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Results: 1 to 20 of 141

1.

Notch inhibition by the ligand DELTA-LIKE 3 defines the mechanism of abnormal vertebral segmentation in spondylocostal dysostosis.

Chapman G, Sparrow DB, Kremmer E, Dunwoodie SL.

Hum Mol Genet. 2011 Mar 1;20(5):905-16. doi: 10.1093/hmg/ddq529. Epub 2010 Dec 7.

PMID:
21147753
[PubMed - indexed for MEDLINE]
Free Article
2.

Role of Delta-like-3 in mammalian somitogenesis and vertebral column formation.

Chapman G, Dunwoodie SL.

Adv Exp Med Biol. 2008;638:95-112. Review.

PMID:
21038772
[PubMed - indexed for MEDLINE]
3.

Dll3 and Notch1 genetic interactions model axial segmental and craniofacial malformations of human birth defects.

Loomes KM, Stevens SA, O'Brien ML, Gonzalez DM, Ryan MJ, Segalov M, Dormans NJ, Mimoto MS, Gibson JD, Sewell W, Schaffer AA, Nah HD, Rappaport EF, Pratt SC, Dunwoodie SL, Kusumi K.

Dev Dyn. 2007 Oct;236(10):2943-51. Erratum in: Dev Dyn. 2008 Jun;237(6):1754.

PMID:
17849441
[PubMed - indexed for MEDLINE]
Free Article
4.

A cell autonomous role for the Notch ligand Delta-like 3 in αβ T-cell development.

Hoyne GF, Chapman G, Sontani Y, Pursglove SE, Dunwoodie SL.

Immunol Cell Biol. 2011 Aug;89(6):696-705. doi: 10.1038/icb.2010.154. Epub 2010 Dec 14.

PMID:
21151194
[PubMed - indexed for MEDLINE]
5.

The divergent DSL ligand Dll3 does not activate Notch signaling but cell autonomously attenuates signaling induced by other DSL ligands.

Ladi E, Nichols JT, Ge W, Miyamoto A, Yao C, Yang LT, Boulter J, Sun YE, Kintner C, Weinmaster G.

J Cell Biol. 2005 Sep 12;170(6):983-92. Epub 2005 Sep 6.

PMID:
16144902
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

The EGF-like proteins DLK1 and DLK2 function as inhibitory non-canonical ligands of NOTCH1 receptor that modulate each other's activities.

Sánchez-Solana B, Nueda ML, Ruvira MD, Ruiz-Hidalgo MJ, Monsalve EM, Rivero S, García-Ramírez JJ, Díaz-Guerra MJ, Baladrón V, Laborda J.

Biochim Biophys Acta. 2011 Jun;1813(6):1153-64. doi: 10.1016/j.bbamcr.2011.03.004. Epub 2011 Mar 15.

PMID:
21419176
[PubMed - indexed for MEDLINE]
Free Article
7.

Novel mutations in DLL3, a somitogenesis gene encoding a ligand for the Notch signalling pathway, cause a consistent pattern of abnormal vertebral segmentation in spondylocostal dysostosis.

Turnpenny PD, Whittock N, Duncan J, Dunwoodie S, Kusumi K, Ellard S.

J Med Genet. 2003 May;40(5):333-9.

PMID:
12746394
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo.

Geffers I, Serth K, Chapman G, Jaekel R, Schuster-Gossler K, Cordes R, Sparrow DB, Kremmer E, Dunwoodie SL, Klein T, Gossler A.

J Cell Biol. 2007 Jul 30;178(3):465-76.

PMID:
17664336
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

The intracellular region of Notch ligands Dll1 and Dll3 regulates their trafficking and signaling activity.

Heuss SF, Ndiaye-Lobry D, Six EM, Israël A, Logeat F.

Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11212-7. doi: 10.1073/pnas.0800695105. Epub 2008 Aug 1.

PMID:
18676613
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Diverse requirements for Notch signalling in mammals.

Sparrow DB, Clements M, Withington SL, Scott AN, Novotny J, Sillence D, Kusumi K, Beddington RS, Dunwoodie SL.

Int J Dev Biol. 2002;46(4):365-74.

PMID:
12141422
[PubMed - indexed for MEDLINE]
Free Article
11.

Axial skeletal defects caused by mutation in the spondylocostal dysplasia/pudgy gene Dll3 are associated with disruption of the segmentation clock within the presomitic mesoderm.

Dunwoodie SL, Clements M, Sparrow DB, Sa X, Conlon RA, Beddington RS.

Development. 2002 Apr;129(7):1795-806.

PMID:
11923214
[PubMed - indexed for MEDLINE]
Free Article
12.

Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system.

Kusumi K, Dunwoodie SL, Krumlauf R.

Mech Dev. 2001 Jan;100(1):141-4.

PMID:
11118901
[PubMed - indexed for MEDLINE]
Free Article
13.

Dll3 pudgy mutation differentially disrupts dynamic expression of somite genes.

Kusumi K, Mimoto MS, Covello KL, Beddington RS, Krumlauf R, Dunwoodie SL.

Genesis. 2004 Jun;39(2):115-21.

PMID:
15170697
[PubMed - indexed for MEDLINE]
14.

Notch signaling in human development and disease.

Penton AL, Leonard LD, Spinner NB.

Semin Cell Dev Biol. 2012 Jun;23(4):450-7. doi: 10.1016/j.semcdb.2012.01.010. Epub 2012 Jan 28. Review.

PMID:
22306179
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Cyclical expression of the Notch/Wnt regulator Nrarp requires modulation by Dll3 in somitogenesis.

Sewell W, Sparrow DB, Smith AJ, Gonzalez DM, Rappaport EF, Dunwoodie SL, Kusumi K.

Dev Biol. 2009 May 15;329(2):400-9. doi: 10.1016/j.ydbio.2009.02.023. Epub 2009 Mar 3.

PMID:
19268448
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Notch-Hes1 pathway contributes to the cochlear prosensory formation potentially through the transcriptional down-regulation of p27Kip1.

Murata J, Ohtsuka T, Tokunaga A, Nishiike S, Inohara H, Okano H, Kageyama R.

J Neurosci Res. 2009 Dec;87(16):3521-34. doi: 10.1002/jnr.22169.

PMID:
19598246
[PubMed - indexed for MEDLINE]
17.

Disruption of the somitic molecular clock causes abnormal vertebral segmentation.

Sparrow DB, Chapman G, Turnpenny PD, Dunwoodie SL.

Birth Defects Res C Embryo Today. 2007 Jun;81(2):93-110. Review.

PMID:
17600782
[PubMed - indexed for MEDLINE]
18.

The role of presenilin 1 during somite segmentation.

Koizumi K, Nakajima M, Yuasa S, Saga Y, Sakai T, Kuriyama T, Shirasawa T, Koseki H.

Development. 2001 Apr;128(8):1391-402.

PMID:
11262239
[PubMed - indexed for MEDLINE]
Free Article
19.

The Nrarp gene encodes an ankyrin-repeat protein that is transcriptionally regulated by the notch signaling pathway.

Krebs LT, Deftos ML, Bevan MJ, Gridley T.

Dev Biol. 2001 Oct 1;238(1):110-9.

PMID:
11783997
[PubMed - indexed for MEDLINE]
Free Article
20.

Interaction between Notch signalling and Lunatic fringe during somite boundary formation in the mouse.

Barrantes IB, Elia AJ, Wünsch K, Hrabe de Angelis MH, Mak TW, Rossant J, Conlon RA, Gossler A, de la Pompa JL.

Curr Biol. 1999 May 6;9(9):470-80.

PMID:
10330372
[PubMed - indexed for MEDLINE]
Free Article
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