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Results: 1 to 20 of 108

1.

Genome-scale RNAi on living-cell microarrays identifies novel regulators of Drosophila melanogaster TORC1-S6K pathway signaling.

Lindquist RA, Ottina KA, Wheeler DB, Hsu PP, Thoreen CC, Guertin DA, Ali SM, Sengupta S, Shaul YD, Lamprecht MR, Madden KL, Papallo AR, Jones TR, Sabatini DM, Carpenter AE.

Genome Res. 2011 Mar;21(3):433-46. doi: 10.1101/gr.111492.110. Epub 2011 Jan 14.

PMID:
21239477
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

A role for p38 stress-activated protein kinase in regulation of cell growth via TORC1.

Cully M, Genevet A, Warne P, Treins C, Liu T, Bastien J, Baum B, Tapon N, Leevers SJ, Downward J.

Mol Cell Biol. 2010 Jan;30(2):481-95. doi: 10.1128/MCB.00688-09. Epub 2009 Nov 16.

PMID:
19917724
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Functional genomic analysis of the Wnt-wingless signaling pathway.

DasGupta R, Kaykas A, Moon RT, Perrimon N.

Science. 2005 May 6;308(5723):826-33. Epub 2005 Apr 7.

PMID:
15817814
[PubMed - indexed for MEDLINE]
Free Article
4.

A genome-wide RNA interference screen in Drosophila melanogaster cells for new components of the Hh signaling pathway.

Nybakken K, Vokes SA, Lin TY, McMahon AP, Perrimon N.

Nat Genet. 2005 Dec;37(12):1323-32. Epub 2005 Nov 20.

PMID:
16311596
[PubMed - indexed for MEDLINE]
5.

Fission yeast TORC1 regulates phosphorylation of ribosomal S6 proteins in response to nutrients and its activity is inhibited by rapamycin.

Nakashima A, Sato T, Tamanoi F.

J Cell Sci. 2010 Mar 1;123(Pt 5):777-86. doi: 10.1242/jcs.060319. Epub 2010 Feb 9.

PMID:
20144990
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

TSC1/TSC2 and Rheb have different effects on TORC1 and TORC2 activity.

Yang Q, Inoki K, Kim E, Guan KL.

Proc Natl Acad Sci U S A. 2006 May 2;103(18):6811-6. Epub 2006 Apr 20.

PMID:
16627617
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Advances in genome-wide RNAi cellular screens: a case study using the Drosophila JAK/STAT pathway.

Fisher KH, Wright VM, Taylor A, Zeidler MP, Brown S.

BMC Genomics. 2012 Sep 24;13:506. doi: 10.1186/1471-2164-13-506.

PMID:
23006893
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

TSC1/2 regulates intestinal stem cell maintenance and lineage differentiation through Rheb-TORC1-S6K but independently of nutritional status or Notch regulation.

Quan Z, Sun P, Lin G, Xi R.

J Cell Sci. 2013 Sep 1;126(Pt 17):3884-92. doi: 10.1242/jcs.125294. Epub 2013 Jul 10.

PMID:
23843608
[PubMed - indexed for MEDLINE]
Free Article
9.

In vivo RNAi screen reveals neddylation genes as novel regulators of Hedgehog signaling.

Du J, Zhang J, Su Y, Liu M, Ospina JK, Yang S, Zhu AJ.

PLoS One. 2011;6(9):e24168. doi: 10.1371/journal.pone.0024168. Epub 2011 Sep 8.

PMID:
21931660
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Tissue-specific coupling between insulin/IGF and TORC1 signaling via PRAS40 in Drosophila.

Pallares-Cartes C, Cakan-Akdogan G, Teleman AA.

Dev Cell. 2012 Jan 17;22(1):172-82. doi: 10.1016/j.devcel.2011.10.029.

PMID:
22264732
[PubMed - indexed for MEDLINE]
Free Article
11.

Signaling from Akt to FRAP/TOR targets both 4E-BP and S6K in Drosophila melanogaster.

Miron M, Lasko P, Sonenberg N.

Mol Cell Biol. 2003 Dec;23(24):9117-26.

PMID:
14645523
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Dynamic switch of negative feedback regulation in Drosophila Akt-TOR signaling.

Kockel L, Kerr KS, Melnick M, Brückner K, Hebrok M, Perrimon N.

PLoS Genet. 2010 Jun 17;6(6):e1000990. doi: 10.1371/journal.pgen.1000990.

PMID:
20585550
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Eye transformer is a negative regulator of Drosophila JAK/STAT signaling.

Kallio J, Myllymäki H, Grönholm J, Armstrong M, Vanha-aho LM, Mäkinen L, Silvennoinen O, Valanne S, Rämet M.

FASEB J. 2010 Nov;24(11):4467-79. doi: 10.1096/fj.10-162784. Epub 2010 Jul 12.

PMID:
20624926
[PubMed - indexed for MEDLINE]
Free Article
14.

Not4 enhances JAK/STAT pathway-dependent gene expression in Drosophila and in human cells.

Grönholm J, Kaustio M, Myllymäki H, Kallio J, Saarikettu J, Kronhamn J, Valanne S, Silvennoinen O, Rämet M.

FASEB J. 2012 Mar;26(3):1239-50. doi: 10.1096/fj.11-195875. Epub 2011 Dec 8.

PMID:
22159038
[PubMed - indexed for MEDLINE]
Free Article
15.

RNAi living-cell microarrays for loss-of-function screens in Drosophila melanogaster cells.

Wheeler DB, Bailey SN, Guertin DA, Carpenter AE, Higgins CO, Sabatini DM.

Nat Methods. 2004 Nov;1(2):127-32. Epub 2004 Oct 21.

PMID:
15782175
[PubMed - indexed for MEDLINE]
16.

Modifiers of notch transcriptional activity identified by genome-wide RNAi.

Mourikis P, Lake RJ, Firnhaber CB, DeDecker BS.

BMC Dev Biol. 2010 Oct 19;10:107. doi: 10.1186/1471-213X-10-107.

PMID:
20959007
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Identification of JAK/STAT signalling components by genome-wide RNA interference.

Müller P, Kuttenkeuler D, Gesellchen V, Zeidler MP, Boutros M.

Nature. 2005 Aug 11;436(7052):871-5.

PMID:
16094372
[PubMed - indexed for MEDLINE]
18.

A targeted in vivo RNAi screen reveals deubiquitinases as new regulators of Notch signaling.

Zhang J, Liu M, Su Y, Du J, Zhu AJ.

G3 (Bethesda). 2012 Dec;2(12):1563-75. doi: 10.1534/g3.112.003780. Epub 2012 Dec 1.

PMID:
23275879
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Ribosomal protein S6 kinase is a critical downstream effector of the target of rapamycin complex 1 for long-term facilitation in Aplysia.

Weatherill DB, Dyer J, Sossin WS.

J Biol Chem. 2010 Apr 16;285(16):12255-67. doi: 10.1074/jbc.M109.071142. Epub 2010 Feb 22.

PMID:
20177060
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Analysis of the transcriptomes downstream of Eyeless and the Hedgehog, Decapentaplegic and Notch signaling pathways in Drosophila melanogaster.

Nfonsam LE, Cano C, Mudge J, Schilkey FD, Curtiss J.

PLoS One. 2012;7(8):e44583. doi: 10.1371/journal.pone.0044583. Epub 2012 Aug 31.

PMID:
22952997
[PubMed - indexed for MEDLINE]
Free PMC Article

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