derde S, Vanhorebeek I, Ververs EJ, Vanhees I, Darras VM, Van Herck E, Larsson L, Van den Berghe G.

Crit Care Med. 2010 Feb;38(2):602-11. doi: 10.1097/CCM.0b013e3181c03f65.

PMID:
19851097
[PubMed - indexed for MEDLINE]
9.

Intensive insulin therapy protects the endothelium of critically ill patients.

Langouche L, Vanhorebeek I, Vlasselaers D, Vander Perre S, Wouters PJ, Skogstrand K, Hansen TK, Van den Berghe G.

J Clin Invest. 2005 Aug;115(8):2277-86.

PMID:
16075063
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Endocrine and metabolic disturbances in critical illness: relation to mechanisms of organ dysfunction and adverse outcome.

Langouche L, Mesotten D, Vanhorebeek I.

Verh K Acad Geneeskd Belg. 2010;72(3-4):149-63. Review.

PMID:
21067067
[PubMed - indexed for MEDLINE]
11.

Protection of hepatocyte mitochondrial ultrastructure and function by strict blood glucose control with insulin in critically ill patients.

Vanhorebeek I, De Vos R, Mesotten D, Wouters PJ, De Wolf-Peeters C, Van den Berghe G.

Lancet. 2005 Jan 1-7;365(9453):53-9.

PMID:
15639679
[PubMed - indexed for MEDLINE]
12.

Tissue-specific glucose toxicity induces mitochondrial damage in a burn injury model of critical illness.

Vanhorebeek I, Ellger B, De Vos R, Boussemaere M, Debaveye Y, Perre SV, Rabbani N, Thornalley PJ, Van den Berghe G.

Crit Care Med. 2009 Apr;37(4):1355-64. doi: 10.1097/CCM.0b013e31819cec17.

PMID:
19242345
[PubMed - indexed for MEDLINE]
13.

Reduced activation and increased inactivation of thyroid hormone in tissues of critically ill patients.

Peeters RP, Wouters PJ, Kaptein E, van Toor H, Visser TJ, Van den Berghe G.

J Clin Endocrinol Metab. 2003 Jul;88(7):3202-11.

PMID:
12843166
[PubMed - indexed for MEDLINE]
14.

Cortisol response to critical illness: effect of intensive insulin therapy.

Vanhorebeek I, Peeters RP, Vander Perre S, Jans I, Wouters PJ, Skogstrand K, Hansen TK, Bouillon R, Van den Berghe G.

J Clin Endocrinol Metab. 2006 Oct;91(10):3803-13. Epub 2006 Jul 25.

PMID:
16868064
[PubMed - indexed for MEDLINE]
15.

Insulin therapy for the critically ill patient.

Van den Berghe G.

Clin Cornerstone. 2003;5(2):56-63. Review.

PMID:
12800480
[PubMed - indexed for MEDLINE]
16.

Impaired autophagy, chaperone expression, and protein synthesis in response to critical illness interventions in porcine skeletal muscle.

Banduseela VC, Chen YW, Kultima HG, Norman HS, Aare S, Radell P, Eriksson LI, Hoffman EP, Larsson L.

Physiol Genomics. 2013 Jun 17;45(12):477-86. doi: 10.1152/physiolgenomics.00141.2012. Epub 2013 Apr 9.

PMID:
23572537
[PubMed - indexed for MEDLINE]
Free Article
17.

Intensive insulin therapy in critically ill patients.

van den Berghe G, Wouters P, Weekers F, Verwaest C, Bruyninckx F, Schetz M, Vlasselaers D, Ferdinande P, Lauwers P, Bouillon R.

N Engl J Med. 2001 Nov 8;345(19):1359-67.

PMID:
11794168
[PubMed - indexed for MEDLINE]
Free Article
18.

Enhanced autophagy plays a cardinal role in mitochondrial dysfunction in type 2 diabetic Goto-Kakizaki (GK) rats: ameliorating effects of (-)-epigallocatechin-3-gallate.

Yan J, Feng Z, Liu J, Shen W, Wang Y, Wertz K, Weber P, Long J, Liu J.

J Nutr Biochem. 2012 Jul;23(7):716-24. doi: 10.1016/j.jnutbio.2011.03.014. Epub 2011 Aug 4.

PMID:
21820301
[PubMed - indexed for MEDLINE]
19.

Role of intravenous insulin therapy in critically ill patients.

Van den Berghe GH.

Endocr Pract. 2004 Mar-Apr;10 Suppl 2:17-20. Review.

PMID:
15251636
[PubMed - indexed for MEDLINE]
20.

The role of insulin therapy in critically ill patients.

Langouche L, Vanhorebeek I, Van den Berghe G.

Treat Endocrinol. 2005;4(6):353-60. Review.

PMID:
16318401
[PubMed - indexed for MEDLINE]

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