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Results: 1 to 20 of 176

1.

The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic dinucleotides.

Sauer JD, Sotelo-Troha K, von Moltke J, Monroe KM, Rae CS, Brubaker SW, Hyodo M, Hayakawa Y, Woodward JJ, Portnoy DA, Vance RE.

Infect Immun. 2011 Feb;79(2):688-94. doi: 10.1128/IAI.00999-10. Epub 2010 Nov 22.

PMID:
21098106
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

STING is a direct innate immune sensor of cyclic di-GMP.

Burdette DL, Monroe KM, Sotelo-Troha K, Iwig JS, Eckert B, Hyodo M, Hayakawa Y, Vance RE.

Nature. 2011 Sep 25;478(7370):515-8. doi: 10.1038/nature10429.

PMID:
21947006
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response.

Parvatiyar K, Zhang Z, Teles RM, Ouyang S, Jiang Y, Iyer SS, Zaver SA, Schenk M, Zeng S, Zhong W, Liu ZJ, Modlin RL, Liu YJ, Cheng G.

Nat Immunol. 2012 Dec;13(12):1155-61. doi: 10.1038/ni.2460. Epub 2012 Nov 11.

PMID:
23142775
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

MPYS is required for IFN response factor 3 activation and type I IFN production in the response of cultured phagocytes to bacterial second messengers cyclic-di-AMP and cyclic-di-GMP.

Jin L, Hill KK, Filak H, Mogan J, Knowles H, Zhang B, Perraud AL, Cambier JC, Lenz LL.

J Immunol. 2011 Sep 1;187(5):2595-601. doi: 10.4049/jimmunol.1100088. Epub 2011 Aug 3.

PMID:
21813776
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Cyclic di-AMP is critical for Listeria monocytogenes growth, cell wall homeostasis, and establishment of infection.

Witte CE, Whiteley AT, Burke TP, Sauer JD, Portnoy DA, Woodward JJ.

MBio. 2013 May 28;4(3):e00282-13. doi: 10.1128/mBio.00282-13.

PMID:
23716572
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Novel c-di-GMP recognition modes of the mouse innate immune adaptor protein STING.

Chin KH, Tu ZL, Su YC, Yu YJ, Chen HC, Lo YC, Chen CP, Barber GN, Chuah ML, Liang ZX, Chou SH.

Acta Crystallogr D Biol Crystallogr. 2013 Mar;69(Pt 3):352-66. doi: 10.1107/S0907444912047269. Epub 2013 Feb 16. Erratum in: Acta Crystallogr D Biol Crystallogr. 2013 Jun;69(Pt 6):1191.

PMID:
23519410
[PubMed - indexed for MEDLINE]
7.

STING-dependent recognition of cyclic di-AMP mediates type I interferon responses during Chlamydia trachomatis infection.

Barker JR, Koestler BJ, Carpenter VK, Burdette DL, Waters CM, Vance RE, Valdivia RH.

MBio. 2013 Apr 30;4(3):e00018-13. doi: 10.1128/mBio.00018-13.

PMID:
23631912
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Hyperinduction of host beta interferon by a Listeria monocytogenes strain naturally overexpressing the multidrug efflux pump MdrT.

Schwartz KT, Carleton JD, Quillin SJ, Rollins SD, Portnoy DA, Leber JH.

Infect Immun. 2012 Apr;80(4):1537-45. doi: 10.1128/IAI.06286-11. Epub 2012 Jan 30.

PMID:
22290148
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Innate sensing of bacterial cyclic dinucleotides: more than just STING.

Bowie AG.

Nat Immunol. 2012 Dec;13(12):1137-9. doi: 10.1038/ni.2469. No abstract available.

PMID:
23160208
[PubMed - indexed for MEDLINE]
10.

c-di-AMP secreted by intracellular Listeria monocytogenes activates a host type I interferon response.

Woodward JJ, Iavarone AT, Portnoy DA.

Science. 2010 Jun 25;328(5986):1703-5. doi: 10.1126/science.1189801. Epub 2010 May 27.

PMID:
20508090
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

RIG-I detects triphosphorylated RNA of Listeria monocytogenes during infection in non-immune cells.

Hagmann CA, Herzner AM, Abdullah Z, Zillinger T, Jakobs C, Schuberth C, Coch C, Higgins PG, Wisplinghoff H, Barchet W, Hornung V, Hartmann G, Schlee M.

PLoS One. 2013 Apr 30;8(4):e62872. doi: 10.1371/journal.pone.0062872. Print 2013.

PMID:
23653683
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP.

McWhirter SM, Barbalat R, Monroe KM, Fontana MF, Hyodo M, Joncker NT, Ishii KJ, Akira S, Colonna M, Chen ZJ, Fitzgerald KA, Hayakawa Y, Vance RE.

J Exp Med. 2009 Aug 31;206(9):1899-911. doi: 10.1084/jem.20082874. Epub 2009 Aug 3.

PMID:
19652017
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Crystallization studies of the murine c-di-GMP sensor protein STING.

Su YC, Tu ZL, Yang CY, Chin KH, Chuah ML, Liang ZX, Chou SH.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Aug 1;68(Pt 8):906-10. doi: 10.1107/S1744309112024372. Epub 2012 Jul 31.

PMID:
22869119
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Listeria monocytogenes multidrug resistance transporters and cyclic di-AMP, which contribute to type I interferon induction, play a role in cell wall stress.

Kaplan Zeevi M, Shafir NS, Shaham S, Friedman S, Sigal N, Nir Paz R, Boneca IG, Herskovits AA.

J Bacteriol. 2013 Dec;195(23):5250-61. doi: 10.1128/JB.00794-13. Epub 2013 Sep 20.

PMID:
24056102
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Mice lacking the type I interferon receptor are resistant to Listeria monocytogenes.

Auerbuch V, Brockstedt DG, Meyer-Morse N, O'Riordan M, Portnoy DA.

J Exp Med. 2004 Aug 16;200(4):527-33. Epub 2004 Aug 9.

PMID:
15302899
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STING.

Zhang L, Mo J, Swanson KV, Wen H, Petrucelli A, Gregory SM, Zhang Z, Schneider M, Jiang Y, Fitzgerald KA, Ouyang S, Liu ZJ, Damania B, Shu HB, Duncan JA, Ting JP.

Immunity. 2014 Mar 20;40(3):329-41. doi: 10.1016/j.immuni.2014.01.010. Epub 2014 Feb 20. Review.

PMID:
24560620
[PubMed - indexed for MEDLINE]
17.

Expression of the p60 autolysin enhances NK cell activation and is required for listeria monocytogenes expansion in IFN-gamma-responsive mice.

Humann J, Bjordahl R, Andreasen K, Lenz LL.

J Immunol. 2007 Feb 15;178(4):2407-14.

PMID:
17277147
[PubMed - indexed for MEDLINE]
Free Article
18.

MPYS/STING-mediated TNF-α, not type I IFN, is essential for the mucosal adjuvant activity of (3'-5')-cyclic-di-guanosine-monophosphate in vivo.

Blaauboer SM, Gabrielle VD, Jin L.

J Immunol. 2014 Jan 1;192(1):492-502. doi: 10.4049/jimmunol.1301812. Epub 2013 Dec 4.

PMID:
24307739
[PubMed - indexed for MEDLINE]
19.

The overlapping host responses to bacterial cyclic dinucleotides.

Abdul-Sater AA, Grajkowski A, Erdjument-Bromage H, Plumlee C, Levi A, Schreiber MT, Lee C, Shuman H, Beaucage SL, Schindler C.

Microbes Infect. 2012 Feb;14(2):188-97. doi: 10.1016/j.micinf.2011.09.002. Epub 2011 Sep 10.

PMID:
21933720
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Cyclic di-GMP sensing via the innate immune signaling protein STING.

Yin Q, Tian Y, Kabaleeswaran V, Jiang X, Tu D, Eck MJ, Chen ZJ, Wu H.

Mol Cell. 2012 Jun 29;46(6):735-45. doi: 10.1016/j.molcel.2012.05.029. Epub 2012 Jun 14.

PMID:
22705373
[PubMed - indexed for MEDLINE]
Free PMC Article

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