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Items: 1 to 20 of 85

1.

Genome-wide association studies: results from the first few years and potential implications for clinical medicine.

Hirschhorn JN, Gajdos ZK.

Annu Rev Med. 2011;62:11-24. doi: 10.1146/annurev.med.091708.162036. Review.

PMID:
21226609
2.

Hundreds of variants clustered in genomic loci and biological pathways affect human height.

Lango Allen H, Estrada K, Lettre G, Berndt SI, Weedon MN, Rivadeneira F, Willer CJ, Jackson AU, Vedantam S, Raychaudhuri S, Ferreira T, Wood AR, Weyant RJ, Segrè AV, Speliotes EK, Wheeler E, Soranzo N, Park JH, Yang J, Gudbjartsson D, Heard-Costa NL, Randall JC, Qi L, Vernon Smith A, Mägi R, Pastinen T, Liang L, Heid IM, Luan J, Thorleifsson G, Winkler TW, Goddard ME, Sin Lo K, Palmer C, Workalemahu T, Aulchenko YS, Johansson A, Zillikens MC, Feitosa MF, Esko T, Johnson T, Ketkar S, Kraft P, Mangino M, Prokopenko I, Absher D, Albrecht E, Ernst F, Glazer NL, Hayward C, Hottenga JJ, Jacobs KB, Knowles JW, Kutalik Z, Monda KL, Polasek O, Preuss M, Rayner NW, Robertson NR, Steinthorsdottir V, Tyrer JP, Voight BF, Wiklund F, Xu J, Zhao JH, Nyholt DR, Pellikka N, Perola M, Perry JR, Surakka I, Tammesoo ML, Altmaier EL, Amin N, Aspelund T, Bhangale T, Boucher G, Chasman DI, Chen C, Coin L, Cooper MN, Dixon AL, Gibson Q, Grundberg E, Hao K, Juhani Junttila M, Kaplan LM, Kettunen J, König IR, Kwan T, Lawrence RW, Levinson DF, Lorentzon M, McKnight B, Morris AP, Müller M, Suh Ngwa J, Purcell S, Rafelt S, Salem RM, Salvi E, Sanna S, Shi J, Sovio U, Thompson JR, Turchin MC, Vandenput L, Verlaan DJ, Vitart V, White CC, Ziegler A, Almgren P, Balmforth AJ, Campbell H, Citterio L, De Grandi A, Dominiczak A, Duan J, Elliott P, Elosua R, Eriksson JG, Freimer NB, Geus EJ, Glorioso N, Haiqing S, Hartikainen AL, Havulinna AS, Hicks AA, Hui J, Igl W, Illig T, Jula A, Kajantie E, Kilpeläinen TO, Koiranen M, Kolcic I, Koskinen S, Kovacs P, Laitinen J, Liu J, Lokki ML, Marusic A, Maschio A, Meitinger T, Mulas A, Paré G, Parker AN, Peden JF, Petersmann A, Pichler I, Pietiläinen KH, Pouta A, Ridderstråle M, Rotter JI, Sambrook JG, Sanders AR, Schmidt CO, Sinisalo J, Smit JH, Stringham HM, Bragi Walters G, Widen E, Wild SH, Willemsen G, Zagato L, Zgaga L, Zitting P, Alavere H, Farrall M, McArdle WL, Nelis M, Peters MJ, Ripatti S, van Meurs JB, Aben KK, Ardlie KG, Beckmann JS, Beilby JP, Bergman RN, Bergmann S, Collins FS, Cusi D, den Heijer M, Eiriksdottir G, Gejman PV, Hall AS, Hamsten A, Huikuri HV, Iribarren C, Kähönen M, Kaprio J, Kathiresan S, Kiemeney L, Kocher T, Launer LJ, Lehtimäki T, Melander O, Mosley TH Jr, Musk AW, Nieminen MS, O'Donnell CJ, Ohlsson C, Oostra B, Palmer LJ, Raitakari O, Ridker PM, Rioux JD, Rissanen A, Rivolta C, Schunkert H, Shuldiner AR, Siscovick DS, Stumvoll M, Tönjes A, Tuomilehto J, van Ommen GJ, Viikari J, Heath AC, Martin NG, Montgomery GW, Province MA, Kayser M, Arnold AM, Atwood LD, Boerwinkle E, Chanock SJ, Deloukas P, Gieger C, Grönberg H, Hall P, Hattersley AT, Hengstenberg C, Hoffman W, Lathrop GM, Salomaa V, Schreiber S, Uda M, Waterworth D, Wright AF, Assimes TL, Barroso I, Hofman A, Mohlke KL, Boomsma DI, Caulfield MJ, Cupples LA, Erdmann J, Fox CS, Gudnason V, Gyllensten U, Harris TB, Hayes RB, Jarvelin MR, Mooser V, Munroe PB, Ouwehand WH, Penninx BW, Pramstaller PP, Quertermous T, Rudan I, Samani NJ, Spector TD, Völzke H, Watkins H, Wilson JF, Groop LC, Haritunians T, Hu FB, Kaplan RC, Metspalu A, North KE, Schlessinger D, Wareham NJ, Hunter DJ, O'Connell JR, Strachan DP, Wichmann HE, Borecki IB, van Duijn CM, Schadt EE, Thorsteinsdottir U, Peltonen L, Uitterlinden AG, Visscher PM, Chatterjee N, Loos RJ, Boehnke M, McCarthy MI, Ingelsson E, Lindgren CM, Abecasis GR, Stefansson K, Frayling TM, Hirschhorn JN.

Nature. 2010 Oct 14;467(7317):832-8. doi: 10.1038/nature09410. Epub 2010 Sep 29.

3.

Height matters-from monogenic disorders to normal variation.

Durand C, Rappold GA.

Nat Rev Endocrinol. 2013 Mar;9(3):171-7. doi: 10.1038/nrendo.2012.251. Epub 2013 Jan 22. Review.

PMID:
23337954
4.

Genome-wide association studies of human growth traits.

Weedon MN.

Nestle Nutr Inst Workshop Ser. 2013;71:29-38. doi: 10.1159/000342541. Epub 2013 Jan 22. Review.

PMID:
23502136
5.

Identifying common genetic variants in blood pressure due to polygenic pleiotropy with associated phenotypes.

Andreassen OA, McEvoy LK, Thompson WK, Wang Y, Reppe S, Schork AJ, Zuber V, Barrett-Connor E, Gautvik K, Aukrust P, Karlsen TH, Djurovic S, Desikan RS, Dale AM; International Consortium for Blood Pressure Genome-Wide Association Studies, Genetic Factors for Osteoporosis Consortium.

Hypertension. 2014 Apr;63(4):819-26. doi: 10.1161/HYPERTENSIONAHA.113.02077. Epub 2014 Jan 6.

6.

Genome-wide association studies: potential next steps on a genetic journey.

McCarthy MI, Hirschhorn JN.

Hum Mol Genet. 2008 Oct 15;17(R2):R156-65. doi: 10.1093/hmg/ddn289. Review.

7.

Common inherited variation in mitochondrial genes is not enriched for associations with type 2 diabetes or related glycemic traits.

Segrè AV; DIAGRAM Consortium; MAGIC investigators, Groop L, Mootha VK, Daly MJ, Altshuler D.

PLoS Genet. 2010 Aug 12;6(8). pii: e1001058. doi: 10.1371/journal.pgen.1001058.

8.

Novel biological insights emerging from genetic studies of type 2 diabetes and related metabolic traits.

De Silva NM, Frayling TM.

Curr Opin Lipidol. 2010 Feb;21(1):44-50. doi: 10.1097/MOL.0b013e328334fdb6. Review.

PMID:
19956073
9.

Genome-wide association studies for common diseases and complex traits.

Hirschhorn JN, Daly MJ.

Nat Rev Genet. 2005 Feb;6(2):95-108. Review.

PMID:
15716906
10.

Genome-wide association studies in type 2 diabetes.

McCarthy MI, Zeggini E.

Curr Diab Rep. 2009 Apr;9(2):164-71. Review.

11.

The genetics of autism.

Muhle R, Trentacoste SV, Rapin I.

Pediatrics. 2004 May;113(5):e472-86. Review.

PMID:
15121991
12.

Common genetic variation and human traits.

Goldstein DB.

N Engl J Med. 2009 Apr 23;360(17):1696-8. doi: 10.1056/NEJMp0806284. Epub 2009 Apr 15. No abstract available.

PMID:
19369660
13.

Common disorders are quantitative traits.

Plomin R, Haworth CM, Davis OS.

Nat Rev Genet. 2009 Dec;10(12):872-8. doi: 10.1038/nrg2670. Epub 2009 Oct 27. Review.

PMID:
19859063
14.

A population genetic signal of polygenic adaptation.

Berg JJ, Coop G.

PLoS Genet. 2014 Aug 7;10(8):e1004412. doi: 10.1371/journal.pgen.1004412. eCollection 2014 Aug.

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17.

Agreement among type 2 diabetes linkage studies but a poor correlation with results from genome-wide association studies.

Lillioja S, Wilton A.

Diabetologia. 2009 Jun;52(6):1061-74. doi: 10.1007/s00125-009-1324-9. Epub 2009 Mar 19.

PMID:
19296077
18.

Evaluating empirical bounds on complex disease genetic architecture.

Agarwala V, Flannick J, Sunyaev S; GoT2D Consortium, Altshuler D.

Nat Genet. 2013 Dec;45(12):1418-27. doi: 10.1038/ng.2804. Epub 2013 Oct 20.

19.

Genetics of type 2 diabetes and potential clinical implications.

Kwak SH, Park KS.

Arch Pharm Res. 2013 Feb;36(2):167-77. doi: 10.1007/s12272-013-0021-x. Epub 2013 Feb 2. Review.

PMID:
23377708
20.

Analysis of 32 common susceptibility genetic variants and their combined effect in predicting risk of Type 2 diabetes and related traits in Indians.

Janipalli CS, Kumar MV, Vinay DG, Sandeep MN, Bhaskar S, Kulkarni SR, Aruna M, Joglekar CV, Priyadharshini S, Maheshwari N, Yajnik CS, Chandak GR.

Diabet Med. 2012 Jan;29(1):121-7. doi: 10.1111/j.1464-5491.2011.03438.x.

PMID:
21913964
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