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Items: 1 to 20 of 75

1.

Novel components of the human metabolome: the identification, characterization and anti-inflammatory activity of two 5-androstene tetrols.

Ahlem CN, Page TM, Auci DL, Kennedy MR, Mangano K, Nicoletti F, Ge Y, Huang Y, White SK, Villegas S, Conrad D, Wang A, Reading CL, Frincke JM.

Steroids. 2011 Jan;76(1-2):145-55. doi: 10.1016/j.steroids.2010.10.005. Epub 2010 Oct 23.

PMID:
20974164
2.

Pharmacology and immune modulating properties of 5-androstene-3β,7β,17β-triol, a DHEA metabolite in the human metabolome.

Ahlem CN, Auci DL, Nicoletti F, Pieters R, Kennedy MR, Page TM, Reading CL, Enioutina EY, Frincke JM.

J Steroid Biochem Mol Biol. 2011 Sep;126(3-5):87-94. doi: 10.1016/j.jsbmb.2011.04.010. Epub 2011 May 5.

PMID:
21570467
3.

Studies of the pharmacology of 17α-ethynyl-androst-5-ene-3β,7β,17β-triol, a synthetic anti-inflammatory androstene.

Ahlem CN, Kennedy MR, Page TM, Reading CL, White SK, McKenzie JJ, Cole PI, Stickney DR, Frincke JM.

Int J Clin Exp Med. 2011;4(2):119-35. Epub 2011 Apr 23.

4.

HE3286: a novel synthetic steroid as an oral treatment for autoimmune disease.

Ahlem C, Auci D, Mangano K, Reading C, Frincke J, Stickney D, Nicoletti F.

Ann N Y Acad Sci. 2009 Sep;1173:781-90. doi: 10.1111/j.1749-6632.2009.04798.x.

PMID:
19758229
5.

Molecular targets for 17α-ethynyl-5-androstene-3β,7β,17β-triol, an anti-inflammatory agent derived from the human metabolome.

Reading CL, Frincke JM, White SK.

PLoS One. 2012;7(2):e32147. doi: 10.1371/journal.pone.0032147. Epub 2012 Feb 24.

6.

7-hydroxyfrullanolide, a sesquiterpene lactone, inhibits pro-inflammatory cytokine production from immune cells and is orally efficacious in animal models of inflammation.

Fonseca LC, Dadarkar SS, Lobo AS, Suthar AC, Chauhan VS, Chandrababu S, Sharma SD, Dagia NM, Padigaru M.

Eur J Pharmacol. 2010 Oct 10;644(1-3):220-9. doi: 10.1016/j.ejphar.2010.06.052. Epub 2010 Jul 13.

PMID:
20621086
8.

Efficacy of a potent and safe vitamin D receptor agonist for the treatment of inflammatory bowel disease.

Laverny G, Penna G, Vetrano S, Correale C, Nebuloni M, Danese S, Adorini L.

Immunol Lett. 2010 Jun 15;131(1):49-58. doi: 10.1016/j.imlet.2010.03.006. Epub 2010 Mar 27.

PMID:
20350569
9.

Binding characteristics of [3H]delta(5)-androstene-3beta,17beta-diol to a nuclear protein in the rabbit vagina.

Traish AM, Huang YH, Min K, Kim NN, Munarriz R, Goldstein I.

Steroids. 2004 Jan;69(1):71-8.

PMID:
14715380
10.

Blockade of adenosine A2B receptors ameliorates murine colitis.

Kolachala V, Ruble B, Vijay-Kumar M, Wang L, Mwangi S, Figler H, Figler R, Srinivasan S, Gewirtz A, Linden J, Merlin D, Sitaraman S.

Br J Pharmacol. 2008 Sep;155(1):127-37. doi: 10.1038/bjp.2008.227. Epub 2008 Jun 9.

11.

Natural anti-inflammatory compounds for the management and adjuvant therapy of inflammatory bowel disease and its drug delivery system.

Kim HJ, Neophytou C.

Arch Pharm Res. 2009 Jul;32(7):997-1004. doi: 10.1007/s12272-009-1704-1. Epub 2009 Jul 31.

PMID:
19641880
12.

Isolation and X-ray study of an anti-inflammatory active androstene steroid from Acacia nilotica.

Chaubal R, Mujumdar AM, Puranik VG, Deshpande VH, Deshpande NR.

Planta Med. 2003 Mar;69(3):287-8.

PMID:
12677540
13.

A potential role for 5-androstene-3β,7β,17β-triol in obesity and metabolic syndrome.

Auci DL, Ahlem CN, Kennedy MR, Page TM, Reading CL, Frincke JM.

Obesity (Silver Spring). 2011 Apr;19(4):806-11. doi: 10.1038/oby.2010.204. Epub 2010 Sep 16.

14.

Effect of the phytotherapeutic agent Eviprostat on 17beta-estradiol-induced nonbacterial inflammation in the rat prostate.

Oka M, Ueda M, Oyama T, Kyotani J, Tanaka M.

Prostate. 2009 Sep 15;69(13):1404-10. doi: 10.1002/pros.20985.

PMID:
19489033
15.

A fluorinated analog of ISO-1 blocks the recognition and biological function of MIF and is orally efficacious in a murine model of colitis.

Dagia NM, Kamath DV, Bhatt P, Gupte RD, Dadarkar SS, Fonseca L, Agarwal G, Chetrapal-Kunwar A, Balachandran S, Srinivasan S, Bose J, Pari K, B-Rao C, Parkale SS, Gadekar PK, Rodge AH, Mandrekar N, Vishwakarma RA, Sharma S.

Eur J Pharmacol. 2009 Apr 1;607(1-3):201-12. doi: 10.1016/j.ejphar.2009.02.031. Epub 2009 Feb 21.

PMID:
19239912
16.

5-amino salicylic acid bound nanoparticles for the therapy of inflammatory bowel disease.

Pertuit D, Moulari B, Betz T, Nadaradjane A, Neumann D, Ismaïli L, Refouvelet B, Pellequer Y, Lamprecht A.

J Control Release. 2007 Nov 20;123(3):211-8. Epub 2007 Aug 19.

PMID:
17889397
17.

Hydrogen sulphide: an increasing need for scientific equipoise.

Coffey JC, Docherty NG, O'Connell PR.

Gastroenterology. 2009 Dec;137(6):2181-2; author reply 2182. doi: 10.1053/j.gastro.2009.06.073. Epub 2009 Oct 28. No abstract available.

PMID:
19878749
18.
19.

Drug-loaded nanoparticles targeted to the colon with polysaccharide hydrogel reduce colitis in a mouse model.

Laroui H, Dalmasso G, Nguyen HT, Yan Y, Sitaraman SV, Merlin D.

Gastroenterology. 2010 Mar;138(3):843-53.e1-2. doi: 10.1053/j.gastro.2009.11.003. Epub 2009 Nov 10.

PMID:
19909746
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