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Results: 1 to 20 of 121

1.

Pervasive cryptic epistasis in molecular evolution.

Lunzer M, Golding GB, Dean AM.

PLoS Genet. 2010 Oct 21;6(10):e1001162. doi: 10.1371/journal.pgen.1001162. Erratum in: PLoS Genet. 2010;6(11). doi: 10.1371/annotation/d618ce28-5010-47df-a44e-148ecdc0fef6.

PMID:
20975933
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The biochemical architecture of an ancient adaptive landscape.

Lunzer M, Miller SP, Felsheim R, Dean AM.

Science. 2005 Oct 21;310(5747):499-501.

PMID:
16239478
[PubMed - indexed for MEDLINE]
Free Article
3.

Direct demonstration of an adaptive constraint.

Miller SP, Lunzer M, Dean AM.

Science. 2006 Oct 20;314(5798):458-61.

PMID:
17053145
[PubMed - indexed for MEDLINE]
Free Article
4.

Structural insights into the UbiD protein family from the crystal structure of PA0254 from Pseudomonas aeruginosa.

Jacewicz A, Izumi A, Brunner K, Schnell R, Schneider G.

PLoS One. 2013 May 9;8(5):e63161. doi: 10.1371/journal.pone.0063161. Print 2013.

PMID:
23671667
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Exploring substrate binding and discrimination in fructose1, 6-bisphosphate and tagatose 1,6-bisphosphate aldolases.

Zgiby SM, Thomson GJ, Qamar S, Berry A.

Eur J Biochem. 2000 Mar;267(6):1858-68.

PMID:
10712619
[PubMed - indexed for MEDLINE]
Free Article
6.

Site-directed mutagenesis and phylogenetic comparisons of the Escherichia coli Tus protein: DNA-protein interactions alone can not account for Tus activity.

Henderson TA, Nilles AF, Valjavec-Gratian M, Hill TM.

Mol Genet Genomics. 2001 Aug;265(6):941-53.

PMID:
11523786
[PubMed - indexed for MEDLINE]
7.

Characterization of DNA-binding specificity and analysis of binding sites of the Pseudomonas aeruginosa global regulator, Vfr, a homologue of the Escherichia coli cAMP receptor protein.

Kanack KJ, Runyen-Janecky LJ, Ferrell EP, Suh SJ, West SE.

Microbiology. 2006 Dec;152(Pt 12):3485-96.

PMID:
17159200
[PubMed - indexed for MEDLINE]
Free Article
8.

The Pseudomonas aeruginosa initiation factor IF-2 is responsible for formylation-independent protein initiation in P. aeruginosa.

Steiner-Mosonyi M, Creuzenet C, Keates RA, Strub BR, Mangroo D.

J Biol Chem. 2004 Dec 10;279(50):52262-9. Epub 2004 Sep 22.

PMID:
15385567
[PubMed - indexed for MEDLINE]
Free Article
9.

Site-directed mutations and kinetic studies show key residues involved in alkylammonium interactions and reveal two sites for phosphorylcholine in Pseudomonas aeruginosa phosphorylcholine phosphatase.

Beassoni PR, Otero LH, Boetsch C, Domenech CE, González-Nilo FD, Lisa AT.

Biochim Biophys Acta. 2011 Jul;1814(7):858-63. doi: 10.1016/j.bbapap.2011.04.003. Epub 2011 Apr 15.

PMID:
21515416
[PubMed - indexed for MEDLINE]
Free Article
10.

Role of the amino acid invariants in the active site of MurG as evaluated by site-directed mutagenesis.

Crouvoisier M, Auger G, Blanot D, Mengin-Lecreulx D.

Biochimie. 2007 Dec;89(12):1498-508. Epub 2007 Jul 5.

PMID:
17692452
[PubMed - indexed for MEDLINE]
11.

The PRC-barrel domain of the ribosome maturation protein RimM mediates binding to ribosomal protein S19 in the 30S ribosomal subunits.

Lövgren JM, Bylund GO, Srivastava MK, Lundberg LA, Persson OP, Wingsle G, Wikström PM.

RNA. 2004 Nov;10(11):1798-812.

PMID:
15496525
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

The C-terminal domain of biotin protein ligase from E. coli is required for catalytic activity.

Chapman-Smith A, Mulhern TD, Whelan F, Cronan JE Jr, Wallace JC.

Protein Sci. 2001 Dec;10(12):2608-17.

PMID:
11714929
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Substitutions of coenzyme-binding, nonpolar residues improve the low-temperature activity of thermophilic dehydrogenases.

Hayashi S, Akanuma S, Onuki W, Tokunaga C, Yamagishi A.

Biochemistry. 2011 Oct 11;50(40):8583-93. doi: 10.1021/bi200925f. Epub 2011 Sep 19.

PMID:
21894900
[PubMed - indexed for MEDLINE]
14.

Probing the catalytic mechanism of prephenate dehydratase by site-directed mutagenesis of the Escherichia coli P-protein dehydratase domain.

Zhang S, Wilson DB, Ganem B.

Biochemistry. 2000 Apr 25;39(16):4722-8.

PMID:
10769128
[PubMed - indexed for MEDLINE]
15.

Site-directed mutagenesis of the greasy slide aromatic residues within the LamB (maltoporin) channel of Escherichia coli: effect on ion and maltopentaose transport.

Denker K, Orlik F, Schiffler B, Benz R.

J Mol Biol. 2005 Sep 23;352(3):534-50.

PMID:
16095613
[PubMed - indexed for MEDLINE]
16.

A coevolutionary residue network at the site of a functionally important conformational change in a phosphohexomutase enzyme family.

Lee Y, Mick J, Furdui C, Beamer LJ.

PLoS One. 2012;7(6):e38114. doi: 10.1371/journal.pone.0038114. Epub 2012 Jun 7.

PMID:
22685552
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Identification of basic amino acid residues important for citrate binding by the periplasmic receptor domain of the sensor kinase CitA.

Gerharz T, Reinelt S, Kaspar S, Scapozza L, Bott M.

Biochemistry. 2003 May 20;42(19):5917-24.

PMID:
12741850
[PubMed - indexed for MEDLINE]
19.

Structure-activity relationship of a cold-adapted purine nucleoside phosphorylase by site-directed mutagenesis.

Xie X, Huo W, Xia J, Xu Q, Chen N.

Enzyme Microb Technol. 2012 Jun 10;51(1):59-65. doi: 10.1016/j.enzmictec.2012.04.002. Epub 2012 Apr 21.

PMID:
22579392
[PubMed - indexed for MEDLINE]
20.

Identification and preliminary characterization of temperature-sensitive mutations affecting HlyB, the translocator required for the secretion of haemolysin (HlyA) from Escherichia coli.

Blight MA, Pimenta AL, Lazzaroni JC, Dando C, Kotelevets L, Séror SJ, Holland IB.

Mol Gen Genet. 1994 Nov 15;245(4):431-40.

PMID:
7808392
[PubMed - indexed for MEDLINE]

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