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Results: 1 to 20 of 99

1.

A brain slice culture model of viral encephalitis reveals an innate CNS cytokine response profile and the therapeutic potential of caspase inhibition.

Dionne KR, Leser JS, Lorenzen KA, Beckham JD, Tyler KL.

Exp Neurol. 2011 Apr;228(2):222-31. doi: 10.1016/j.expneurol.2011.01.006. Epub 2011 Jan 15.

PMID:
21241693
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Minocycline delays disease onset and mortality in reovirus encephalitis.

Richardson-Burns SM, Tyler KL.

Exp Neurol. 2005 Apr;192(2):331-9.

PMID:
15755550
[PubMed - indexed for MEDLINE]
3.

Caspase-3 activation is required for reovirus-induced encephalitis in vivo.

Beckham JD, Tuttle KD, Tyler KL.

J Neurovirol. 2010 Jul;16(4):306-17. doi: 10.3109/13550284.2010.499890.

PMID:
20626234
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Type I interferon signaling limits reoviral tropism within the brain and prevents lethal systemic infection.

Dionne KR, Galvin JM, Schittone SA, Clarke P, Tyler KL.

J Neurovirol. 2011 Aug;17(4):314-26. doi: 10.1007/s13365-011-0038-1. Epub 2011 Jun 14.

PMID:
21671121
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Novel strategy for treatment of viral central nervous system infection by using a cell-permeating inhibitor of c-Jun N-terminal kinase.

Beckham JD, Goody RJ, Clarke P, Bonny C, Tyler KL.

J Virol. 2007 Jul;81(13):6984-92. Epub 2007 May 2.

PMID:
17475657
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

The proapoptotic Bcl-2 protein Bax plays an important role in the pathogenesis of reovirus encephalitis.

Berens HM, Tyler KL.

J Virol. 2011 Apr;85(8):3858-71. doi: 10.1128/JVI.01958-10. Epub 2011 Feb 9.

PMID:
21307199
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Reovirus-induced neuronal apoptosis is mediated by caspase 3 and is associated with the activation of death receptors.

Richardson-Burns SM, Kominsky DJ, Tyler KL.

J Neurovirol. 2002 Oct;8(5):365-80.

PMID:
12402163
[PubMed - indexed for MEDLINE]
8.

Gene expression in the brain during reovirus encephalitis.

Tyler KL, Leser JS, Phang TL, Clarke P.

J Neurovirol. 2010 Feb;16(1):56-71. doi: 10.3109/13550280903586394.

PMID:
20158406
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Reovirus activates transforming growth factor beta and bone morphogenetic protein signaling pathways in the central nervous system that contribute to neuronal survival following infection.

Beckham JD, Tuttle K, Tyler KL.

J Virol. 2009 May;83(10):5035-45. doi: 10.1128/JVI.02433-08. Epub 2009 Mar 11.

PMID:
19279118
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Impact of direct virus-induced neuronal dysfunction and immunological damage on the progression of flavivirus (Modoc) encephalitis in a murine model.

Leyssen P, Paeshuyse J, Charlier N, Van Lommel A, Drosten C, De Clercq E, Neyts J.

J Neurovirol. 2003 Feb;9(1):69-78.

PMID:
12587070
[PubMed - indexed for MEDLINE]
11.

Slice culture modeling of central nervous system (CNS) viral infection.

Dionne KR, Tyler KL.

Methods Mol Biol. 2013;1078:97-117. doi: 10.1007/978-1-62703-640-5_9.

PMID:
23975824
[PubMed - indexed for MEDLINE]
12.

RNase L mediated protection from virus induced demyelination.

Ireland DD, Stohlman SA, Hinton DR, Kapil P, Silverman RH, Atkinson RA, Bergmann CC.

PLoS Pathog. 2009 Oct;5(10):e1000602. doi: 10.1371/journal.ppat.1000602. Epub 2009 Oct 2.

PMID:
19798426
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

JAK-STAT signaling pathways are activated in the brain following reovirus infection.

Goody RJ, Beckham JD, Rubtsova K, Tyler KL.

J Neurovirol. 2007 Aug;13(4):373-83.

PMID:
17849321
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Protection from brain damage and bacterial infection in murine stroke by the novel caspase-inhibitor Q-VD-OPH.

Braun JS, Prass K, Dirnagl U, Meisel A, Meisel C.

Exp Neurol. 2007 Aug;206(2):183-91. Epub 2007 May 21.

PMID:
17585906
[PubMed - indexed for MEDLINE]
16.

Fas-mediated apoptotic signaling in the mouse brain following reovirus infection.

Clarke P, Beckham JD, Leser JS, Hoyt CC, Tyler KL.

J Virol. 2009 Jun;83(12):6161-70. doi: 10.1128/JVI.02488-08. Epub 2009 Mar 25.

PMID:
19321603
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Neuroregulatory events follow adaptive immune-mediated elimination of HIV-1-infected macrophages: studies in a murine model of viral encephalitis.

Poluektova L, Gorantla S, Faraci J, Birusingh K, Dou H, Gendelman HE.

J Immunol. 2004 Jun 15;172(12):7610-7.

PMID:
15187141
[PubMed - indexed for MEDLINE]
Free Article
18.

Caspase inhibition protects against reovirus-induced myocardial injury in vitro and in vivo.

DeBiasi RL, Robinson BA, Sherry B, Bouchard R, Brown RD, Rizeq M, Long C, Tyler KL.

J Virol. 2004 Oct;78(20):11040-50.

PMID:
15452224
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Antibody inhibits defined stages in the pathogenesis of reovirus serotype 3 infection of the central nervous system.

Tyler KL, Virgin HW 4th, Bassel-Duby R, Fields BN.

J Exp Med. 1989 Sep 1;170(3):887-900.

PMID:
2549167
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Neuroprotective and anti-human immunodeficiency virus activity of minocycline.

Zink MC, Uhrlaub J, DeWitt J, Voelker T, Bullock B, Mankowski J, Tarwater P, Clements J, Barber S.

JAMA. 2005 Apr 27;293(16):2003-11.

PMID:
15855434
[PubMed - indexed for MEDLINE]

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