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Results: 1 to 20 of 118

1.

The substrate of Greatwall kinase, Arpp19, controls mitosis by inhibiting protein phosphatase 2A.

Gharbi-Ayachi A, Labbé JC, Burgess A, Vigneron S, Strub JM, Brioudes E, Van-Dorsselaer A, Castro A, Lorca T.

Science. 2010 Dec 17;330(6011):1673-7. doi: 10.1126/science.1197048.

PMID:
21164014
[PubMed - indexed for MEDLINE]
Free Article
2.

Greatwall phosphorylates an inhibitor of protein phosphatase 2A that is essential for mitosis.

Mochida S, Maslen SL, Skehel M, Hunt T.

Science. 2010 Dec 17;330(6011):1670-3. doi: 10.1126/science.1195689.

PMID:
21164013
[PubMed - indexed for MEDLINE]
Free Article
3.

Constant regulation of both the MPF amplification loop and the Greatwall-PP2A pathway is required for metaphase II arrest and correct entry into the first embryonic cell cycle.

Lorca T, Bernis C, Vigneron S, Burgess A, Brioudes E, Labbé JC, Castro A.

J Cell Sci. 2010 Jul 1;123(Pt 13):2281-91. doi: 10.1242/jcs.064527.

PMID:
20554897
[PubMed - indexed for MEDLINE]
Free Article
4.

The phosphorylation of ARPP19 by Greatwall renders the auto-amplification of MPF independently of PKA in Xenopus oocytes.

Dupré A, Buffin E, Roustan C, Nairn AC, Jessus C, Haccard O.

J Cell Sci. 2013 Sep 1;126(Pt 17):3916-26. doi: 10.1242/jcs.126599. Epub 2013 Jun 18.

PMID:
23781026
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The Greatwall kinase: a new pathway in the control of the cell cycle.

Lorca T, Castro A.

Oncogene. 2013 Jan 31;32(5):537-43. doi: 10.1038/onc.2012.79. Epub 2012 Apr 2. Review.

PMID:
22469975
[PubMed - indexed for MEDLINE]
6.

PP2A/B55 and Fcp1 regulate Greatwall and Ensa dephosphorylation during mitotic exit.

Hégarat N, Vesely C, Vinod PK, Ocasio C, Peter N, Gannon J, Oliver AW, Novák B, Hochegger H.

PLoS Genet. 2014 Jan;10(1):e1004004. doi: 10.1371/journal.pgen.1004004. Epub 2014 Jan 2. Erratum in: PLoS Genet. 2014 Feb;10(2):e1004259.

PMID:
24391510
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the cyclin B-Cdc2/PP2A balance.

Burgess A, Vigneron S, Brioudes E, Labbé JC, Lorca T, Castro A.

Proc Natl Acad Sci U S A. 2010 Jul 13;107(28):12564-9. doi: 10.1073/pnas.0914191107. Epub 2010 Jun 10.

PMID:
20538976
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Greatwall kinase, ARPP-19 and protein phosphatase 2A: shifting the mitosis paradigm.

Haccard O, Jessus C.

Results Probl Cell Differ. 2011;53:219-34. doi: 10.1007/978-3-642-19065-0_11. Review.

PMID:
21630148
[PubMed - indexed for MEDLINE]
9.

Regulation of Greatwall kinase during Xenopus oocyte maturation.

Yamamoto TM, Blake-Hodek K, Williams BC, Lewellyn AL, Goldberg ML, Maller JL.

Mol Biol Cell. 2011 Jul 1;22(13):2157-64. doi: 10.1091/mbc.E11-01-0008. Epub 2011 May 5.

PMID:
21551066
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Greatwall maintains mitosis through regulation of PP2A.

Vigneron S, Brioudes E, Burgess A, Labbé JC, Lorca T, Castro A.

EMBO J. 2009 Sep 16;28(18):2786-93. doi: 10.1038/emboj.2009.228. Epub 2009 Aug 13.

PMID:
19680222
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Cell biology. Enforcing the Greatwall in mitosis.

Virshup DM, Kaldis P.

Science. 2010 Dec 17;330(6011):1638-9. doi: 10.1126/science.1199898. No abstract available.

PMID:
21164006
[PubMed - indexed for MEDLINE]
12.

Cyclin B-Cdk1 inhibits protein phosphatase PP2A-B55 via a Greatwall kinase-independent mechanism.

Okumura E, Morita A, Wakai M, Mochida S, Hara M, Kishimoto T.

J Cell Biol. 2014 Mar 17;204(6):881-9. doi: 10.1083/jcb.201307160. Epub 2014 Mar 10.

PMID:
24616226
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

The M phase kinase Greatwall (Gwl) promotes inactivation of PP2A/B55delta, a phosphatase directed against CDK phosphosites.

Castilho PV, Williams BC, Mochida S, Zhao Y, Goldberg ML.

Mol Biol Cell. 2009 Nov;20(22):4777-89. doi: 10.1091/mbc.E09-07-0643. Epub 2009 Sep 30.

PMID:
19793917
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Regulated activity of PP2A-B55 delta is crucial for controlling entry into and exit from mitosis in Xenopus egg extracts.

Mochida S, Ikeo S, Gannon J, Hunt T.

EMBO J. 2009 Sep 16;28(18):2777-85. doi: 10.1038/emboj.2009.238. Epub 2009 Aug 20.

PMID:
19696736
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Protein phosphatase 2A controls the order and dynamics of cell-cycle transitions.

Krasinska L, Domingo-Sananes MR, Kapuy O, Parisis N, Harker B, Moorhead G, Rossignol M, Novák B, Fisher D.

Mol Cell. 2011 Nov 4;44(3):437-50. doi: 10.1016/j.molcel.2011.10.007.

PMID:
22055189
[PubMed - indexed for MEDLINE]
Free Article
16.

On the regulation of protein phosphatase 2A and its role in controlling entry into and exit from mitosis.

Hunt T.

Adv Biol Regul. 2013 May;53(2):173-8. doi: 10.1016/j.jbior.2013.04.001. Epub 2013 Apr 29. Review.

PMID:
23672858
[PubMed - indexed for MEDLINE]
17.

Dynamic regulation of Emi2 by Emi2-bound Cdk1/Plk1/CK1 and PP2A-B56 in meiotic arrest of Xenopus eggs.

Isoda M, Sako K, Suzuki K, Nishino K, Nakajo N, Ohe M, Ezaki T, Kanemori Y, Inoue D, Ueno H, Sagata N.

Dev Cell. 2011 Sep 13;21(3):506-19. doi: 10.1016/j.devcel.2011.06.029. Epub 2011 Aug 25.

PMID:
21871841
[PubMed - indexed for MEDLINE]
Free Article
18.

Budding yeast greatwall and endosulfines control activity and spatial regulation of PP2A(Cdc55) for timely mitotic progression.

Juanes MA, Khoueiry R, Kupka T, Castro A, Mudrak I, Ogris E, Lorca T, Piatti S.

PLoS Genet. 2013;9(7):e1003575. doi: 10.1371/journal.pgen.1003575. Epub 2013 Jul 4.

PMID:
23861665
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Dephosphorylation of the inhibitory phosphorylation site S287 in Xenopus Cdc25C by protein phosphatase-2A is inhibited by 14-3-3 binding.

Hutchins JR, Dikovskaya D, Clarke PR.

FEBS Lett. 2002 Sep 25;528(1-3):267-71.

PMID:
12297318
[PubMed - indexed for MEDLINE]
20.

Phosphorylation and activation of human cdc25-C by cdc2--cyclin B and its involvement in the self-amplification of MPF at mitosis.

Hoffmann I, Clarke PR, Marcote MJ, Karsenti E, Draetta G.

EMBO J. 1993 Jan;12(1):53-63.

PMID:
8428594
[PubMed - indexed for MEDLINE]
Free PMC Article

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