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Results: 1 to 20 of 165

1.

The association of AMPK with ULK1 regulates autophagy.

Lee JW, Park S, Takahashi Y, Wang HG.

PLoS One. 2010 Nov 3;5(11):e15394. doi: 10.1371/journal.pone.0015394.

PMID:
21072212
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1.

Kim J, Kundu M, Viollet B, Guan KL.

Nat Cell Biol. 2011 Feb;13(2):132-41. doi: 10.1038/ncb2152. Epub 2011 Jan 23.

PMID:
21258367
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

The serine/threonine kinase ULK1 is a target of multiple phosphorylation events.

Bach M, Larance M, James DE, Ramm G.

Biochem J. 2011 Dec 1;440(2):283-91. doi: 10.1042/BJ20101894.

PMID:
21819378
[PubMed - indexed for MEDLINE]
Free Article
4.

AMPK-dependent phosphorylation of ULK1 regulates ATG9 localization.

Mack HI, Zheng B, Asara JM, Thomas SM.

Autophagy. 2012 Aug;8(8):1197-214. doi: 10.4161/auto.20586. Epub 2012 Aug 1.

PMID:
22932492
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Ulk1-mediated phosphorylation of AMPK constitutes a negative regulatory feedback loop.

Löffler AS, Alers S, Dieterle AM, Keppeler H, Franz-Wachtel M, Kundu M, Campbell DG, Wesselborg S, Alessi DR, Stork B.

Autophagy. 2011 Jul;7(7):696-706. Epub 2011 Jul 1.

PMID:
21460634
[PubMed - indexed for MEDLINE]
Free Article
6.

ULK1 plays a critical role in AMPK-mediated myocardial autophagy and contractile dysfunction following acute alcohol challenge.

Kandadi MR, Hu N, Ren J.

Curr Pharm Des. 2013;19(27):4874-87.

PMID:
23448468
[PubMed - indexed for MEDLINE]
7.

Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy.

Egan DF, Shackelford DB, Mihaylova MM, Gelino S, Kohnz RA, Mair W, Vasquez DS, Joshi A, Gwinn DM, Taylor R, Asara JM, Fitzpatrick J, Dillin A, Viollet B, Kundu M, Hansen M, Shaw RJ.

Science. 2011 Jan 28;331(6016):456-61. doi: 10.1126/science.1196371. Epub 2010 Dec 23.

PMID:
21205641
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Alcohol and PRAS40 knockdown decrease mTOR activity and protein synthesis via AMPK signaling and changes in mTORC1 interaction.

Hong-Brown LQ, Brown CR, Kazi AA, Huber DS, Pruznak AM, Lang CH.

J Cell Biochem. 2010 Apr 15;109(6):1172-84. doi: 10.1002/jcb.22496.

PMID:
20127721
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

LKB1 and AMP-activated protein kinase control of mTOR signalling and growth.

Shaw RJ.

Acta Physiol (Oxf). 2009 May;196(1):65-80. doi: 10.1111/j.1748-1716.2009.01972.x. Epub 2009 Feb 19. Review.

PMID:
19245654
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Nutrient starvation elicits an acute autophagic response mediated by Ulk1 dephosphorylation and its subsequent dissociation from AMPK.

Shang L, Chen S, Du F, Li S, Zhao L, Wang X.

Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):4788-93. doi: 10.1073/pnas.1100844108. Epub 2011 Mar 7.

PMID:
21383122
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

ULK1 inhibits mTORC1 signaling, promotes multisite Raptor phosphorylation and hinders substrate binding.

Dunlop EA, Hunt DK, Acosta-Jaquez HA, Fingar DC, Tee AR.

Autophagy. 2011 Jul;7(7):737-47. Epub 2011 Jul 1.

PMID:
21460630
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR.

Egan D, Kim J, Shaw RJ, Guan KL.

Autophagy. 2011 Jun;7(6):643-4. Epub 2011 Jun 1.

PMID:
21460621
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Regulation of the autophagy initiating kinase ULK1 by nutrients: roles of mTORC1 and AMPK.

Kim J, Guan KL.

Cell Cycle. 2011 May 1;10(9):1337-8. doi: 10.4161/cc.10.9.15291. Epub 2011 Mar 15.

PMID:
21403467
[PubMed - indexed for MEDLINE]
Free Article
14.

AMPK promotes skeletal muscle autophagy through activation of forkhead FoxO3a and interaction with Ulk1.

Sanchez AM, Csibi A, Raibon A, Cornille K, Gay S, Bernardi H, Candau R.

J Cell Biochem. 2012 Feb;113(2):695-710. doi: 10.1002/jcb.23399.

PMID:
22006269
[PubMed - indexed for MEDLINE]
15.

Inhibition of mTOR kinase by AZD8055 can antagonize chemotherapy-induced cell death through autophagy induction and down-regulation of p62/sequestosome 1.

Huang S, Yang ZJ, Yu C, Sinicrope FA.

J Biol Chem. 2011 Nov 18;286(46):40002-12. doi: 10.1074/jbc.M111.297432. Epub 2011 Sep 23.

PMID:
21949121
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Deficiency in AMPK attenuates ethanol-induced cardiac contractile dysfunction through inhibition of autophagosome formation.

Guo R, Ren J.

Cardiovasc Res. 2012 Jun 1;94(3):480-91. doi: 10.1093/cvr/cvs127. Epub 2012 Mar 26.

PMID:
22451512
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Binding of the Atg1/ULK1 kinase to the ubiquitin-like protein Atg8 regulates autophagy.

Kraft C, Kijanska M, Kalie E, Siergiejuk E, Lee SS, Semplicio G, Stoffel I, Brezovich A, Verma M, Hansmann I, Ammerer G, Hofmann K, Tooze S, Peter M.

EMBO J. 2012 Sep 12;31(18):3691-703. doi: 10.1038/emboj.2012.225. Epub 2012 Aug 10.

PMID:
22885598
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

AMPK and mTOR coordinate the regulation of Ulk1 and mammalian autophagy initiation.

Shang L, Wang X.

Autophagy. 2011 Aug;7(8):924-6. Epub 2011 Aug 1.

PMID:
21521945
[PubMed - indexed for MEDLINE]
Free Article
19.

Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy.

Hosokawa N, Hara T, Kaizuka T, Kishi C, Takamura A, Miura Y, Iemura S, Natsume T, Takehana K, Yamada N, Guan JL, Oshiro N, Mizushima N.

Mol Biol Cell. 2009 Apr;20(7):1981-91. doi: 10.1091/mbc.E08-12-1248. Epub 2009 Feb 11.

PMID:
19211835
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Role of an intrinsically disordered conformation in AMPK-mediated phosphorylation of ULK1 and regulation of autophagy.

Khan SH, Kumar R.

Mol Biosyst. 2012 Jan;8(1):91-6. doi: 10.1039/c1mb05265a. Epub 2011 Aug 18. Review.

PMID:
21853163
[PubMed - indexed for MEDLINE]

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