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Results: 1 to 20 of 146

1.

Nostocyclopeptide-M1: a potent, nontoxic inhibitor of the hepatocyte drug transporters OATP1B3 and OATP1B1.

Herfindal L, Myhren L, Kleppe R, Krakstad C, Selheim F, Jokela J, Sivonen K, Døskeland SO.

Mol Pharm. 2011 Apr 4;8(2):360-7. doi: 10.1021/mp1002224. Epub 2011 Jan 24.

PMID:
21214185
[PubMed - indexed for MEDLINE]
2.

Potent cytotoxicity of the phosphatase inhibitor microcystin LR and microcystin analogues in OATP1B1- and OATP1B3-expressing HeLa cells.

Monks NR, Liu S, Xu Y, Yu H, Bendelow AS, Moscow JA.

Mol Cancer Ther. 2007 Feb;6(2):587-98.

PMID:
17308056
[PubMed - indexed for MEDLINE]
Free Article
3.

Inhibition of hepatic uptake transporters by flavonoids.

Mandery K, Balk B, Bujok K, Schmidt I, Fromm MF, Glaeser H.

Eur J Pharm Sci. 2012 May 12;46(1-2):79-85. doi: 10.1016/j.ejps.2012.02.014. Epub 2012 Feb 28.

PMID:
22394605
[PubMed - indexed for MEDLINE]
4.

Involvement of mitogen-activated protein kinase signaling pathways in microcystin-LR-induced apoptosis after its selective uptake mediated by OATP1B1 and OATP1B3.

Komatsu M, Furukawa T, Ikeda R, Takumi S, Nong Q, Aoyama K, Akiyama S, Keppler D, Takeuchi T.

Toxicol Sci. 2007 Jun;97(2):407-16. Epub 2007 Mar 16.

PMID:
17369605
[PubMed - indexed for MEDLINE]
Free Article
5.

Substrate-dependent drug-drug interactions between gemfibrozil, fluvastatin and other organic anion-transporting peptide (OATP) substrates on OATP1B1, OATP2B1, and OATP1B3.

Noé J, Portmann R, Brun ME, Funk C.

Drug Metab Dispos. 2007 Aug;35(8):1308-14. Epub 2007 Apr 30.

PMID:
17470528
[PubMed - indexed for MEDLINE]
Free Article
6.

Isolation of modulators of the liver-specific organic anion-transporting polypeptides (OATPs) 1B1 and 1B3 from Rollinia emarginata Schlecht (Annonaceae).

Roth M, Araya JJ, Timmermann BN, Hagenbuch B.

J Pharmacol Exp Ther. 2011 Nov;339(2):624-32. doi: 10.1124/jpet.111.184564. Epub 2011 Aug 16.

PMID:
21846839
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Influence of non-steroidal anti-inflammatory drugs on organic anion transporting polypeptide (OATP) 1B1- and OATP1B3-mediated drug transport.

Kindla J, Müller F, Mieth M, Fromm MF, König J.

Drug Metab Dispos. 2011 Jun;39(6):1047-53. doi: 10.1124/dmd.110.037622. Epub 2011 Mar 9.

PMID:
21389119
[PubMed - indexed for MEDLINE]
Free Article
8.

Fluorescence-based assays for the assessment of drug interaction with the human transporters OATP1B1 and OATP1B3.

Bednarczyk D.

Anal Biochem. 2010 Oct 1;405(1):50-8. doi: 10.1016/j.ab.2010.06.012. Epub 2010 Jun 9.

PMID:
20540932
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

The role of organic anion transporting polypeptides (OATPs/SLCOs) in the toxicity of different microcystin congeners in vitro: a comparison of primary human hepatocytes and OATP-transfected HEK293 cells.

Fischer A, Hoeger SJ, Stemmer K, Feurstein DJ, Knobeloch D, Nussler A, Dietrich DR.

Toxicol Appl Pharmacol. 2010 May 15;245(1):9-20. doi: 10.1016/j.taap.2010.02.006. Epub 2010 Feb 17.

PMID:
20171238
[PubMed - indexed for MEDLINE]
10.

Screening of antibiotics that interact with organic anion-transporting polypeptides 1B1 and 1B3 using fluorescent probes.

Yamaguchi H, Takeuchi T, Okada M, Kobayashi M, Unno M, Abe T, Goto J, Hishinuma T, Shimada M, Mano N.

Biol Pharm Bull. 2011;34(3):389-95.

PMID:
21372390
[PubMed - indexed for MEDLINE]
Free Article
11.

Long-lasting inhibitory effects of cyclosporin A, but not tacrolimus, on OATP1B1- and OATP1B3-mediated uptake.

Shitara Y, Takeuchi K, Nagamatsu Y, Wada S, Sugiyama Y, Horie T.

Drug Metab Pharmacokinet. 2012;27(4):368-78. Epub 2012 Jan 13.

PMID:
22240838
[PubMed - indexed for MEDLINE]
Free Article
12.

Involvement of transporters in the hepatic uptake and biliary excretion of valsartan, a selective antagonist of the angiotensin II AT1-receptor, in humans.

Yamashiro W, Maeda K, Hirouchi M, Adachi Y, Hu Z, Sugiyama Y.

Drug Metab Dispos. 2006 Jul;34(7):1247-54. Epub 2006 Apr 19.

PMID:
16624871
[PubMed - indexed for MEDLINE]
Free Article
13.

OATP1B1, OATP1B3, and mrp2 are involved in hepatobiliary transport of olmesartan, a novel angiotensin II blocker.

Nakagomi-Hagihara R, Nakai D, Kawai K, Yoshigae Y, Tokui T, Abe T, Ikeda T.

Drug Metab Dispos. 2006 May;34(5):862-9. Epub 2006 Feb 24.

PMID:
16501004
[PubMed - indexed for MEDLINE]
Free Article
14.

Drug-drug interaction between pitavastatin and various drugs via OATP1B1.

Hirano M, Maeda K, Shitara Y, Sugiyama Y.

Drug Metab Dispos. 2006 Jul;34(7):1229-36. Epub 2006 Apr 4.

PMID:
16595711
[PubMed - indexed for MEDLINE]
Free Article
15.

A novel cyanobacterial nostocyclopeptide is a potent antitoxin against microcystins.

Jokela J, Herfindal L, Wahlsten M, Permi P, Selheim F, Vasconçelos V, Døskeland SO, Sivonen K.

Chembiochem. 2010 Jul 26;11(11):1594-9. doi: 10.1002/cbic.201000179.

PMID:
20575133
[PubMed - indexed for MEDLINE]
16.

Further characterization of the electrogenicity and pH sensitivity of the human organic anion-transporting polypeptides OATP1B1 and OATP1B3.

Martinez-Becerra P, Briz O, Romero MR, Macias RI, Perez MJ, Sancho-Mateo C, Lostao MP, Fernandez-Abalos JM, Marin JJ.

Mol Pharmacol. 2011 Mar;79(3):596-607. doi: 10.1124/mol.110.069971. Epub 2010 Dec 20.

PMID:
21173039
[PubMed - indexed for MEDLINE]
Free Article
17.

Contribution of organic anion transporting polypeptide (OATP) 1B1 and OATP1B3 to hepatic uptake of nateglinide, and the prediction of drug-drug interactions via these transporters.

Takanohashi T, Kubo S, Arisaka H, Shinkai K, Ubukata K.

J Pharm Pharmacol. 2012 Feb;64(2):199-206. doi: 10.1111/j.2042-7158.2011.01389.x. Epub 2011 Nov 10.

PMID:
22221095
[PubMed - indexed for MEDLINE]
18.

Characterization of ursodeoxycholic and norursodeoxycholic acid as substrates of the hepatic uptake transporters OATP1B1, OATP1B3, OATP2B1 and NTCP.

König J, Klatt S, Dilger K, Fromm MF.

Basic Clin Pharmacol Toxicol. 2012 Aug;111(2):81-6. doi: 10.1111/j.1742-7843.2012.00865.x. Epub 2012 Mar 9.

PMID:
22333292
[PubMed - indexed for MEDLINE]
19.

Clinical importance of OATP1B1 and OATP1B3 in drug-drug interactions.

Shitara Y.

Drug Metab Pharmacokinet. 2011 Jun;26(3):220-7. doi: 10.2133/dmpk.DMPK-10-RV-094. Epub 2011 Feb 1. Review.

PMID:
21297316
[PubMed - indexed for MEDLINE]
Free Article
20.

Vectorial transport of enalapril by Oatp1a1/Mrp2 and OATP1B1 and OATP1B3/MRP2 in rat and human livers.

Liu L, Cui Y, Chung AY, Shitara Y, Sugiyama Y, Keppler D, Pang KS.

J Pharmacol Exp Ther. 2006 Jul;318(1):395-402. Epub 2006 Apr 20.

PMID:
16627748
[PubMed - indexed for MEDLINE]
Free Article
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