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Results: 1 to 20 of 110

1.

RhoH regulates subcellular localization of ZAP-70 and Lck in T cell receptor signaling.

Chae HD, Siefring JE, Hildeman DA, Gu Y, Williams DA.

PLoS One. 2010 Nov 12;5(11):e13970. doi: 10.1371/journal.pone.0013970.

PMID:
21103055
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

RhoH GTPase recruits and activates Zap70 required for T cell receptor signaling and thymocyte development.

Gu Y, Chae HD, Siefring JE, Jasti AC, Hildeman DA, Williams DA.

Nat Immunol. 2006 Nov;7(11):1182-90. Epub 2006 Oct 8.

PMID:
17028588
[PubMed - indexed for MEDLINE]
3.

RhoH modulates pre-TCR and TCR signalling by regulating LCK.

Wang H, Zeng X, Fan Z, Lim B.

Cell Signal. 2011 Jan;23(1):249-58. doi: 10.1016/j.cellsig.2010.09.009. Epub 2010 Sep 16.

PMID:
20851766
[PubMed - indexed for MEDLINE]
4.

T-cell receptor signaling is mediated by transient Lck activity, which is inhibited by inorganic mercury.

Ziemba SE, Menard SL, McCabe MJ Jr, Rosenspire AJ.

FASEB J. 2009 Jun;23(6):1663-71. doi: 10.1096/fj.08-117283. Epub 2009 Jan 23.

PMID:
19168706
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Subcellular distribution of Lck during CD4 T-cell maturation in the thymic medulla regulates the T-cell activation threshold.

Stephen TL, Wilson BS, Laufer TM.

Proc Natl Acad Sci U S A. 2012 May 8;109(19):7415-20. doi: 10.1073/pnas.1119272109. Epub 2012 Apr 23.

PMID:
22529380
[PubMed - indexed for MEDLINE]
Free PMC Article
6.
7.

Dexamethasone induces rapid tyrosine-phosphorylation of ZAP-70 in Jurkat cells.

Bartis D, Boldizsár F, Szabó M, Pálinkás L, Németh P, Berki T.

J Steroid Biochem Mol Biol. 2006 Feb;98(2-3):147-54. Epub 2006 Jan 6.

PMID:
16406604
[PubMed - indexed for MEDLINE]
8.

Roles of Lck, Syk and ZAP-70 tyrosine kinases in TCR-mediated phosphorylation of the adapter protein Shc.

Walk SF, March ME, Ravichandran KS.

Eur J Immunol. 1998 Aug;28(8):2265-75.

PMID:
9710204
[PubMed - indexed for MEDLINE]
9.

Docking protein Gab2 is phosphorylated by ZAP-70 and negatively regulates T cell receptor signaling by recruitment of inhibitory molecules.

Yamasaki S, Nishida K, Hibi M, Sakuma M, Shiina R, Takeuchi A, Ohnishi H, Hirano T, Saito T.

J Biol Chem. 2001 Nov 30;276(48):45175-83. Epub 2001 Sep 25.

PMID:
11572860
[PubMed - indexed for MEDLINE]
Free Article
10.

The lck SH3 domain is required for activation of the mitogen-activated protein kinase pathway but not the initiation of T-cell antigen receptor signaling.

Denny MF, Kaufman HC, Chan AC, Straus DB.

J Biol Chem. 1999 Feb 19;274(8):5146-52.

PMID:
9988764
[PubMed - indexed for MEDLINE]
Free Article
11.

Lysosomal degradation of RhoH protein upon antigen receptor activation in T but not B cells.

Schmidt-Mende J, Geering B, Yousefi S, Simon HU.

Eur J Immunol. 2010 Feb;40(2):525-9. doi: 10.1002/eji.200939556.

PMID:
19950172
[PubMed - indexed for MEDLINE]
12.

Genetic evidence of a role for Lck in T-cell receptor function independent or downstream of ZAP-70/Syk protein tyrosine kinases.

Wong J, Straus D, Chan AC.

Mol Cell Biol. 1998 May;18(5):2855-66.

PMID:
9566904
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Differential T-cell antigen receptor signaling mediated by the Src family kinases Lck and Fyn.

Denny MF, Patai B, Straus DB.

Mol Cell Biol. 2000 Feb;20(4):1426-35.

PMID:
10648627
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

RhoH is important for positive thymocyte selection and T-cell receptor signaling.

Dorn T, Kuhn U, Bungartz G, Stiller S, Bauer M, Ellwart J, Peters T, Scharffetter-Kochanek K, Semmrich M, Laschinger M, Holzmann B, Klinkert WE, Straten PT, Køllgaard T, Sixt M, Brakebusch C.

Blood. 2007 Mar 15;109(6):2346-55. Epub 2006 Nov 21.

PMID:
17119112
[PubMed - indexed for MEDLINE]
Free Article
15.

Mutation of tyrosines 492/493 in the kinase domain of ZAP-70 affects multiple T-cell receptor signaling pathways.

Mège D, Di Bartolo V, Germain V, Tuosto L, Michel F, Acuto O.

J Biol Chem. 1996 Dec 20;271(51):32644-52.

PMID:
8955094
[PubMed - indexed for MEDLINE]
Free Article
16.

Lck regulates the tyrosine phosphorylation of the T cell receptor subunits and ZAP-70 in murine thymocytes.

van Oers NS, Killeen N, Weiss A.

J Exp Med. 1996 Mar 1;183(3):1053-62.

PMID:
8642247
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Differential Src family kinase activity requirements for CD3 zeta phosphorylation/ZAP70 recruitment and CD3 epsilon phosphorylation.

Lysechko TL, Ostergaard HL.

J Immunol. 2005 Jun 15;174(12):7807-14.

PMID:
15944285
[PubMed - indexed for MEDLINE]
Free Article
18.
19.

Age-related impairments in TCR/CD3 activation of ZAP-70 are associated with reduced tyrosine phosphorylations of zeta-chains and p59fyn/p56lck in human T cells.

Whisler RL, Chen M, Liu B, Newhouse YG.

Mech Ageing Dev. 1999 Nov 2;111(1):49-66.

PMID:
10576607
[PubMed - indexed for MEDLINE]
20.

Lck-dependent tyrosine phosphorylation of diacylglycerol kinase alpha regulates its membrane association in T cells.

Merino E, Avila-Flores A, Shirai Y, Moraga I, Saito N, Mérida I.

J Immunol. 2008 May 1;180(9):5805-15.

PMID:
18424699
[PubMed - indexed for MEDLINE]
Free Article

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