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Results: 1 to 20 of 97

1.

N-acetylcysteine as a novel prophylactic treatment for ifosfamide-induced nephrotoxicity in children: translational pharmacokinetics.

Hanly LN, Chen N, Aleksa K, Cutler M, Bajcetic M, Palassery R, Regueira O, Turner C, Baw B, Malkin B, Freeman D, Rieder MJ, Vasylyeva TL, Koren G.

J Clin Pharmacol. 2012 Jan;52(1):55-64. doi: 10.1177/0091270010391790. Epub 2011 Jan 24.

PMID:
21263015
[PubMed - indexed for MEDLINE]
2.

Prevention of ifosfamide nephrotoxicity by N-acetylcysteine: clinical pharmacokinetic considerations.

Chen N, Aleksa K, Woodland C, Rieder M, Koren G.

Can J Clin Pharmacol. 2007 Summer;14(2):e246-50. Epub 2007 Jul 24. Review.

PMID:
17652768
[PubMed - indexed for MEDLINE]
Free Article
3.

The effect of N-acetylcysteine on ifosfamide-induced nephrotoxicity: in vitro studies in renal tubular cells.

Chen N, Aleksa K, Woodland C, Rieder M, Koren G.

Transl Res. 2007 Jul;150(1):51-7. Epub 2007 May 23.

PMID:
17585863
[PubMed - indexed for MEDLINE]
4.

N-Acetylcysteine prevents ifosfamide-induced nephrotoxicity in rats.

Chen N, Aleksa K, Woodland C, Rieder M, Koren G.

Br J Pharmacol. 2008 Apr;153(7):1364-72. doi: 10.1038/bjp.2008.15. Epub 2008 Feb 18.

PMID:
18278066
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Ifosfamide nephrotoxicity in children: a mechanistic base for pharmacological prevention.

Hanly L, Chen N, Rieder M, Koren G.

Expert Opin Drug Saf. 2009 Mar;8(2):155-68. doi: 10.1517/14740330902808169 . Review.

PMID:
19309244
[PubMed - indexed for MEDLINE]
6.

The effect of N-acetylcysteine on the antitumor activity of ifosfamide.

Chen N, Hanly L, Rieder M, Yeger H, Koren G.

Can J Physiol Pharmacol. 2011 May;89(5):335-43. doi: 10.1139/y11-028. Epub 2011 May 24.

PMID:
21609276
[PubMed - indexed for MEDLINE]
7.

Ifosfamide nephrotoxicity: limited influence of metabolism and mode of administration during repeated therapy in paediatrics.

Boddy AV, English M, Pearson AD, Idle JR, Skinner R.

Eur J Cancer. 1996 Jun;32A(7):1179-84.

PMID:
8758250
[PubMed - indexed for MEDLINE]
8.

N-acetylcysteine rescue protocol for nephrotoxicity in children caused by ifosfamide.

Hanly L, Rieder MJ, Huang SH, Vasylyeva TL, Shah RK, Regueira O, Koren G.

J Popul Ther Clin Pharmacol. 2013;20(2):e132-45. Epub 2013 Jun 13.

PMID:
23775286
[PubMed - indexed for MEDLINE]
Free Article
9.

The effects of N-acetylcysteine and ozone therapy on oxidative stress and inflammation in acetaminophen-induced nephrotoxicity model.

Ucar F, Taslipinar MY, Alp BF, Aydin I, Aydin FN, Agilli M, Toygar M, Ozkan E, Macit E, Oztosun M, Cayci T, Ozcan A.

Ren Fail. 2013;35(5):640-7. doi: 10.3109/0886022X.2013.780530. Epub 2013 Apr 8.

PMID:
23560513
[PubMed - indexed for MEDLINE]
10.

A dosing regimen for immediate N-acetylcysteine treatment for acute paracetamol overdose.

Shen F, Coulter CV, Isbister GK, Duffull SB.

Clin Toxicol (Phila). 2011 Aug;49(7):643-7. doi: 10.3109/15563650.2011.604034. Epub 2011 Aug 19.

PMID:
21854081
[PubMed - indexed for MEDLINE]
11.

The relationship between N-acetylcysteine, hyperbaric oxygen, and inflammation in a rat model of acetaminophen-induced nephrotoxicity.

Cermik H, Taslipinar MY, Aydin I, Agilli M, Aydin FN, Ucar F, Alp BF, Toygar M, Ozkan E, Altayli E, Cayci T.

Inflammation. 2013 Oct;36(5):1145-52. doi: 10.1007/s10753-013-9649-4.

PMID:
23624663
[PubMed - indexed for MEDLINE]
12.

Ifosfamide nephrotoxicity in pediatric cancer patients.

Lee BS, Lee JH, Kang HG, Hahn H, Lee JH, Shin HY, Ha IS, Cheong HI, Ahn HS, Choi Y.

Pediatr Nephrol. 2001 Oct;16(10):796-9.

PMID:
11605785
[PubMed - indexed for MEDLINE]
13.

Shorter duration of oral N-acetylcysteine therapy for acute acetaminophen overdose.

Woo OF, Mueller PD, Olson KR, Anderson IB, Kim SY.

Ann Emerg Med. 2000 Apr;35(4):363-8.

PMID:
10736123
[PubMed - indexed for MEDLINE]
14.

Efficacy of oral versus intravenous N-acetylcysteine in acetaminophen overdose: results of an open-label, clinical trial.

Perry HE, Shannon MW.

J Pediatr. 1998 Jan;132(1):149-52.

PMID:
9470017
[PubMed - indexed for MEDLINE]
15.

Protective effects of alpha lipoic acid versus N-acetylcysteine on ifosfamide-induced nephrotoxicity.

El-Sisi AE, El-Syaad ME, El-Desoky KI, Moussa EA.

Toxicol Ind Health. 2013 Jan 8. [Epub ahead of print]

PMID:
23299189
[PubMed - as supplied by publisher]
16.

Possible mechanisms for N-acetyl cysteine and taurine in ameliorating acute renal failure induced by cisplatin in rats.

Shalby AB, Assaf N, Ahmed HH.

Toxicol Mech Methods. 2011 Sep;21(7):538-46. doi: 10.3109/15376516.2011.568985. Epub 2011 Apr 7.

PMID:
21470069
[PubMed - indexed for MEDLINE]
17.

The Effects of N-acetylcysteine on ifosfamide efficacy in a mouse xenograft model.

Hanly L, Figueredo R, Rieder MJ, Koropatnick J, Koren G.

Anticancer Res. 2012 Sep;32(9):3791-8.

PMID:
22993321
[PubMed - indexed for MEDLINE]
18.

Comparison of the therapeutic efficacy of 4-methylpyrazole and N-acetylcysteine on acetaminophen (paracetamol) hepatotoxicity in rats.

Küçükardali Y, Cinan U, Acar HV, Ozkan S, Top C, Nalbant S, Cermik H, Cankir Z, Danaci M.

Curr Med Res Opin. 2002;18(2):78-81.

PMID:
12017214
[PubMed - indexed for MEDLINE]
19.

Comparison of the effects of N-acetyl cysteine and erdosteine in rats with renal injury caused by paracetamol intoxication.

Kandiş H, Erkan ME, Yildirim U, Güneş H, Erbaş M, Yildirim HA, Gezer S, Kara IH.

Hum Exp Toxicol. 2011 Sep;30(9):1350-8. doi: 10.1177/0960327110391384. Epub 2010 Nov 29.

PMID:
21115557
[PubMed - indexed for MEDLINE]
20.

Safety and efficacy of N-acetylcysteine in children with non-acetaminophen-induced acute liver failure.

Kortsalioudaki C, Taylor RM, Cheeseman P, Bansal S, Mieli-Vergani G, Dhawan A.

Liver Transpl. 2008 Jan;14(1):25-30.

PMID:
18161828
[PubMed - indexed for MEDLINE]
Free Article

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