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Items: 1 to 20 of 71

1.

Regulation of cell death by c-FLIP phosphorylation.

Asaoka T, Kaunisto A, Eriksson JE.

Adv Exp Med Biol. 2011;691:625-30. doi: 10.1007/978-1-4419-6612-4_66. No abstract available.

PMID:
21153369
2.

PKC-mediated phosphorylation regulates c-FLIP ubiquitylation and stability.

Kaunisto A, Kochin V, Asaoka T, Mikhailov A, Poukkula M, Meinander A, Eriksson JE.

Cell Death Differ. 2009 Sep;16(9):1215-26. doi: 10.1038/cdd.2009.35. Epub 2009 Apr 3.

3.

Mathematical modeling identified c-FLIP as an apoptotic switch in death receptor induced apoptosis.

Han L, Zhao Y, Jia X.

Apoptosis. 2008 Oct;13(10):1198-204. doi: 10.1007/s10495-008-0252-3.

PMID:
18726189
4.

Identification of c-FLIP(L) and c-FLIP(S) as critical regulators of death receptor-induced apoptosis in pancreatic cancer cells.

Haag C, Stadel D, Zhou S, Bachem MG, Möller P, Debatin KM, Fulda S.

Gut. 2011 Feb;60(2):225-37. doi: 10.1136/gut.2009.202325. Epub 2010 Sep 28.

PMID:
20876774
5.

Mutational analyses of c-FLIPR, the only murine short FLIP isoform, reveal requirements for DISC recruitment.

Ueffing N, Keil E, Freund C, Kühne R, Schulze-Osthoff K, Schmitz I.

Cell Death Differ. 2008 Apr;15(4):773-82. doi: 10.1038/sj.cdd.4402314. Epub 2008 Jan 25.

6.

C-FLIP promotes the motility of cancer cells by activating FAK and ERK, and increasing MMP-9 expression.

Park D, Shim E, Kim Y, Kim YM, Lee H, Choe J, Kang D, Lee YS, Jeoung D.

Mol Cells. 2008 Apr 30;25(2):184-95. Epub 2008 Mar 28.

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9.

Activation-induced degradation of FLIP(L) is mediated via the phosphatidylinositol 3-kinase/Akt signaling pathway in macrophages.

Shi B, Tran T, Sobkoviak R, Pope RM.

J Biol Chem. 2009 May 22;284(21):14513-23. doi: 10.1074/jbc.M807918200. Epub 2009 Apr 1.

10.

Cisplatin induces p53-dependent FLICE-like inhibitory protein ubiquitination in ovarian cancer cells.

Abedini MR, Muller EJ, Brun J, Bergeron R, Gray DA, Tsang BK.

Cancer Res. 2008 Jun 15;68(12):4511-7. doi: 10.1158/0008-5472.CAN-08-0673.

12.
13.

FLIP as an anti-cancer therapeutic target.

Yang JK.

Yonsei Med J. 2008 Feb 29;49(1):19-27. doi: 10.3349/ymj.2008.49.1.19. Review.

14.

Nuclear localization of c-FLIP-L and its regulation of AP-1 activity.

Zhang J, Chen Y, Huang Q, Cheng W, Kang Y, Shu L, Yin W, Hua ZC.

Int J Biochem Cell Biol. 2009 Aug-Sep;41(8-9):1678-84. doi: 10.1016/j.biocel.2009.02.008. Epub 2009 Feb 23.

PMID:
19433309
16.

Catalytically active Yersinia outer protein P induces cleavage of RIP and caspase-8 at the level of the DISC independently of death receptors in dendritic cells.

Gröbner S, Adkins I, Schulz S, Richter K, Borgmann S, Wesselborg S, Ruckdeschel K, Micheau O, Autenrieth IB.

Apoptosis. 2007 Oct;12(10):1813-25.

PMID:
17624595
17.

Involvement of c-FLIP and survivin down-regulation in flexible heteroarotinoid-induced apoptosis and enhancement of TRAIL-initiated apoptosis in lung cancer cells.

Lin Y, Liu X, Yue P, Benbrook DM, Berlin KD, Khuri FR, Sun SY.

Mol Cancer Ther. 2008 Nov;7(11):3556-65. doi: 10.1158/1535-7163.MCT-08-0648.

18.

RIP-in CD95-induced cell death: The control of alternative death receptors pathways by cIAPs.

Geserick P, Hupe M, Moulin M, Leverkus M.

Cell Cycle. 2010 Jul 15;9(14):2689-91. No abstract available.

PMID:
20581447
19.

Troglitazone-mediated sensitization to TRAIL-induced apoptosis is regulated by proteasome-dependent degradation of FLIP and ERK1/2-dependent phosphorylation of BAD.

Grund K, Ahmadi R, Jung F, Funke V, Gdynia G, Benner A, Sykora J, Walczak H, Joos S, Felsberg J, Reifenberger G, Wiestler OD, Herold-Mende C, Roth W.

Cancer Biol Ther. 2008 Dec;7(12):1982-90.

PMID:
19158480
20.

Calmodulin binding to cellular FLICE-like inhibitory protein modulates Fas-induced signalling.

Pawar PS, Micoli KJ, Ding H, Cook WJ, Kappes JC, Chen Y, McDonald JM.

Biochem J. 2008 Jun 15;412(3):459-68. doi: 10.1042/BJ20071507.

PMID:
18257744
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