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Results: 1 to 20 of 154

1.

Aptamer-based multiplexed proteomic technology for biomarker discovery.

Gold L, Ayers D, Bertino J, Bock C, Bock A, Brody EN, Carter J, Dalby AB, Eaton BE, Fitzwater T, Flather D, Forbes A, Foreman T, Fowler C, Gawande B, Goss M, Gunn M, Gupta S, Halladay D, Heil J, Heilig J, Hicke B, Husar G, Janjic N, Jarvis T, Jennings S, Katilius E, Keeney TR, Kim N, Koch TH, Kraemer S, Kroiss L, Le N, Levine D, Lindsey W, Lollo B, Mayfield W, Mehan M, Mehler R, Nelson SK, Nelson M, Nieuwlandt D, Nikrad M, Ochsner U, Ostroff RM, Otis M, Parker T, Pietrasiewicz S, Resnicow DI, Rohloff J, Sanders G, Sattin S, Schneider D, Singer B, Stanton M, Sterkel A, Stewart A, Stratford S, Vaught JD, Vrkljan M, Walker JJ, Watrobka M, Waugh S, Weiss A, Wilcox SK, Wolfson A, Wolk SK, Zhang C, Zichi D.

PLoS One. 2010 Dec 7;5(12):e15004. doi: 10.1371/journal.pone.0015004.

PMID:
21165148
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Highly multiplexed proteomic platform for biomarker discovery, diagnostics, and therapeutics.

Mehan MR, Ostroff R, Wilcox SK, Steele F, Schneider D, Jarvis TC, Baird GS, Gold L, Janjic N.

Adv Exp Med Biol. 2013;735:283-300. Review.

PMID:
23402035
[PubMed - indexed for MEDLINE]
3.

High-content affinity-based proteomics: unlocking protein biomarker discovery.

Brody EN, Gold L, Lawn RM, Walker JJ, Zichi D.

Expert Rev Mol Diagn. 2010 Nov;10(8):1013-22. doi: 10.1586/erm.10.89. Review.

PMID:
21080818
[PubMed - indexed for MEDLINE]
4.

Unlocking biomarker discovery: large scale application of aptamer proteomic technology for early detection of lung cancer.

Ostroff RM, Bigbee WL, Franklin W, Gold L, Mehan M, Miller YE, Pass HI, Rom WN, Siegfried JM, Stewart A, Walker JJ, Weissfeld JL, Williams S, Zichi D, Brody EN.

PLoS One. 2010 Dec 7;5(12):e15003. doi: 10.1371/journal.pone.0015003.

PMID:
21170350
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Quantitative selection and parallel characterization of aptamers.

Cho M, Soo Oh S, Nie J, Stewart R, Eisenstein M, Chambers J, Marth JD, Walker F, Thomson JA, Soh HT.

Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):18460-5. doi: 10.1073/pnas.1315866110. Epub 2013 Oct 28.

PMID:
24167271
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Identification of cis-regulatory variation influencing protein abundance levels in human plasma.

Lourdusamy A, Newhouse S, Lunnon K, Proitsi P, Powell J, Hodges A, Nelson SK, Stewart A, Williams S, Kloszewska I, Mecocci P, Soininen H, Tsolaki M, Vellas B, Lovestone S; AddNeuroMed Consortium, Dobson R; Alzheimer's Disease Neuroimaging Initiative.

Hum Mol Genet. 2012 Aug 15;21(16):3719-26. Epub 2012 May 16.

PMID:
22595970
[PubMed - indexed for MEDLINE]
Free Article
7.

Aptamer-facilitated biomarker discovery (AptaBiD).

Berezovski MV, Lechmann M, Musheev MU, Mak TW, Krylov SN.

J Am Chem Soc. 2008 Jul 16;130(28):9137-43. doi: 10.1021/ja801951p. Epub 2008 Jun 18.

PMID:
18558676
[PubMed - indexed for MEDLINE]
8.

Clinical proteomics: from biomarker discovery and cell signaling profiles to individualized personal therapy.

Calvo KR, Liotta LA, Petricoin EF.

Biosci Rep. 2005 Feb-Apr;25(1-2):107-25. Review.

PMID:
16222423
[PubMed - indexed for MEDLINE]
Free Article
9.

Age-dependent changes in the cerebrospinal fluid proteome by slow off-rate modified aptamer array.

Baird GS, Nelson SK, Keeney TR, Stewart A, Williams S, Kraemer S, Peskind ER, Montine TJ.

Am J Pathol. 2012 Feb;180(2):446-56. doi: 10.1016/j.ajpath.2011.10.024. Epub 2011 Nov 26.

PMID:
22122984
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Application of proteomic technologies for prostate cancer detection, prognosis, and tailored therapy.

Fredolini C, Liotta LA, Petricoin EF.

Crit Rev Clin Lab Sci. 2010 May-Jun;47(3):125-38. doi: 10.3109/10408363.2010.503558. Epub 2010 Sep 21. Review.

PMID:
20858067
[PubMed - indexed for MEDLINE]
11.

The discovery and development of proteomic safety biomarkers for the detection of drug-induced liver toxicity.

Amacher DE.

Toxicol Appl Pharmacol. 2010 May 15;245(1):134-42. doi: 10.1016/j.taap.2010.02.011. Epub 2010 Feb 26. Review.

PMID:
20219512
[PubMed - indexed for MEDLINE]
12.

Massively parallel interrogation of aptamer sequence, structure and function.

Fischer NO, Tok JB, Tarasow TM.

PLoS One. 2008 Jul 16;3(7):e2720. doi: 10.1371/journal.pone.0002720.

PMID:
18628955
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Aptamers and the next generation of diagnostic reagents.

Thiviyanathan V, Gorenstein DG.

Proteomics Clin Appl. 2012 Dec;6(11-12):563-73. doi: 10.1002/prca.201200042. Review.

PMID:
23090891
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Activity-based protein profiling: applications to biomarker discovery, in vivo imaging and drug discovery.

Berger AB, Vitorino PM, Bogyo M.

Am J Pharmacogenomics. 2004;4(6):371-81. Review.

PMID:
15651898
[PubMed - indexed for MEDLINE]
15.

The stability of the circulating human proteome to variations in sample collection and handling procedures measured with an aptamer-based proteomics array.

Ostroff R, Foreman T, Keeney TR, Stratford S, Walker JJ, Zichi D.

J Proteomics. 2010 Jan 3;73(3):649-66. doi: 10.1016/j.jprot.2009.09.004. Epub 2009 Sep 13.

PMID:
19755178
[PubMed - indexed for MEDLINE]
16.

Mass spectrometric discovery and selective reaction monitoring (SRM) of putative protein biomarker candidates in first trimester Trisomy 21 maternal serum.

Lopez MF, Kuppusamy R, Sarracino DA, Prakash A, Athanas M, Krastins B, Rezai T, Sutton JN, Peterman S, Nicolaides K.

J Proteome Res. 2011 Jan 7;10(1):133-42. doi: 10.1021/pr100153j. Epub 2010 Jun 4.

PMID:
20499897
[PubMed - indexed for MEDLINE]
17.

Clinical proteomics for cancer biomarker discovery and therapeutic targeting.

Krieg RC, Paweletz CP, Liotta LA, Petricoin EF 3rd.

Technol Cancer Res Treat. 2002 Aug;1(4):263-72. Review.

PMID:
12625785
[PubMed - indexed for MEDLINE]
18.

An automated and multiplexed method for high throughput peptide immunoaffinity enrichment and multiple reaction monitoring mass spectrometry-based quantification of protein biomarkers.

Whiteaker JR, Zhao L, Anderson L, Paulovich AG.

Mol Cell Proteomics. 2010 Jan;9(1):184-96. doi: 10.1074/mcp.M900254-MCP200. Epub 2009 Oct 20.

PMID:
19843560
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Determination of burn patient outcome by large-scale quantitative discovery proteomics.

Finnerty CC, Jeschke MG, Qian WJ, Kaushal A, Xiao W, Liu T, Gritsenko MA, Moore RJ, Camp DG 2nd, Moldawer LL, Elson C, Schoenfeld D, Gamelli R, Gibran N, Klein M, Arnoldo B, Remick D, Smith RD, Davis R, Tompkins RG, Herndon DN; Investigators of the Inflammation and the Host Response Glue Grant.

Crit Care Med. 2013 Jun;41(6):1421-34. doi: 10.1097/CCM.0b013e31827c072e.

PMID:
23507713
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Plasma-derived microparticles for biomarker discovery.

Smalley DM, Ley K.

Clin Lab. 2008;54(3-4):67-79. Review.

PMID:
18630736
[PubMed - indexed for MEDLINE]

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