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Photodynamic therapy with a cationic functionalized fullerene rescues mice from fatal wound infections.

Lu Z, Dai T, Huang L, Kurup DB, Tegos GP, Jahnke A, Wharton T, Hamblin MR.

Nanomedicine (Lond). 2010 Dec;5(10):1525-33. doi: 10.2217/nnm.10.98.


Optical monitoring and treatment of potentially lethal wound infections in vivo.

Hamblin MR, Zahra T, Contag CH, McManus AT, Hasan T.

J Infect Dis. 2003 Jun 1;187(11):1717-25. Epub 2003 May 15.


Topical photodynamic treatment with poly-L-lysine-chlorin p6 conjugate improves wound healing by reducing hyperinflammatory response in Pseudomonas aeruginosa-infected wounds of mice.

Sahu K, Sharma M, Bansal H, Dube A, Gupta PK.

Lasers Med Sci. 2013 Feb;28(2):465-71. doi: 10.1007/s10103-012-1083-6. Epub 2012 Mar 28.


Antimicrobial photodynamic therapy with fulleropyrrolidine: photoinactivation mechanism of Staphylococcus aureus, in vitro and in vivo studies.

Grinholc M, Nakonieczna J, Fila G, Taraszkiewicz A, Kawiak A, Szewczyk G, Sarna T, Lilge L, Bielawski KP.

Appl Microbiol Biotechnol. 2015 May;99(9):4031-43. doi: 10.1007/s00253-015-6539-8. Epub 2015 Mar 29.


Potentiation of antimicrobial photodynamic inactivation mediated by a cationic fullerene by added iodide: in vitro and in vivo studies.

Zhang Y, Dai T, Wang M, Vecchio D, Chiang LY, Hamblin MR.

Nanomedicine (Lond). 2015 Mar;10(4):603-14. doi: 10.2217/nnm.14.131.


Intraperitoneal photodynamic therapy mediated by a fullerene in a mouse model of abdominal dissemination of colon adenocarcinoma.

Mroz P, Xia Y, Asanuma D, Konopko A, Zhiyentayev T, Huang YY, Sharma SK, Dai T, Khan UJ, Wharton T, Hamblin MR.

Nanomedicine. 2011 Dec;7(6):965-74. doi: 10.1016/j.nano.2011.04.007. Epub 2011 May 19.


A clinical study of photodynamic therapy for chronic skin ulcers in lower limbs infected with Pseudomonas aeruginosa.

Lei X, Liu B, Huang Z, Wu J.

Arch Dermatol Res. 2015 Jan;307(1):49-55. doi: 10.1007/s00403-014-1520-4. Epub 2014 Nov 20.


Photodynamic therapy with fullerenes in vivo: reality or a dream?

Sharma SK, Chiang LY, Hamblin MR.

Nanomedicine (Lond). 2011 Dec;6(10):1813-25. doi: 10.2217/nnm.11.144.


Rapid control of wound infections by targeted photodynamic therapy monitored by in vivo bioluminescence imaging.

Hamblin MR, O'Donnell DA, Murthy N, Contag CH, Hasan T.

Photochem Photobiol. 2002 Jan;75(1):51-7.


Study of photodynamic therapy in the control of isolated microorganisms from infected wounds--an in vitro study.

Pereira de Lima Carvalho D, Guerra Pinto J, Di Paula Costa Sorge C, Rodrigues Benedito FR, Khouri S, Ferreira Strixino J.

Lasers Med Sci. 2014 Jan;29(1):113-20. doi: 10.1007/s10103-013-1283-8. Epub 2013 Mar 1.


Blue light rescues mice from potentially fatal Pseudomonas aeruginosa burn infection: efficacy, safety, and mechanism of action.

Dai T, Gupta A, Huang YY, Yin R, Murray CK, Vrahas MS, Sherwood ME, Tegos GP, Hamblin MR.

Antimicrob Agents Chemother. 2013 Mar;57(3):1238-45. doi: 10.1128/AAC.01652-12. Epub 2012 Dec 21.


Monitoring photodynamic therapy of localized infections by bioluminescence imaging of genetically engineered bacteria.

Demidova TN, Gad F, Zahra T, Francis KP, Hamblin MR.

J Photochem Photobiol B. 2005 Oct 3;81(1):15-25.


Antimicrobial photodynamic therapy on drug-resistant Pseudomonas aeruginosa-induced infection. An in vivo study.

Hashimoto MC, Prates RA, Kato IT, Núñez SC, Courrol LC, Ribeiro MS.

Photochem Photobiol. 2012 May-Jun;88(3):590-5. doi: 10.1111/j.1751-1097.2012.01137.x. Epub 2012 Mar 30.


A tumoral acidic pH-responsive drug delivery system based on a novel photosensitizer (fullerene) for in vitro and in vivo chemo-photodynamic therapy.

Shi J, Liu Y, Wang L, Gao J, Zhang J, Yu X, Ma R, Liu R, Zhang Z.

Acta Biomater. 2014 Mar;10(3):1280-91. doi: 10.1016/j.actbio.2013.10.037. Epub 2013 Nov 6.


Use of chitosan bandage to prevent fatal infections developing from highly contaminated wounds in mice.

Burkatovskaya M, Tegos GP, Swietlik E, Demidova TN, P Castano A, Hamblin MR.

Biomaterials. 2006 Aug;27(22):4157-64. Epub 2006 Apr 17.


Functionalized fullerenes in photodynamic therapy.

Huang YY, Sharma SK, Yin R, Agrawal T, Chiang LY, Hamblin MR.

J Biomed Nanotechnol. 2014 Sep;10(9):1918-36. Review.


Cationic fullerenes are effective and selective antimicrobial photosensitizers.

Tegos GP, Demidova TN, Arcila-Lopez D, Lee H, Wharton T, Gali H, Hamblin MR.

Chem Biol. 2005 Oct;12(10):1127-35.


Drug discovery of antimicrobial photosensitizers using animal models.

Sharma SK, Dai T, Kharkwal GB, Huang YY, Huang L, De Arce VJ, Tegos GP, Hamblin MR.

Curr Pharm Des. 2011;17(13):1303-19. Review.


Targeted photodynamic therapy of established soft-tissue infections in mice.

Gad F, Zahra T, Francis KP, Hasan T, Hamblin MR.

Photochem Photobiol Sci. 2004 May;3(5):451-8. Epub 2004 Feb 11.

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