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Results: 1 to 20 of 201

1.

Reduction of disulphide bonds unmasks potent antimicrobial activity of human β-defensin 1.

Schroeder BO, Wu Z, Nuding S, Groscurth S, Marcinowski M, Beisner J, Buchner J, Schaller M, Stange EF, Wehkamp J.

Nature. 2011 Jan 20;469(7330):419-23. doi: 10.1038/nature09674.

PMID:
21248850
[PubMed - indexed for MEDLINE]
2.

Immunology: Peptide gets in shape for self-defence.

Lehrer RI.

Nature. 2011 Jan 20;469(7330):309-10. doi: 10.1038/469309a. No abstract available.

PMID:
21248835
[PubMed - indexed for MEDLINE]
3.

Cell-mediated reduction of human β-defensin 1: a major role for mucosal thioredoxin.

Jaeger SU, Schroeder BO, Meyer-Hoffert U, Courth L, Fehr SN, Gersemann M, Stange EF, Wehkamp J.

Mucosal Immunol. 2013 Nov;6(6):1179-90. doi: 10.1038/mi.2013.17. Epub 2013 Apr 10.

PMID:
23571504
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Expression and regulation of the human beta-defensins hBD-1 and hBD-2 in intestinal epithelium.

O'Neil DA, Porter EM, Elewaut D, Anderson GM, Eckmann L, Ganz T, Kagnoff MF.

J Immunol. 1999 Dec 15;163(12):6718-24.

PMID:
10586069
[PubMed - indexed for MEDLINE]
Free Article
5.

Bactericidal activity of mouse α-defensin cryptdin-4 predominantly affects noncommensal bacteria.

Masuda K, Sakai N, Nakamura K, Yoshioka S, Ayabe T.

J Innate Immun. 2011;3(3):315-26. doi: 10.1159/000322037. Epub 2010 Nov 22.

PMID:
21099205
[PubMed - indexed for MEDLINE]
6.

Human beta-defensin 2 but not beta-defensin 1 is expressed preferentially in colonic mucosa of inflammatory bowel disease.

Wehkamp J, Fellermann K, Herrlinger KR, Baxmann S, Schmidt K, Schwind B, Duchrow M, Wohlschläger C, Feller AC, Stange EF.

Eur J Gastroenterol Hepatol. 2002 Jul;14(7):745-52.

PMID:
12169983
[PubMed - indexed for MEDLINE]
7.

Identification of a novel, multifunctional beta-defensin (human beta-defensin 3) with specific antimicrobial activity. Its interaction with plasma membranes of Xenopus oocytes and the induction of macrophage chemoattraction.

García JR, Jaumann F, Schulz S, Krause A, Rodríguez-Jiménez J, Forssmann U, Adermann K, Klüver E, Vogelmeier C, Becker D, Hedrich R, Forssmann WG, Bals R.

Cell Tissue Res. 2001 Nov;306(2):257-64.

PMID:
11702237
[PubMed - indexed for MEDLINE]
8.

Structure-activity relationships in defensin dimers: a novel link between beta-defensin tertiary structure and antimicrobial activity.

Campopiano DJ, Clarke DJ, Polfer NC, Barran PE, Langley RJ, Govan JR, Maxwell A, Dorin JR.

J Biol Chem. 2004 Nov 19;279(47):48671-9. Epub 2004 Aug 17.

PMID:
15317821
[PubMed - indexed for MEDLINE]
Free Article
9.

Isolation and characterization of human beta -defensin-3, a novel human inducible peptide antibiotic.

Harder J, Bartels J, Christophers E, Schroder JM.

J Biol Chem. 2001 Feb 23;276(8):5707-13. Epub 2000 Nov 20.

PMID:
11085990
[PubMed - indexed for MEDLINE]
Free Article
10.

Antimicrobial activities of human beta-defensins against Bacillus species.

Yadava P, Zhang C, Sun J, Hughes JA.

Int J Antimicrob Agents. 2006 Aug;28(2):132-7. Epub 2006 Jun 21.

PMID:
16797165
[PubMed - indexed for MEDLINE]
11.

Structural and functional characterization of hBD-1(Ser35), a peptide deduced from a DEFB1 polymorphism.

Circo R, Skerlavaj B, Gennaro R, Amoroso A, Zanetti M.

Biochem Biophys Res Commun. 2002 Apr 26;293(1):586-92.

PMID:
12054642
[PubMed - indexed for MEDLINE]
12.

Murine beta-defensin-3 is an inducible peptide with limited tissue expression and broad-spectrum antimicrobial activity.

Burd RS, Furrer JL, Sullivan J, Smith AL.

Shock. 2002 Nov;18(5):461-4.

PMID:
12412627
[PubMed - indexed for MEDLINE]
13.

[Human beta-defensin 1: from defence to offence].

Schroeder BO, Stange EF, Wehkamp J.

Z Gastroenterol. 2012 Nov;50(11):1171-5. doi: 10.1055/s-0032-1312865. Epub 2012 Nov 13. Review. German.

PMID:
23150110
[PubMed - indexed for MEDLINE]
14.

Human defensins.

Schneider JJ, Unholzer A, Schaller M, Schäfer-Korting M, Korting HC.

J Mol Med (Berl). 2005 Aug;83(8):587-95. Epub 2005 Apr 9. Review.

PMID:
15821901
[PubMed - indexed for MEDLINE]
15.

Structure-activity relation of human beta-defensin 3: influence of disulfide bonds and cysteine substitution on antimicrobial activity and cytotoxicity.

Klüver E, Schulz-Maronde S, Scheid S, Meyer B, Forssmann WG, Adermann K.

Biochemistry. 2005 Jul 19;44(28):9804-16.

PMID:
16008365
[PubMed - indexed for MEDLINE]
16.

Engineering disulfide bonds of the novel human beta-defensins hBD-27 and hBD-28: differences in disulfide formation and biological activity among human beta-defensins.

Schulz A, Klüver E, Schulz-Maronde S, Adermann K.

Biopolymers. 2005;80(1):34-49.

PMID:
15625724
[PubMed - indexed for MEDLINE]
17.

Immunomodulatory effects of Lactobacillus plantarum on human colon cancer cells.

Paolillo R, Romano Carratelli C, Sorrentino S, Mazzola N, Rizzo A.

Int Immunopharmacol. 2009 Oct;9(11):1265-71. doi: 10.1016/j.intimp.2009.07.008. Epub 2009 Jul 29.

PMID:
19647100
[PubMed - indexed for MEDLINE]
18.

Paneth cells, defensins, and the commensal microbiota: a hypothesis on intimate interplay at the intestinal mucosa.

Salzman NH, Underwood MA, Bevins CL.

Semin Immunol. 2007 Apr;19(2):70-83. Epub 2007 May 7. Review.

PMID:
17485224
[PubMed - indexed for MEDLINE]
19.

Large-scale synthesis and functional elements for the antimicrobial activity of defensins.

Raj PA, Antonyraj KJ, Karunakaran T.

Biochem J. 2000 May 1;347 Pt 3:633-41.

PMID:
10769165
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Human beta-defensin-1: A urinary peptide present in variant molecular forms and its putative functional implication.

Zucht HD, Grabowsky J, Schrader M, Liepke C, Jürgens M, Schulz-Knappe P, Forssmann WG.

Eur J Med Res. 1998 Jul 20;3(7):315-23.

PMID:
9682027
[PubMed - indexed for MEDLINE]

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