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Results: 1 to 20 of 102

1.

Antiplatelet activity of valproic acid contributes to decreased soluble CD40 ligand production in HIV type 1-infected individuals.

Davidson DC, Hirschman MP, Spinelli SL, Morrell CN, Schifitto G, Phipps RP, Maggirwar SB.

J Immunol. 2011 Jan 1;186(1):584-91. doi: 10.4049/jimmunol.1001911. Epub 2010 Nov 29.

PMID:
21115729
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Valproic acid inhibits the release of soluble CD40L induced by non-nucleoside reverse transcriptase inhibitors in human immunodeficiency virus infected individuals.

Davidson DC, Schifitto G, Maggirwar SB.

PLoS One. 2013;8(3):e59950. doi: 10.1371/journal.pone.0059950. Epub 2013 Mar 28.

PMID:
23555843
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Excess soluble CD40L contributes to blood brain barrier permeability in vivo: implications for HIV-associated neurocognitive disorders.

Davidson DC, Hirschman MP, Sun A, Singh MV, Kasischke K, Maggirwar SB.

PLoS One. 2012;7(12):e51793. doi: 10.1371/journal.pone.0051793. Epub 2012 Dec 12.

PMID:
23251626
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Targeting platelet-derived soluble CD40 ligand: a new treatment strategy for HIV-associated neuroinflammation?

Davidson DC, Jackson JW, Maggirwar SB.

J Neuroinflammation. 2013 Dec 1;10:144. doi: 10.1186/1742-2094-10-144. Review.

PMID:
24289660
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Release of soluble CD40L from platelets is regulated by glycoprotein IIb/IIIa and actin polymerization.

Furman MI, Krueger LA, Linden MD, Barnard MR, Frelinger AL 3rd, Michelson AD.

J Am Coll Cardiol. 2004 Jun 16;43(12):2319-25.

PMID:
15193700
[PubMed - indexed for MEDLINE]
Free Article
6.

Soluble CD40 ligand stimulates CD40-dependent activation of the β2 integrin Mac-1 and protein kinase C zeda (PKCζ) in neutrophils: implications for neutrophil-platelet interactions and neutrophil oxidative burst.

Jin R, Yu S, Song Z, Zhu X, Wang C, Yan J, Wu F, Nanda A, Granger DN, Li G.

PLoS One. 2013 Jun 6;8(6):e64631. doi: 10.1371/journal.pone.0064631. Print 2013.

PMID:
23785403
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Functional synergy between CD40 ligand and HIV-1 Tat contributes to inflammation: implications in HIV type 1 dementia.

Sui Z, Sniderhan LF, Schifitto G, Phipps RP, Gelbard HA, Dewhurst S, Maggirwar SB.

J Immunol. 2007 Mar 1;178(5):3226-36.

PMID:
17312171
[PubMed - indexed for MEDLINE]
Free Article
8.

Elevated release of sCD40L from platelets of diabetic patients by thrombin, glucose and advanced glycation end products.

Varo N, Libby P, Nuzzo R, Italiano J, Doria A, Schönbeck U.

Diab Vasc Dis Res. 2005 May;2(2):81-7.

PMID:
16308911
[PubMed - indexed for MEDLINE]
Free Article
9.

Thromboxane A(2) promotes soluble CD40 ligand release from human platelets.

Enomoto Y, Adachi S, Matsushima-Nishiwaki R, Doi T, Niwa M, Akamatsu S, Tokuda H, Ogura S, Yoshimura S, Iwama T, Kozawa O.

Atherosclerosis. 2010 Apr;209(2):415-21. doi: 10.1016/j.atherosclerosis.2009.10.024. Epub 2009 Oct 29.

PMID:
19932480
[PubMed - indexed for MEDLINE]
10.

Levels of soluble CD40 ligand (CD154) in serum are increased in human immunodeficiency virus type 1-infected patients and correlate with CD4(+) T-cell counts.

Sipsas NV, Sfikakis PP, Kontos A, Kordossis T.

Clin Diagn Lab Immunol. 2002 May;9(3):558-61.

PMID:
11986259
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

HIV-1 Tat-induced platelet activation and release of CD154 contribute to HIV-1-associated autoimmune thrombocytopenia.

Wang J, Zhang W, Nardi MA, Li Z.

J Thromb Haemost. 2011 Mar;9(3):562-73. doi: 10.1111/j.1538-7836.2010.04168.x.

PMID:
21143381
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Effects of valproic acid derivatives on inositol trisphosphate depletion, teratogenicity, glycogen synthase kinase-3beta inhibition, and viral replication: a screening approach for new bipolar disorder drugs derived from the valproic acid core structure.

Eickholt BJ, Towers GJ, Ryves WJ, Eikel D, Adley K, Ylinen LM, Chadborn NH, Harwood AJ, Nau H, Williams RS.

Mol Pharmacol. 2005 May;67(5):1426-33. Epub 2005 Feb 1.

PMID:
15687223
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Biologically active CD40 ligand is elevated in sickle cell anemia: potential role for platelet-mediated inflammation.

Lee SP, Ataga KI, Orringer EP, Phillips DR, Parise LV.

Arterioscler Thromb Vasc Biol. 2006 Jul;26(7):1626-31. Epub 2006 Apr 6.

PMID:
16601237
[PubMed - indexed for MEDLINE]
Free Article
14.

Glycogen synthase kinase 3 beta (GSK-3 beta) as a therapeutic target in neuroAIDS.

Dewhurst S, Maggirwar SB, Schifitto G, Gendelman HE, Gelbard HA.

J Neuroimmune Pharmacol. 2007 Mar;2(1):93-6. Epub 2006 Dec 16. Review.

PMID:
18040831
[PubMed - indexed for MEDLINE]
15.

Activated platelets are the source of elevated levels of soluble CD40 ligand in the circulation of inflammatory bowel disease patients.

Danese S, Katz JA, Saibeni S, Papa A, Gasbarrini A, Vecchi M, Fiocchi C.

Gut. 2003 Oct;52(10):1435-41.

PMID:
12970136
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Soluble CD40 ligand induces beta3 integrin tyrosine phosphorylation and triggers platelet activation by outside-in signaling.

Prasad KS, Andre P, He M, Bao M, Manganello J, Phillips DR.

Proc Natl Acad Sci U S A. 2003 Oct 14;100(21):12367-71. Epub 2003 Sep 30.

PMID:
14519852
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Analysis of serum soluble CD40 ligand (sCD40L) in the patients undergoing allogeneic stem cell transplantation: platelet is a major source of serum sCD40L.

Nagasawa M, Zhu Y, Isoda T, Tomizawa D, Itoh S, Kajiwara M, Morio T, Nonoyama S, Shimizu N, Mizutani S.

Eur J Haematol. 2005 Jan;74(1):54-60.

PMID:
15613107
[PubMed - indexed for MEDLINE]
18.

Interaction with damaged vessel wall in vivo in humans induces platelets to express CD40L resulting in endothelial activation with no effect of aspirin intake.

Giannini S, Falcinelli E, Bury L, Guglielmini G, Rossi R, Momi S, Gresele P.

Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2072-9. doi: 10.1152/ajpheart.00467.2010. Epub 2011 Mar 4.

PMID:
21378140
[PubMed - indexed for MEDLINE]
Free Article
19.

Chronic immune activation in HIV-1 infection contributes to reduced interferon alpha production via enhanced CD40:CD40 ligand interaction.

Donhauser N, Pritschet K, Helm M, Harrer T, Schuster P, Ries M, Bischof G, Vollmer J, Smola S, Schmidt B; German Competence Network HIV/AIDS.

PLoS One. 2012;7(3):e33925. doi: 10.1371/journal.pone.0033925. Epub 2012 Mar 21.

PMID:
22470494
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Preliminary evidence for a matrix metalloproteinase-2 (MMP-2)-dependent shedding of soluble CD40 ligand (sCD40L) from activated platelets.

Reinboldt S, Wenzel F, Rauch BH, Hohlfeld T, Grandoch M, Fischer JW, Weber AA.

Platelets. 2009 Sep;20(6):441-4.

PMID:
19811225
[PubMed - indexed for MEDLINE]

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