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Results: 1 to 20 of 107

1.

Characterization of two methylenedioxy bridge-forming cytochrome P450-dependent enzymes of alkaloid formation in the Mexican prickly poppy Argemone mexicana.

Díaz Chávez ML, Rolf M, Gesell A, Kutchan TM.

Arch Biochem Biophys. 2011 Mar 1;507(1):186-93. doi: 10.1016/j.abb.2010.11.016. Epub 2010 Nov 20.

PMID:
21094631
[PubMed - indexed for MEDLINE]
2.

Molecular cloning and characterization of methylenedioxy bridge-forming enzymes involved in stylopine biosynthesis in Eschscholzia californica.

Ikezawa N, Iwasa K, Sato F.

FEBS J. 2007 Feb;274(4):1019-35. Epub 2007 Jan 22.

PMID:
17250743
[PubMed - indexed for MEDLINE]
3.

Molecular cloning and characterization of CYP719, a methylenedioxy bridge-forming enzyme that belongs to a novel P450 family, from cultured Coptis japonica cells.

Ikezawa N, Tanaka M, Nagayoshi M, Shinkyo R, Sakaki T, Inouye K, Sato F.

J Biol Chem. 2003 Oct 3;278(40):38557-65. Epub 2003 May 5.

PMID:
12732624
[PubMed - indexed for MEDLINE]
Free Article
4.

CYP719A subfamily of cytochrome P450 oxygenases and isoquinoline alkaloid biosynthesis in Eschscholzia californica.

Ikezawa N, Iwasa K, Sato F.

Plant Cell Rep. 2009 Jan;28(1):123-33. doi: 10.1007/s00299-008-0624-8. Epub 2008 Oct 15.

PMID:
18854999
[PubMed - indexed for MEDLINE]
5.

Heterologous expression of two FAD-dependent oxidases with (S)-tetrahydroprotoberberine oxidase activity from Arge mone mexicana and Berberis wilsoniae in insect cells.

Gesell A, Chávez ML, Kramell R, Piotrowski M, Macheroux P, Kutchan TM.

Planta. 2011 Jun;233(6):1185-97. doi: 10.1007/s00425-011-1357-4. Epub 2011 Feb 15.

PMID:
21327819
[PubMed - indexed for MEDLINE]
6.

Molecular cloning and characterization of tetrahydroprotoberberine cis-N-methyltransferase, an enzyme involved in alkaloid biosynthesis in opium poppy.

Liscombe DK, Facchini PJ.

J Biol Chem. 2007 May 18;282(20):14741-51. Epub 2007 Mar 27.

PMID:
17389594
[PubMed - indexed for MEDLINE]
Free Article
7.

CYP719B1 is salutaridine synthase, the C-C phenol-coupling enzyme of morphine biosynthesis in opium poppy.

Gesell A, Rolf M, Ziegler J, Díaz Chávez ML, Huang FC, Kutchan TM.

J Biol Chem. 2009 Sep 4;284(36):24432-42. doi: 10.1074/jbc.M109.033373. Epub 2009 Jun 30.

PMID:
19567876
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Cloning and characterization of canadine synthase involved in noscapine biosynthesis in opium poppy.

Dang TT, Facchini PJ.

FEBS Lett. 2014 Jan 3;588(1):198-204. doi: 10.1016/j.febslet.2013.11.037. Epub 2013 Dec 4.

PMID:
24316226
[PubMed - indexed for MEDLINE]
9.

Molecular cloning and characterization of a cytochrome P450 in sanguinarine biosynthesis from Eschscholzia californica cells.

Takemura T, Ikezawa N, Iwasa K, Sato F.

Phytochemistry. 2013 Jul;91:100-8. doi: 10.1016/j.phytochem.2012.02.013. Epub 2012 Mar 13.

PMID:
22421633
[PubMed - indexed for MEDLINE]
11.

Characterization of a flavoprotein oxidase from opium poppy catalyzing the final steps in sanguinarine and papaverine biosynthesis.

Hagel JM, Beaudoin GA, Fossati E, Ekins A, Martin VJ, Facchini PJ.

J Biol Chem. 2012 Dec 14;287(51):42972-83. doi: 10.1074/jbc.M112.420414. Epub 2012 Nov 1.

PMID:
23118227
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Isolation and characterization of a cDNA encoding (S)-cis-N-methylstylopine 14-hydroxylase from opium poppy, a key enzyme in sanguinarine biosynthesis.

Beaudoin GA, Facchini PJ.

Biochem Biophys Res Commun. 2013 Feb 15;431(3):597-603. doi: 10.1016/j.bbrc.2012.12.129. Epub 2013 Jan 9.

PMID:
23313486
[PubMed - indexed for MEDLINE]
13.

Distribution of morphinan and benzo[c]phenanthridine alkaloid gene transcript accumulation in Papaver somninferum.

Huang FC, Kutchan TM.

Phytochemistry. 2000 Mar;53(5):555-64.

PMID:
10724180
[PubMed - indexed for MEDLINE]
14.

Cloning and heterologous expression of NADPH-cytochrome P450 reductases from the Papaveraceae.

Rosco A, Pauli HH, Priesner W, Kutchan TM.

Arch Biochem Biophys. 1997 Dec 15;348(2):369-77.

PMID:
9434750
[PubMed - indexed for MEDLINE]
15.

Dioxygenases catalyze O-demethylation and O,O-demethylenation with widespread roles in benzylisoquinoline alkaloid metabolism in opium poppy.

Farrow SC, Facchini PJ.

J Biol Chem. 2013 Oct 4;288(40):28997-9012. doi: 10.1074/jbc.M113.488585. Epub 2013 Aug 8.

PMID:
23928311
[PubMed - indexed for MEDLINE]
16.

The sequential exposure to jasmonate, salicylic acid and yeast extract promotes sanguinarine accumulation in Argemone mexicana cell cultures.

Trujillo-Villanueva K, Rubio-Piña J, Monforte-González M, Ramírez-Benítez E, Vázquez-Flota F.

Biotechnol Lett. 2012 Feb;34(2):379-85. doi: 10.1007/s10529-011-0770-x. Epub 2011 Oct 19.

PMID:
22009570
[PubMed - indexed for MEDLINE]
17.

Sanguinarine biosynthesis is associated with the endoplasmic reticulum in cultured opium poppy cells after elicitor treatment.

Alcantara J, Bird DA, Franceschi VR, Facchini PJ.

Plant Physiol. 2005 May;138(1):173-83. Epub 2005 Apr 22.

PMID:
15849302
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Heterologous expression of alkaloid biosynthetic genes--a review.

Kutchan TM.

Gene. 1996 Nov 7;179(1):73-81.

PMID:
8955631
[PubMed - indexed for MEDLINE]
19.

Metabolism of sanguinarine in human and in rat: characterization of oxidative metabolites produced by human CYP1A1 and CYP1A2 and rat liver microsomes using liquid chromatography-tandem mass spectrometry.

Deroussent A, Ré M, Hoellinger H, Cresteil T.

J Pharm Biomed Anal. 2010 Jul 8;52(3):391-7. doi: 10.1016/j.jpba.2009.09.014. Epub 2009 Sep 16.

PMID:
19804952
[PubMed - indexed for MEDLINE]
20.

Berberine bridge enzyme catalyzes the six electron oxidation of (S)-reticuline to dehydroscoulerine.

Winkler A, Puhl M, Weber H, Kutchan TM, Gruber K, Macheroux P.

Phytochemistry. 2009 Jun;70(9):1092-7. doi: 10.1016/j.phytochem.2009.06.005. Epub 2009 Jun 29.

PMID:
19570558
[PubMed - indexed for MEDLINE]

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