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Results: 1 to 20 of 257

1.

Myogenic Akt signaling attenuates muscular degeneration, promotes myofiber regeneration and improves muscle function in dystrophin-deficient mdx mice.

Kim MH, Kay DI, Rudra RT, Chen BM, Hsu N, Izumiya Y, Martinez L, Spencer MJ, Walsh K, Grinnell AD, Crosbie RH.

Hum Mol Genet. 2011 Apr 1;20(7):1324-38. doi: 10.1093/hmg/ddr015. Epub 2011 Jan 18.

PMID:
21245083
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Myogenic Akt signaling upregulates the utrophin-glycoprotein complex and promotes sarcolemma stability in muscular dystrophy.

Peter AK, Ko CY, Kim MH, Hsu N, Ouchi N, Rhie S, Izumiya Y, Zeng L, Walsh K, Crosbie RH.

Hum Mol Genet. 2009 Jan 15;18(2):318-27. doi: 10.1093/hmg/ddn358. Epub 2008 Nov 4.

PMID:
18986978
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Regulation of phosphatidylinositol 3-kinase (PI3K)/Akt and nuclear factor-kappa B signaling pathways in dystrophin-deficient skeletal muscle in response to mechanical stretch.

Dogra C, Changotra H, Wergedal JE, Kumar A.

J Cell Physiol. 2006 Sep;208(3):575-85.

PMID:
16741926
[PubMed - indexed for MEDLINE]
4.

Delivery of AAV2/9-microdystrophin genes incorporating helix 1 of the coiled-coil motif in the C-terminal domain of dystrophin improves muscle pathology and restores the level of α1-syntrophin and α-dystrobrevin in skeletal muscles of mdx mice.

Koo T, Malerba A, Athanasopoulos T, Trollet C, Boldrin L, Ferry A, Popplewell L, Foster H, Foster K, Dickson G.

Hum Gene Ther. 2011 Nov;22(11):1379-88. doi: 10.1089/hum.2011.020. Epub 2011 May 25.

PMID:
21453126
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Sub-physiological sarcoglycan expression contributes to compensatory muscle protection in mdx mice.

Li D, Long C, Yue Y, Duan D.

Hum Mol Genet. 2009 Apr 1;18(7):1209-20. doi: 10.1093/hmg/ddp015. Epub 2009 Jan 8.

PMID:
19131360
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Comparative proteomic profiling of soleus, extensor digitorum longus, flexor digitorum brevis and interosseus muscles from the mdx mouse model of Duchenne muscular dystrophy.

Carberry S, Brinkmeier H, Zhang Y, Winkler CK, Ohlendieck K.

Int J Mol Med. 2013 Sep;32(3):544-56. doi: 10.3892/ijmm.2013.1429. Epub 2013 Jul 3.

PMID:
23828267
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

MicroRNA-486-dependent modulation of DOCK3/PTEN/AKT signaling pathways improves muscular dystrophy-associated symptoms.

Alexander MS, Casar JC, Motohashi N, Vieira NM, Eisenberg I, Marshall JL, Gasperini MJ, Lek A, Myers JA, Estrella EA, Kang PB, Shapiro F, Rahimov F, Kawahara G, Widrick JJ, Kunkel LM.

J Clin Invest. 2014 Jun;124(6):2651-67. doi: 10.1172/JCI73579. Epub 2014 May 1.

PMID:
24789910
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Muscle-specific expression of insulin-like growth factor I counters muscle decline in mdx mice.

Barton ER, Morris L, Musaro A, Rosenthal N, Sweeney HL.

J Cell Biol. 2002 Apr 1;157(1):137-48. Epub 2002 Apr 1.

PMID:
11927606
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Akt activation prevents the force drop induced by eccentric contractions in dystrophin-deficient skeletal muscle.

Blaauw B, Mammucari C, Toniolo L, Agatea L, Abraham R, Sandri M, Reggiani C, Schiaffino S.

Hum Mol Genet. 2008 Dec 1;17(23):3686-96. doi: 10.1093/hmg/ddn264. Epub 2008 Aug 27.

PMID:
18753145
[PubMed - indexed for MEDLINE]
Free Article
10.

Expression profiling in stably regenerating skeletal muscle of dystrophin-deficient mdx mice.

Boer JM, de Meijer EJ, Mank EM, van Ommen GB, den Dunnen JT.

Neuromuscul Disord. 2002 Oct;12 Suppl 1:S118-24.

PMID:
12206806
[PubMed - indexed for MEDLINE]
12.

Microutrophin delivery through rAAV6 increases lifespan and improves muscle function in dystrophic dystrophin/utrophin-deficient mice.

Odom GL, Gregorevic P, Allen JM, Finn E, Chamberlain JS.

Mol Ther. 2008 Sep;16(9):1539-45. doi: 10.1038/mt.2008.149. Epub 2008 Jul 29.

PMID:
18665159
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Loss of sarcolemma nNOS in sarcoglycan-deficient muscle.

Crosbie RH, Barresi R, Campbell KP.

FASEB J. 2002 Nov;16(13):1786-91.

PMID:
12409321
[PubMed - indexed for MEDLINE]
Free Article
14.

Analysis of gene expression differences between utrophin/dystrophin-deficient vs mdx skeletal muscles reveals a specific upregulation of slow muscle genes in limb muscles.

Baker PE, Kearney JA, Gong B, Merriam AP, Kuhn DE, Porter JD, Rafael-Fortney JA.

Neurogenetics. 2006 May;7(2):81-91. Epub 2006 Mar 9.

PMID:
16525850
[PubMed - indexed for MEDLINE]
15.

Immune response to adenovirus-delivered antigens upregulates utrophin and results in mitigation of muscle pathology in mdx mice.

Yamamoto K, Yuasa K, Miyagoe Y, Hosaka Y, Tsukita K, Yamamoto H, Nabeshima YI, Takeda S.

Hum Gene Ther. 2000 Mar 20;11(5):669-80.

PMID:
10757347
[PubMed - indexed for MEDLINE]
16.

Enhanced expression of the alpha 7 beta 1 integrin reduces muscular dystrophy and restores viability in dystrophic mice.

Burkin DJ, Wallace GQ, Nicol KJ, Kaufman DJ, Kaufman SJ.

J Cell Biol. 2001 Mar 19;152(6):1207-18.

PMID:
11257121
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Preservation of muscle force in Mdx3cv mice correlates with low-level expression of a near full-length dystrophin protein.

Li D, Yue Y, Duan D.

Am J Pathol. 2008 May;172(5):1332-41. doi: 10.2353/ajpath.2008.071042. Epub 2008 Apr 1.

PMID:
18385524
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Differential effects of dystrophin and utrophin gene transfer in immunocompetent muscular dystrophy (mdx) mice.

Ebihara S, Guibinga GH, Gilbert R, Nalbantoglu J, Massie B, Karpati G, Petrof BJ.

Physiol Genomics. 2000 Sep 8;3(3):133-44.

PMID:
11015608
[PubMed - indexed for MEDLINE]
19.

Expression of full-length utrophin prevents muscular dystrophy in mdx mice.

Tinsley J, Deconinck N, Fisher R, Kahn D, Phelps S, Gillis JM, Davies K.

Nat Med. 1998 Dec;4(12):1441-4.

PMID:
9846586
[PubMed - indexed for MEDLINE]
20.

Overexpression of the cytotoxic T cell GalNAc transferase in skeletal muscle inhibits muscular dystrophy in mdx mice.

Nguyen HH, Jayasinha V, Xia B, Hoyte K, Martin PT.

Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5616-21.

PMID:
11960016
[PubMed - indexed for MEDLINE]
Free PMC Article
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