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Results: 1 to 20 of 85

1.

Detrimental effects of adenosine signaling in sickle cell disease.

Zhang Y, Dai Y, Wen J, Zhang W, Grenz A, Sun H, Tao L, Lu G, Alexander DC, Milburn MV, Carter-Dawson L, Lewis DE, Zhang W, Eltzschig HK, Kellems RE, Blackburn MR, Juneja HS, Xia Y.

Nat Med. 2011 Jan;17(1):79-86. doi: 10.1038/nm.2280. Epub 2010 Dec 19.

PMID:
21170046
[PubMed - indexed for MEDLINE]
2.

Adenosine signaling in normal and sickle erythrocytes and beyond.

Zhang Y, Xia Y.

Microbes Infect. 2012 Aug;14(10):863-73. doi: 10.1016/j.micinf.2012.05.005. Epub 2012 May 23. Review.

PMID:
22634345
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Adenosine receptor crossroads in sickle cell disease.

Gladwin MT.

Nat Med. 2011 Jan;17(1):38-40. doi: 10.1038/nm0111-38. No abstract available.

PMID:
21217677
[PubMed - indexed for MEDLINE]
4.

New insights into sickle cell disease: a disease of hypoxia.

Sun K, Xia Y.

Curr Opin Hematol. 2013 May;20(3):215-21. doi: 10.1097/MOH.0b013e32835f55f9. Review.

PMID:
23549375
[PubMed - indexed for MEDLINE]
5.

Excess adenosine in murine penile erectile tissues contributes to priapism via A2B adenosine receptor signaling.

Mi T, Abbasi S, Zhang H, Uray K, Chunn JL, Xia LW, Molina JG, Weisbrodt NW, Kellems RE, Blackburn MR, Xia Y.

J Clin Invest. 2008 Apr;118(4):1491-501. doi: 10.1172/JCI33467.

PMID:
18340377
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

In vivo demonstration of red cell-endothelial interaction, sickling and altered microvascular response to oxygen in the sickle transgenic mouse.

Kaul DK, Fabry ME, Costantini F, Rubin EM, Nagel RL.

J Clin Invest. 1995 Dec;96(6):2845-53.

PMID:
8675655
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Adenosine signaling, priapism and novel therapies.

Dai Y, Zhang Y, Phatarpekar P, Mi T, Zhang H, Blackburn MR, Xia Y.

J Sex Med. 2009 Mar;6 Suppl 3:292-301. doi: 10.1111/j.1743-6109.2008.01187.x. Review.

PMID:
19267852
[PubMed - indexed for MEDLINE]
8.

Antisickling property of fetal hemoglobin enhances nitric oxide bioavailability and ameliorates organ oxidative stress in transgenic-knockout sickle mice.

Dasgupta T, Fabry ME, Kaul DK.

Am J Physiol Regul Integr Comp Physiol. 2010 Feb;298(2):R394-402. doi: 10.1152/ajpregu.00611.2009. Epub 2009 Dec 9.

PMID:
20007516
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Senicapoc (ICA-17043): a potential therapy for the prevention and treatment of hemolysis-associated complications in sickle cell anemia.

Ataga KI, Stocker J.

Expert Opin Investig Drugs. 2009 Feb;18(2):231-9. doi: 10.1517/13543780802708011 . Review.

PMID:
19236269
[PubMed - indexed for MEDLINE]
10.

High expression of human beta S- and alpha-globins in transgenic mice: erythrocyte abnormalities, organ damage, and the effect of hypoxia.

Fabry ME, Costantini F, Pachnis A, Suzuka SM, Bank N, Aynedjian HS, Factor SM, Nagel RL.

Proc Natl Acad Sci U S A. 1992 Dec 15;89(24):12155-9.

PMID:
1465455
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Increased adenosine contributes to penile fibrosis, a dangerous feature of priapism, via A2B adenosine receptor signaling.

Wen J, Jiang X, Dai Y, Zhang Y, Tang Y, Sun H, Mi T, Phatarpekar PV, Kellems RE, Blackburn MR, Xia Y.

FASEB J. 2010 Mar;24(3):740-9. doi: 10.1096/fj.09-144147. Epub 2009 Oct 26.

PMID:
19858092
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Second generation knockout sickle mice: the effect of HbF.

Fabry ME, Suzuka SM, Weinberg RS, Lawrence C, Factor SM, Gilman JG, Costantini F, Nagel RL.

Blood. 2001 Jan 15;97(2):410-8.

PMID:
11154217
[PubMed - indexed for MEDLINE]
Free Article
13.

A second generation transgenic mouse model expressing both hemoglobin S (HbS) and HbS-Antilles results in increased phenotypic severity.

Fabry ME, Sengupta A, Suzuka SM, Costantini F, Rubin EM, Hofrichter J, Christoph G, Manci E, Culberson D, Factor SM, Nagel RL.

Blood. 1995 Sep 15;86(6):2419-28.

PMID:
7662990
[PubMed - indexed for MEDLINE]
Free Article
14.

Human sickle cell blood modulates endothelial heme oxygenase activity: effects on vascular adhesion and reactivity.

Bains SK, Foresti R, Howard J, Atwal S, Green CJ, Motterlini R.

Arterioscler Thromb Vasc Biol. 2010 Feb;30(2):305-12. doi: 10.1161/ATVBAHA.109.196360. Epub 2009 Dec 3.

PMID:
19965783
[PubMed - indexed for MEDLINE]
Free Article
15.

A2B adenosine receptor-mediated induction of IL-6 promotes CKD.

Dai Y, Zhang W, Wen J, Zhang Y, Kellems RE, Xia Y.

J Am Soc Nephrol. 2011 May;22(5):890-901. doi: 10.1681/ASN.2010080890. Epub 2011 Apr 21.

PMID:
21511827
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

A recombinant human hemoglobin with anti-sickling properties greater than fetal hemoglobin.

Levasseur DN, Ryan TM, Reilly MP, McCune SL, Asakura T, Townes TM.

J Biol Chem. 2004 Jun 25;279(26):27518-24. Epub 2004 Apr 14.

PMID:
15084588
[PubMed - indexed for MEDLINE]
Free Article
17.

Towards a transgenic mouse model of sickle cell disease: hemoglobin SAD.

Trudel M, Saadane N, Garel MC, Bardakdjian-Michau J, Blouquit Y, Guerquin-Kern JL, Rouyer-Fessard P, Vidaud D, Pachnis A, Roméo PH, et al.

EMBO J. 1991 Nov;10(11):3157-65.

PMID:
1915288
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Enhanced airway inflammation and remodeling in adenosine deaminase-deficient mice lacking the A2B adenosine receptor.

Zhou Y, Mohsenin A, Morschl E, Young HW, Molina JG, Ma W, Sun CX, Martinez-Valdez H, Blackburn MR.

J Immunol. 2009 Jun 15;182(12):8037-46. doi: 10.4049/jimmunol.0900515.

PMID:
19494329
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Red blood cell membrane and density changes under ambient and hypoxic conditions in transgenic mice producing human sickle hemoglobin.

Reilly MP, Chomo MJ, Obata K, Asakura T.

Exp Hematol. 1994 Jun;22(6):501-9.

PMID:
8187846
[PubMed - indexed for MEDLINE]
20.

Reperfusion injury pathophysiology in sickle transgenic mice.

Osarogiagbon UR, Choong S, Belcher JD, Vercellotti GM, Paller MS, Hebbel RP.

Blood. 2000 Jul 1;96(1):314-20.

PMID:
10891467
[PubMed - indexed for MEDLINE]
Free Article

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