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Items: 1 to 20 of 95


Amyloid-β inhibits No-cGMP signaling in a CD36- and CD47-dependent manner.

Miller TW, Isenberg JS, Shih HB, Wang Y, Roberts DD.

PLoS One. 2010 Dec 22;5(12):e15686. doi: 10.1371/journal.pone.0015686.


Thrombospondin-1 inhibits nitric oxide signaling via CD36 by inhibiting myristic acid uptake.

Isenberg JS, Jia Y, Fukuyama J, Switzer CH, Wink DA, Roberts DD.

J Biol Chem. 2007 May 25;282(21):15404-15. Epub 2007 Apr 5.


CD47 is necessary for inhibition of nitric oxide-stimulated vascular cell responses by thrombospondin-1.

Isenberg JS, Ridnour LA, Dimitry J, Frazier WA, Wink DA, Roberts DD.

J Biol Chem. 2006 Sep 8;281(36):26069-80. Epub 2006 Jul 11.


A cell surface receptor complex for fibrillar beta-amyloid mediates microglial activation.

Bamberger ME, Harris ME, McDonald DR, Husemann J, Landreth GE.

J Neurosci. 2003 Apr 1;23(7):2665-74.


Stimulation of soluble guanylate cyclase slows progression in anti-thy1-induced chronic glomerulosclerosis.

Wang Y, Krämer S, Loof T, Martini S, Kron S, Kawachi H, Shimizu F, Neumayer HH, Peters H.

Kidney Int. 2005 Jul;68(1):47-61.


Differential interactions of thrombospondin-1, -2, and -4 with CD47 and effects on cGMP signaling and ischemic injury responses.

Isenberg JS, Annis DS, Pendrak ML, Ptaszynska M, Frazier WA, Mosher DF, Roberts DD.

J Biol Chem. 2009 Jan 9;284(2):1116-25. doi: 10.1074/jbc.M804860200. Epub 2008 Nov 11.


Thrombospondin-1 inhibits VEGF receptor-2 signaling by disrupting its association with CD47.

Kaur S, Martin-Manso G, Pendrak ML, Garfield SH, Isenberg JS, Roberts DD.

J Biol Chem. 2010 Dec 10;285(50):38923-32. doi: 10.1074/jbc.M110.172304. Epub 2010 Oct 5.


Aging modulates nitric oxide synthesis and cGMP levels in hippocampus and cerebellum. Effects of amyloid beta peptide.

Chalimoniuk M, Strosznajder JB.

Mol Chem Neuropathol. 1998 Aug-Dec;35(1-3):77-95.


CD36, a class B scavenger receptor, is expressed on microglia in Alzheimer's disease brains and can mediate production of reactive oxygen species in response to beta-amyloid fibrils.

Coraci IS, Husemann J, Berman JW, Hulette C, Dufour JH, Campanella GK, Luster AD, Silverstein SC, El-Khoury JB.

Am J Pathol. 2002 Jan;160(1):101-12.


Fibrillar amyloid protein present in atheroma activates CD36 signal transduction.

Medeiros LA, Khan T, El Khoury JB, Pham CL, Hatters DM, Howlett GJ, Lopez R, O'Brien KD, Moore KJ.

J Biol Chem. 2004 Mar 12;279(11):10643-8. Epub 2003 Dec 29.


Thrombospondin-1-CD47 blockade and exogenous nitrite enhance ischemic tissue survival, blood flow and angiogenesis via coupled NO-cGMP pathway activation.

Isenberg JS, Shiva S, Gladwin M.

Nitric Oxide. 2009 Aug;21(1):52-62. doi: 10.1016/j.niox.2009.05.005. Epub 2009 May 27.


Thrombospondin-1 antagonizes nitric oxide-stimulated vascular smooth muscle cell responses.

Isenberg JS, Wink DA, Roberts DD.

Cardiovasc Res. 2006 Sep 1;71(4):785-93. Epub 2006 May 27.


Role of nitric oxide/cyclic GMP and cyclic AMP in beta3 adrenoceptor-chronotropic response.

Sterin-Borda L, Bernabeo G, Ganzinelli S, Joensen L, Borda E.

J Mol Cell Cardiol. 2006 Apr;40(4):580-8. Epub 2006 Feb 28.


Expression and activity of soluble guanylate cyclase in injury and repair of anti-thy1 glomerulonephritis.

Peters H, Wang Y, Loof T, Martini S, Kron S, Krämer S, Neumayer HH.

Kidney Int. 2004 Dec;66(6):2224-36.


Thrombospondin-1 inhibits endothelial cell responses to nitric oxide in a cGMP-dependent manner.

Isenberg JS, Ridnour LA, Perruccio EM, Espey MG, Wink DA, Roberts DD.

Proc Natl Acad Sci U S A. 2005 Sep 13;102(37):13141-6. Epub 2005 Sep 6.


Prostaglandin E2 stimulates angiogenesis by activating the nitric oxide/cGMP pathway in human umbilical vein endothelial cells.

Namkoong S, Lee SJ, Kim CK, Kim YM, Chung HT, Lee H, Han JA, Ha KS, Kwon YG, Kim YM.

Exp Mol Med. 2005 Dec 31;37(6):588-600.


A CD36-initiated signaling cascade mediates inflammatory effects of beta-amyloid.

Moore KJ, El Khoury J, Medeiros LA, Terada K, Geula C, Luster AD, Freeman MW.

J Biol Chem. 2002 Dec 6;277(49):47373-9. Epub 2002 Sep 17.

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