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Results: 1 to 20 of 94

1.

Hypericins and thioredoxin reductase: Biochemical and docking studies disclose the molecular basis for effective inhibition by naphthodianthrones.

Sorrentino F, Karioti A, Gratteri P, Rigobello MP, Scutari G, Messori L, Bindoli A, Chioccioli M, Gabbiani C, Bergonzi MC, Bilia AR.

Bioorg Med Chem. 2011 Jan 1;19(1):631-41. doi: 10.1016/j.bmc.2010.10.045. Epub 2010 Oct 25.

PMID:
21106380
[PubMed - indexed for MEDLINE]
2.

Inhibition of mammalian thioredoxin reductase by black tea and its constituents: implications for anticancer actions.

Du Y, Wu Y, Cao X, Cui W, Zhang H, Tian W, Ji M, Holmgren A, Zhong L.

Biochimie. 2009 Mar;91(3):434-44. doi: 10.1016/j.biochi.2008.11.005. Epub 2008 Nov 27.

PMID:
19059456
[PubMed - indexed for MEDLINE]
3.

Human selenium-dependent thioredoxin reductase from HeLa cells: properties of forms with differing heparin affinities.

Gorlatov SN, Stadtman TC.

Arch Biochem Biophys. 1999 Sep 1;369(1):133-42.

PMID:
10462449
[PubMed - indexed for MEDLINE]
4.

Thioredoxin reductase is irreversibly modified by curcumin: a novel molecular mechanism for its anticancer activity.

Fang J, Lu J, Holmgren A.

J Biol Chem. 2005 Jul 1;280(26):25284-90. Epub 2005 May 6.

PMID:
15879598
[PubMed - indexed for MEDLINE]
Free Article
5.

Molecular cloning and characterization of a mitochondrial selenocysteine-containing thioredoxin reductase from rat liver.

Lee SR, Kim JR, Kwon KS, Yoon HW, Levine RL, Ginsburg A, Rhee SG.

J Biol Chem. 1999 Feb 19;274(8):4722-34.

PMID:
9988709
[PubMed - indexed for MEDLINE]
Free Article
6.

Thioredoxin reductase from the malaria mosquito Anopheles gambiae.

Bauer H, Gromer S, Urbani A, Schnölzer M, Schirmer RH, Müller HM.

Eur J Biochem. 2003 Nov;270(21):4272-81.

PMID:
14622292
[PubMed - indexed for MEDLINE]
Free Article
7.

Sublethal concentrations of diverse gold compounds inhibit mammalian cytosolic thioredoxin reductase (TrxR1).

Omata Y, Folan M, Shaw M, Messer RL, Lockwood PE, Hobbs D, Bouillaguet S, Sano H, Lewis JB, Wataha JC.

Toxicol In Vitro. 2006 Sep;20(6):882-90. Epub 2006 Feb 28.

PMID:
16510263
[PubMed - indexed for MEDLINE]
8.

Inhibition of both thioredoxin reductase and glutathione reductase may contribute to the anticancer mechanism of TH-302.

Li S, Zhang J, Li J, Chen D, Matteucci M, Curd J, Duan JX.

Biol Trace Elem Res. 2010 Sep;136(3):294-301. doi: 10.1007/s12011-009-8544-1. Epub 2009 Oct 17.

PMID:
19838642
[PubMed - indexed for MEDLINE]
9.

Mitochondrial thioredoxin reductase in bovine adrenal cortex its purification, properties, nucleotide/amino acid sequences, and identification of selenocysteine.

Watabe S, Makino Y, Ogawa K, Hiroi T, Yamamoto Y, Takahashi SY.

Eur J Biochem. 1999 Aug;264(1):74-84.

PMID:
10447675
[PubMed - indexed for MEDLINE]
Free Article
10.

Mitochondrial thioredoxin reductase purification, inhibitor studies, and role in cell signaling.

Rigobello MP, Bindoli A.

Methods Enzymol. 2010;474:109-22. doi: 10.1016/S0076-6879(10)74007-6. Epub 2010 Jun 20.

PMID:
20609907
[PubMed - indexed for MEDLINE]
11.

Inhibitory effect of green tea extract and (-)-epigallocatechin-3-gallate on mammalian thioredoxin reductase and HeLa cell viability.

Wang Y, Zhang H, Holmgren A, Tian W, Zhong L.

Oncol Rep. 2008 Dec;20(6):1479-87.

PMID:
19020731
[PubMed - indexed for MEDLINE]
12.

Crystal structure of Escherichia coli thioredoxin reductase refined at 2 A resolution. Implications for a large conformational change during catalysis.

Waksman G, Krishna TS, Williams CH Jr, Kuriyan J.

J Mol Biol. 1994 Feb 25;236(3):800-16.

PMID:
8114095
[PubMed - indexed for MEDLINE]
13.

Expression, purification and molecular structure modeling of thioredoxin (Trx) and thioredoxin reductase (TrxR) from Acidithiobacillus ferrooxidans.

Wang Y, Zhang X, Liu Q, Ai C, Mo H, Zeng J.

Curr Microbiol. 2009 Jul;59(1):35-41. doi: 10.1007/s00284-009-9390-2. Epub 2009 Mar 25.

PMID:
19319598
[PubMed - indexed for MEDLINE]
14.

Substrate and inhibitor specificities differ between human cytosolic and mitochondrial thioredoxin reductases: Implications for development of specific inhibitors.

Rackham O, Shearwood AM, Thyer R, McNamara E, Davies SM, Callus BA, Miranda-Vizuete A, Berners-Price SJ, Cheng Q, Arnér ES, Filipovska A.

Free Radic Biol Med. 2011 Mar 15;50(6):689-99. doi: 10.1016/j.freeradbiomed.2010.12.015. Epub 2010 Dec 21.

PMID:
21172426
[PubMed - indexed for MEDLINE]
15.

Three-dimensional structure of a mammalian thioredoxin reductase: implications for mechanism and evolution of a selenocysteine-dependent enzyme.

Sandalova T, Zhong L, Lindqvist Y, Holmgren A, Schneider G.

Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9533-8. Epub 2001 Jul 31.

PMID:
11481439
[PubMed - indexed for MEDLINE]
Free PMC Article
16.
17.

Rapid induction of cell death by selenium-compromised thioredoxin reductase 1 but not by the fully active enzyme containing selenocysteine.

Anestål K, Arnér ES.

J Biol Chem. 2003 May 2;278(18):15966-72. Epub 2003 Feb 6.

PMID:
12574159
[PubMed - indexed for MEDLINE]
Free Article
18.

Inhibition of thioredoxin reductase by lanthanum chloride.

Citta A, Folda A, Scutari G, Cesaro L, Bindoli A, Rigobello MP.

J Inorg Biochem. 2012 Dec;117:18-24. doi: 10.1016/j.jinorgbio.2012.08.014. Epub 2012 Aug 31.

PMID:
23078771
[PubMed - indexed for MEDLINE]
19.

Inhibition of Mammalian thioredoxin reductase by some flavonoids: implications for myricetin and quercetin anticancer activity.

Lu J, Papp LV, Fang J, Rodriguez-Nieto S, Zhivotovsky B, Holmgren A.

Cancer Res. 2006 Apr 15;66(8):4410-8.

PMID:
16618767
[PubMed - indexed for MEDLINE]
Free Article
20.

Photocytotoxic effect of pseudohypericin versus hypericin.

Vandenbogaerde AL, Kamuhabwa A, Delaey E, Himpens BE, Merlevede WJ, de Witte PA.

J Photochem Photobiol B. 1998 Sep;45(2-3):87-94.

PMID:
9868799
[PubMed - indexed for MEDLINE]

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