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Items: 1 to 20 of 83

1.

EphB-mediated degradation of the RhoA GEF Ephexin5 relieves a developmental brake on excitatory synapse formation.

Margolis SS, Salogiannis J, Lipton DM, Mandel-Brehm C, Wills ZP, Mardinly AR, Hu L, Greer PL, Bikoff JB, Ho HY, Soskis MJ, Sahin M, Greenberg ME.

Cell. 2010 Oct 29;143(3):442-55. doi: 10.1016/j.cell.2010.09.038.

2.

The Angelman Syndrome protein Ube3A regulates synapse development by ubiquitinating arc.

Greer PL, Hanayama R, Bloodgood BL, Mardinly AR, Lipton DM, Flavell SW, Kim TK, Griffith EC, Waldon Z, Maehr R, Ploegh HL, Chowdhury S, Worley PF, Steen J, Greenberg ME.

Cell. 2010 Mar 5;140(5):704-16. doi: 10.1016/j.cell.2010.01.026.

3.

Postsynaptic density scaffold SAP102 regulates cortical synapse development through EphB and PAK signaling pathway.

Murata Y, Constantine-Paton M.

J Neurosci. 2013 Mar 13;33(11):5040-52. doi: 10.1523/JNEUROSCI.2896-12.2013.

4.

EphB receptors interact with NMDA receptors and regulate excitatory synapse formation.

Dalva MB, Takasu MA, Lin MZ, Shamah SM, Hu L, Gale NW, Greenberg ME.

Cell. 2000 Dec 8;103(6):945-56.

5.

EphB receptors regulate dendritic spine morphogenesis through the recruitment/phosphorylation of focal adhesion kinase and RhoA activation.

Moeller ML, Shi Y, Reichardt LF, Ethell IM.

J Biol Chem. 2006 Jan 20;281(3):1587-98. Epub 2005 Nov 18.

6.

IL1RAPL1 associated with mental retardation and autism regulates the formation and stabilization of glutamatergic synapses of cortical neurons through RhoA signaling pathway.

Hayashi T, Yoshida T, Ra M, Taguchi R, Mishina M.

PLoS One. 2013 Jun 13;8(6):e66254. doi: 10.1371/journal.pone.0066254. Print 2013.

7.

Expression of the Rho-GEF Pbl/ECT2 is regulated by the UBE3A E3 ubiquitin ligase.

Reiter LT, Seagroves TN, Bowers M, Bier E.

Hum Mol Genet. 2006 Sep 15;15(18):2825-35. Epub 2006 Aug 11.

8.

An LRRTM4-HSPG complex mediates excitatory synapse development on dentate gyrus granule cells.

Siddiqui TJ, Tari PK, Connor SA, Zhang P, Dobie FA, She K, Kawabe H, Wang YT, Brose N, Craig AM.

Neuron. 2013 Aug 21;79(4):680-95. doi: 10.1016/j.neuron.2013.06.029. Epub 2013 Aug 1.

9.

Rapid induction of dendritic spine morphogenesis by trans-synaptic ephrinB-EphB receptor activation of the Rho-GEF kalirin.

Penzes P, Beeser A, Chernoff J, Schiller MR, Eipper BA, Mains RE, Huganir RL.

Neuron. 2003 Jan 23;37(2):263-74.

10.
11.

The Angelman syndrome ubiquitin ligase localizes to the synapse and nucleus, and maternal deficiency results in abnormal dendritic spine morphology.

Dindot SV, Antalffy BA, Bhattacharjee MB, Beaudet AL.

Hum Mol Genet. 2008 Jan 1;17(1):111-8. Epub 2007 Oct 16.

12.

An Autism-Linked Mutation Disables Phosphorylation Control of UBE3A.

Yi JJ, Berrios J, Newbern JM, Snider WD, Philpot BD, Hahn KM, Zylka MJ.

Cell. 2015 Aug 13;162(4):795-807. doi: 10.1016/j.cell.2015.06.045. Epub 2015 Aug 6.

13.

The role of calcium-dependent gene expression in autism spectrum disorders: lessons from MeCP2, Ube3a and beyond.

Qiu Z, Cheng J.

Neurosignals. 2010;18(2):72-81. doi: 10.1159/000320970. Epub 2010 Oct 19. Review.

PMID:
20956852
14.

Changes in mGlu5 receptor-dependent synaptic plasticity and coupling to homer proteins in the hippocampus of Ube3A hemizygous mice modeling angelman syndrome.

Pignatelli M, Piccinin S, Molinaro G, Di Menna L, Riozzi B, Cannella M, Motolese M, Vetere G, Catania MV, Battaglia G, Nicoletti F, Nisticò R, Bruno V.

J Neurosci. 2014 Mar 26;34(13):4558-66. doi: 10.1523/JNEUROSCI.1846-13.2014.

15.

Ephecting excitatory synapse development.

Dalva MB.

Cell. 2010 Oct 29;143(3):341-2. doi: 10.1016/j.cell.2010.10.017.

16.

Binding of RhoA by the C2 domain of E3 ligase Smurf1 is essential for Smurf1-regulated RhoA ubiquitination and cell protrusive activity.

Tian M, Bai C, Lin Q, Lin H, Liu M, Ding F, Wang HR.

FEBS Lett. 2011 Jul 21;585(14):2199-204. doi: 10.1016/j.febslet.2011.06.016. Epub 2011 Jun 23.

17.

Serine phosphorylation of ephrinB2 regulates trafficking of synaptic AMPA receptors.

Essmann CL, Martinez E, Geiger JC, Zimmer M, Traut MH, Stein V, Klein R, Acker-Palmer A.

Nat Neurosci. 2008 Sep;11(9):1035-43. doi: 10.1038/nn.2171.

PMID:
19160501
18.

Neuroscience: Angelman syndrome connections.

Scheiffele P, Beg AA.

Nature. 2010 Dec 16;468(7326):907-8. doi: 10.1038/468907a. No abstract available.

PMID:
21164477
19.

EphB controls NMDA receptor function and synaptic targeting in a subunit-specific manner.

Nolt MJ, Lin Y, Hruska M, Murphy J, Sheffler-Colins SI, Kayser MS, Passer J, Bennett MV, Zukin RS, Dalva MB.

J Neurosci. 2011 Apr 6;31(14):5353-64. doi: 10.1523/JNEUROSCI.0282-11.2011.

20.

Intracellular and trans-synaptic regulation of glutamatergic synaptogenesis by EphB receptors.

Kayser MS, McClelland AC, Hughes EG, Dalva MB.

J Neurosci. 2006 Nov 22;26(47):12152-64.

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