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Items: 1 to 20 of 138

1.

Structure of the HIV-1 full-length capsid protein in a conformationally trapped unassembled state induced by small-molecule binding.

Du S, Betts L, Yang R, Shi H, Concel J, Ahn J, Aiken C, Zhang P, Yeh JI.

J Mol Biol. 2011 Feb 25;406(3):371-86. doi: 10.1016/j.jmb.2010.11.027. Epub 2010 Dec 10.

2.

Cryo-electron microscopy of tubular arrays of HIV-1 Gag resolves structures essential for immature virus assembly.

Bharat TA, Castillo Menendez LR, Hagen WJ, Lux V, Igonet S, Schorb M, Schur FK, Kräusslich HG, Briggs JA.

Proc Natl Acad Sci U S A. 2014 Jun 3;111(22):8233-8. doi: 10.1073/pnas.1401455111. Epub 2014 May 19.

3.

Residues in the HIV-1 capsid assembly inhibitor binding site are essential for maintaining the assembly-competent quaternary structure of the capsid protein.

Bartonova V, Igonet S, Sticht J, Glass B, Habermann A, Vaney MC, Sehr P, Lewis J, Rey FA, Kraüsslich HG.

J Biol Chem. 2008 Nov 14;283(46):32024-33. doi: 10.1074/jbc.M804230200. Epub 2008 Sep 4.

5.

A temporospatial map that defines specific steps at which critical surfaces in the Gag MA and CA domains act during immature HIV-1 capsid assembly in cells.

Robinson BA, Reed JC, Geary CD, Swain JV, Lingappa JR.

J Virol. 2014 May;88(10):5718-41. doi: 10.1128/JVI.03609-13. Epub 2014 Mar 12.

6.

Structure of the antiviral assembly inhibitor CAP-1 complex with the HIV-1 CA protein.

Kelly BN, Kyere S, Kinde I, Tang C, Howard BR, Robinson H, Sundquist WI, Summers MF, Hill CP.

J Mol Biol. 2007 Oct 19;373(2):355-66. Epub 2007 Aug 15.

7.

The HIV-1 capsid protein C-terminal domain in complex with a virus assembly inhibitor.

Ternois F, Sticht J, Duquerroy S, Kräusslich HG, Rey FA.

Nat Struct Mol Biol. 2005 Aug;12(8):678-82. Epub 2005 Jul 24.

PMID:
16041386
8.

Structural and functional insights into the HIV-1 maturation inhibitor binding pocket.

Waki K, Durell SR, Soheilian F, Nagashima K, Butler SL, Freed EO.

PLoS Pathog. 2012;8(11):e1002997. doi: 10.1371/journal.ppat.1002997. Epub 2012 Nov 8.

9.

A conformational transition observed in single HIV-1 Gag molecules during in vitro assembly of virus-like particles.

Munro JB, Nath A, Färber M, Datta SA, Rein A, Rhoades E, Mothes W.

J Virol. 2014 Mar;88(6):3577-85. doi: 10.1128/JVI.03353-13. Epub 2014 Jan 8.

10.

Crystal structure of an antiviral ankyrin targeting the HIV-1 capsid and molecular modeling of the ankyrin-capsid complex.

Praditwongwan W, Chuankhayan P, Saoin S, Wisitponchai T, Lee VS, Nangola S, Hong SS, Minard P, Boulanger P, Chen CJ, Tayapiwatana C.

J Comput Aided Mol Des. 2014 Aug;28(8):869-84. doi: 10.1007/s10822-014-9772-9. Epub 2014 Jul 5.

PMID:
24997121
11.

Site-specific structural variations accompanying tubular assembly of the HIV-1 capsid protein.

Bayro MJ, Chen B, Yau WM, Tycko R.

J Mol Biol. 2014 Mar 6;426(5):1109-27. doi: 10.1016/j.jmb.2013.12.021. Epub 2013 Dec 24.

12.

Structure of the carboxyl-terminal dimerization domain of the HIV-1 capsid protein.

Gamble TR, Yoo S, Vajdos FF, von Schwedler UK, Worthylake DK, Wang H, McCutcheon JP, Sundquist WI, Hill CP.

Science. 1997 Oct 31;278(5339):849-53.

13.

Novel inhibitor binding site discovery on HIV-1 capsid N-terminal domain by NMR and X-ray crystallography.

Goudreau N, Lemke CT, Faucher AM, Grand-Maître C, Goulet S, Lacoste JE, Rancourt J, Malenfant E, Mercier JF, Titolo S, Mason SW.

ACS Chem Biol. 2013 May 17;8(5):1074-82. doi: 10.1021/cb400075f. Epub 2013 Mar 25.

PMID:
23496828
14.

Distinct effects of two HIV-1 capsid assembly inhibitor families that bind the same site within the N-terminal domain of the viral CA protein.

Lemke CT, Titolo S, von Schwedler U, Goudreau N, Mercier JF, Wardrop E, Faucher AM, Coulombe R, Banik SS, Fader L, Gagnon A, Kawai SH, Rancourt J, Tremblay M, Yoakim C, Simoneau B, Archambault J, Sundquist WI, Mason SW.

J Virol. 2012 Jun;86(12):6643-55. doi: 10.1128/JVI.00493-12. Epub 2012 Apr 11.

15.

Structure of full-length HIV-1 CA: a model for the mature capsid lattice.

Ganser-Pornillos BK, Cheng A, Yeager M.

Cell. 2007 Oct 5;131(1):70-9.

16.

Motions on the millisecond time scale and multiple conformations of HIV-1 capsid protein: implications for structural polymorphism of CA assemblies.

Byeon IJ, Hou G, Han Y, Suiter CL, Ahn J, Jung J, Byeon CH, Gronenborn AM, Polenova T.

J Am Chem Soc. 2012 Apr 11;134(14):6455-66. doi: 10.1021/ja300937v. Epub 2012 Apr 2.

17.

1H, 15N and 13C assignments of the dimeric C-terminal domain of HIV-1 capsid protein.

Jung J, Byeon IJ, Ahn J, Concel J, Gronenborn AM.

Biomol NMR Assign. 2010 Apr;4(1):21-3. doi: 10.1007/s12104-009-9198-9. Epub 2009 Nov 18.

18.

The structural biology of HIV assembly.

Ganser-Pornillos BK, Yeager M, Sundquist WI.

Curr Opin Struct Biol. 2008 Apr;18(2):203-17. doi: 10.1016/j.sbi.2008.02.001. Epub 2008 Apr 9. Review.

19.

Structure of a monomeric mutant of the HIV-1 capsid protein.

Shin R, Tzou YM, Krishna NR.

Biochemistry. 2011 Nov 8;50(44):9457-67. doi: 10.1021/bi2011493. Epub 2011 Oct 13. Erratum in: Biochemistry. 2011 Nov 8;50(44):9467.

20.

Structure and dynamics of full-length HIV-1 capsid protein in solution.

Deshmukh L, Schwieters CD, Grishaev A, Ghirlando R, Baber JL, Clore GM.

J Am Chem Soc. 2013 Oct 30;135(43):16133-47. doi: 10.1021/ja406246z. Epub 2013 Oct 17.

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