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Results: 1 to 20 of 98

1.

A genome-wide RNAi screen identifies multiple RSK-dependent regulators of cell migration.

Smolen GA, Zhang J, Zubrowski MJ, Edelman EJ, Luo B, Yu M, Ng LW, Scherber CM, Schott BJ, Ramaswamy S, Irimia D, Root DE, Haber DA.

Genes Dev. 2010 Dec 1;24(23):2654-65. doi: 10.1101/gad.1989110. Epub 2010 Nov 9.

PMID:
21062900
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Ribosomal protein S6 kinase (RSK)-2 as a central effector molecule in RON receptor tyrosine kinase mediated epithelial to mesenchymal transition induced by macrophage-stimulating protein.

Ma Q, Guin S, Padhye SS, Zhou YQ, Zhang RW, Wang MH.

Mol Cancer. 2011 May 28;10:66. doi: 10.1186/1476-4598-10-66.

PMID:
21619683
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

The epithelial-mesenchymal transition (EMT) regulatory factor SLUG (SNAI2) is a downstream target of SPARC and AKT in promoting melanoma cell invasion.

Fenouille N, Tichet M, Dufies M, Pottier A, Mogha A, Soo JK, Rocchi S, Mallavialle A, Galibert MD, Khammari A, Lacour JP, Ballotti R, Deckert M, Tartare-Deckert S.

PLoS One. 2012;7(7):e40378. doi: 10.1371/journal.pone.0040378. Epub 2012 Jul 20.

PMID:
22911700
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Wild-type and mutant p53 differentially regulate NADPH oxidase 4 in TGF-β-mediated migration of human lung and breast epithelial cells.

Boudreau HE, Casterline BW, Burke DJ, Leto TL.

Br J Cancer. 2014 May 13;110(10):2569-82. doi: 10.1038/bjc.2014.165. Epub 2014 Apr 8.

PMID:
24714748
[PubMed - indexed for MEDLINE]
5.

RBM5/H37 tumor suppressor, located at the lung cancer hot spot 3p21.3, alters expression of genes involved in metastasis.

Oh JJ, Taschereau EO, Koegel AK, Ginther CL, Rotow JK, Isfahani KZ, Slamon DJ.

Lung Cancer. 2010 Dec;70(3):253-62. doi: 10.1016/j.lungcan.2010.02.012. Epub 2010 Mar 24.

PMID:
20338664
[PubMed - indexed for MEDLINE]
6.

Ribosomal S6 kinase (RSK) regulates phosphorylation of filamin A on an important regulatory site.

Woo MS, Ohta Y, Rabinovitz I, Stossel TP, Blenis J.

Mol Cell Biol. 2004 Apr;24(7):3025-35.

PMID:
15024089
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

High-throughput RNAi screening for novel modulators of vimentin expression identifies MTHFD2 as a regulator of breast cancer cell migration and invasion.

Lehtinen L, Ketola K, Mäkelä R, Mpindi JP, Viitala M, Kallioniemi O, Iljin K.

Oncotarget. 2013 Jan;4(1):48-63.

PMID:
23295955
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

A genome-wide RNAi screen identifies novel targets of neratinib sensitivity leading to neratinib and paclitaxel combination drug treatments.

Seyhan AA, Varadarajan U, Choe S, Liu Y, McGraw J, Woods M, Murray S, Eckert A, Liu W, Ryan TE.

Mol Biosyst. 2011 Jun;7(6):1974-89. doi: 10.1039/c0mb00294a. Epub 2011 Apr 12.

PMID:
21487605
[PubMed - indexed for MEDLINE]
9.

Targeting ribosomal S6 kinases/Y-box binding protein-1 signaling improves cellular sensitivity to taxane in prostate cancer.

Shiota M, Itsumi M, Yokomizo A, Takeuchi A, Imada K, Kashiwagi E, Inokuchi J, Tatsugami K, Uchiumi T, Naito S.

Prostate. 2014 Jun;74(8):829-38. doi: 10.1002/pros.22799. Epub 2014 Apr 12.

PMID:
24729449
[PubMed - indexed for MEDLINE]
10.

RSK is a principal effector of the RAS-ERK pathway for eliciting a coordinate promotile/invasive gene program and phenotype in epithelial cells.

Doehn U, Hauge C, Frank SR, Jensen CJ, Duda K, Nielsen JV, Cohen MS, Johansen JV, Winther BR, Lund LR, Winther O, Taunton J, Hansen SH, Frödin M.

Mol Cell. 2009 Aug 28;35(4):511-22. doi: 10.1016/j.molcel.2009.08.002.

PMID:
19716794
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Differential roles of ERK and Akt pathways in regulation of EGFR-mediated signaling and motility in prostate cancer cells.

Gan Y, Shi C, Inge L, Hibner M, Balducci J, Huang Y.

Oncogene. 2010 Sep 2;29(35):4947-58. doi: 10.1038/onc.2010.240. Epub 2010 Jun 21.

PMID:
20562913
[PubMed - indexed for MEDLINE]
12.

Insulin receptor substrate-1 suppresses transforming growth factor-beta1-mediated epithelial-mesenchymal transition.

Shi J, Wang DM, Wang CM, Hu Y, Liu AH, Zhang YL, Sun B, Song JG.

Cancer Res. 2009 Sep 15;69(18):7180-7. doi: 10.1158/0008-5472.CAN-08-4470. Epub 2009 Sep 8.

PMID:
19738073
[PubMed - indexed for MEDLINE]
Free Article
13.

Extracellular remodelling during oncogenic Ras-induced epithelial-mesenchymal transition facilitates MDCK cell migration.

Mathias RA, Chen YS, Wang B, Ji H, Kapp EA, Moritz RL, Zhu HJ, Simpson RJ.

J Proteome Res. 2010 Feb 5;9(2):1007-19. doi: 10.1021/pr900907g.

PMID:
19954229
[PubMed - indexed for MEDLINE]
14.

The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition.

Dissanayake SK, Wade M, Johnson CE, O'Connell MP, Leotlela PD, French AD, Shah KV, Hewitt KJ, Rosenthal DT, Indig FE, Jiang Y, Nickoloff BJ, Taub DD, Trent JM, Moon RT, Bittner M, Weeraratna AT.

J Biol Chem. 2007 Jun 8;282(23):17259-71. Epub 2007 Apr 10.

PMID:
17426020
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Down-regulation of CMTM8 induces epithelial-to-mesenchymal transition-like changes via c-MET/extracellular signal-regulated kinase (ERK) signaling.

Zhang W, Mendoza MC, Pei X, Ilter D, Mahoney SJ, Zhang Y, Ma D, Blenis J, Wang Y.

J Biol Chem. 2012 Apr 6;287(15):11850-8. doi: 10.1074/jbc.M111.258236. Epub 2012 Feb 15.

PMID:
22337876
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Breast tumor kinase and extracellular signal-regulated kinase 5 mediate Met receptor signaling to cell migration in breast cancer cells.

Castro NE, Lange CA.

Breast Cancer Res. 2010;12(4):R60. doi: 10.1186/bcr2622. Epub 2010 Aug 5.

PMID:
20687930
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

IGF2BP1 promotes mesenchymal cell properties and migration of tumor-derived cells by enhancing the expression of LEF1 and SNAI2 (SLUG).

Zirkel A, Lederer M, Stöhr N, Pazaitis N, Hüttelmaier S.

Nucleic Acids Res. 2013 Jul;41(13):6618-36. doi: 10.1093/nar/gkt410. Epub 2013 May 15.

PMID:
23677615
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

A small interfering RNA screen for modulators of tumor cell motility identifies MAP4K4 as a promigratory kinase.

Collins CS, Hong J, Sapinoso L, Zhou Y, Liu Z, Micklash K, Schultz PG, Hampton GM.

Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3775-80. Epub 2006 Feb 28.

PMID:
16537454
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Differential roles of Src in transforming growth factor-ß regulation of growth arrest, epithelial-to-mesenchymal transition and cell migration in pancreatic ductal adenocarcinoma cells.

Ungefroren H, Sebens S, Groth S, Gieseler F, Fändrich F.

Int J Oncol. 2011 Mar;38(3):797-805. doi: 10.3892/ijo.2011.897. Epub 2011 Jan 11.

PMID:
21225226
[PubMed - indexed for MEDLINE]
20.

UVA induces Ser381 phosphorylation of p90RSK/MAPKAP-K1 via ERK and JNK pathways.

Zhang Y, Zhong S, Dong Z, Chen N, Bode AM, Ma W, Dong Z.

J Biol Chem. 2001 May 4;276(18):14572-80. Epub 2001 Jan 31.

PMID:
11278279
[PubMed - indexed for MEDLINE]
Free Article

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