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In vivo deficiency of both C/EBPβ and C/EBPε results in highly defective myeloid differentiation and lack of cytokine response.

Akagi T, Thoennissen NH, George A, Crooks G, Song JH, Okamoto R, Nowak D, Gombart AF, Koeffler HP.

PLoS One. 2010 Nov 3;5(11):e15419. doi: 10.1371/journal.pone.0015419.


Inflammatory cytokine production by human neutrophils involves C/EBP transcription factors.

Cloutier A, Guindi C, Larivée P, Dubois CM, Amrani A, McDonald PP.

J Immunol. 2009 Jan 1;182(1):563-71.


Aberrant expression of neutrophil and macrophage-related genes in a murine model for human neutrophil-specific granule deficiency.

Gombart AF, Krug U, O'Kelly J, An E, Vegesna V, Koeffler HP.

J Leukoc Biol. 2005 Nov;78(5):1153-65. Epub 2005 Oct 4.


C/EBPepsilon directs granulocytic-vs-monocytic lineage determination and confers chemotactic function via Hlx.

Halene S, Gaines P, Sun H, Zibello T, Lin S, Khanna-Gupta A, Williams SC, Perkins A, Krause D, Berliner N.

Exp Hematol. 2010 Feb;38(2):90-103. doi: 10.1016/j.exphem.2009.11.004. Epub 2009 Dec 5.


Pro-inflammatory gene expression and neurotoxic effects of activated microglia are attenuated by absence of CCAAT/enhancer binding protein β.

Straccia M, Gresa-Arribas N, Dentesano G, Ejarque-Ortiz A, Tusell JM, Serratosa J, Solà C, Saura J.

J Neuroinflammation. 2011 Nov 10;8:156. doi: 10.1186/1742-2094-8-156.


Regulation of neutrophil and eosinophil secondary granule gene expression by transcription factors C/EBP epsilon and PU.1.

Gombart AF, Kwok SH, Anderson KL, Yamaguchi Y, Torbett BE, Koeffler HP.

Blood. 2003 Apr 15;101(8):3265-73. Epub 2002 Dec 19.


Impaired response to GM-CSF and G-CSF, and enhanced apoptosis in C/EBPbeta-deficient hematopoietic cells.

Akagi T, Saitoh T, O'Kelly J, Akira S, Gombart AF, Koeffler HP.

Blood. 2008 Mar 15;111(6):2999-3004. Epub 2007 Dec 4.


Col1a1 promoter-targeted expression of p20 CCAAT enhancer-binding protein beta (C/EBPbeta), a truncated C/EBPbeta isoform, causes osteopenia in transgenic mice.

Harrison JR, Huang YF, Wilson KA, Kelly PL, Adams DJ, Gronowicz GA, Clark SH.

J Biol Chem. 2005 Mar 4;280(9):8117-24. Epub 2004 Dec 14.


Essential role of STAT3 in the control of the acute-phase response as revealed by inducible gene inactivation [correction of activation] in the liver.

Alonzi T, Maritano D, Gorgoni B, Rizzuto G, Libert C, Poli V.

Mol Cell Biol. 2001 Mar;21(5):1621-32. Erratum in: Mol Cell Biol 2001 Apr;21(8):2967.


Critical role for transcription factor C/EBP-beta in regulating the expression of death-associated protein kinase 1.

Gade P, Roy SK, Li H, Nallar SC, Kalvakolanu DV.

Mol Cell Biol. 2008 Apr;28(8):2528-48. doi: 10.1128/MCB.00784-07. Epub 2008 Feb 4.


Transcription of Tnfaip3 is regulated by NF-κB and p38 via C/EBPβ in activated macrophages.

Lai TY, Wu SD, Tsai MH, Chuang EY, Chuang LL, Hsu LC, Lai LC.

PLoS One. 2013 Sep 2;8(9):e73153. doi: 10.1371/journal.pone.0073153. eCollection 2013.


CCAAT/enhancer-binding protein β expressed by bone marrow mesenchymal stromal cells regulates early B-cell lymphopoiesis.

Yoshioka S, Miura Y, Yao H, Satake S, Hayashi Y, Tamura A, Hishita T, Ichinohe T, Hirai H, Takaor-Kondo A, Maekawa T.

Stem Cells. 2014 Mar;32(3):730-40. doi: 10.1002/stem.1555.


Deficiency of CCAAT/enhancer binding protein-epsilon reduces atherosclerotic lesions in LDLR-/- mice.

Okamoto R, Gery S, Gombart AF, Wang X, Castellani LW, Akagi T, Chen S, Arditi M, Ho Q, Lusis AJ, Li Q, Koeffler HP.

PLoS One. 2014 Jan 28;9(1):e85341. doi: 10.1371/journal.pone.0085341. eCollection 2014.


Growth factor independence-1 (Gfi-1) plays a role in mediating specific granule deficiency (SGD) in a patient lacking a gene-inactivating mutation in the C/EBPepsilon gene.

Khanna-Gupta A, Sun H, Zibello T, Lee HM, Dahl R, Boxer LA, Berliner N.

Blood. 2007 May 15;109(10):4181-90. Epub 2007 Jan 23.

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