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Results: 1 to 20 of 123

1.

Differential reactivity between two copper sites in peptidylglycine α-hydroxylating monooxygenase.

Chufán EE, Prigge ST, Siebert X, Eipper BA, Mains RE, Amzel LM.

J Am Chem Soc. 2010 Nov 10;132(44):15565-72. doi: 10.1021/ja103117r.

PMID:
20958070
[PubMed - indexed for MEDLINE]
Free PMC Article
2.
3.

Coordination of peroxide to the Cu(M) center of peptidylglycine α-hydroxylating monooxygenase (PHM): structural and computational study.

Rudzka K, Moreno DM, Eipper B, Mains R, Estrin DA, Amzel LM.

J Biol Inorg Chem. 2013 Feb;18(2):223-32. doi: 10.1007/s00775-012-0967-z. Epub 2012 Dec 18.

PMID:
23247335
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Binding of copper and silver to single-site variants of peptidylglycine monooxygenase reveals the structure and chemistry of the individual metal centers.

Chauhan S, Kline CD, Mayfield M, Blackburn NJ.

Biochemistry. 2014 Feb 18;53(6):1069-80. doi: 10.1021/bi4015264. Epub 2014 Feb 7.

PMID:
24471980
[PubMed - indexed for MEDLINE]
5.

The catalytic role of the copper ligand H172 of peptidylglycine alpha-hydroxylating monooxygenase (PHM): a spectroscopic study of the H172A mutant.

Jaron S, Mains RE, Eipper BA, Blackburn NJ.

Biochemistry. 2002 Nov 5;41(44):13274-82.

PMID:
12403629
[PubMed - indexed for MEDLINE]
7.

The catalytic copper of peptidylglycine alpha-hydroxylating monooxygenase also plays a critical structural role.

Siebert X, Eipper BA, Mains RE, Prigge ST, Blackburn NJ, Amzel LM.

Biophys J. 2005 Nov;89(5):3312-9. Epub 2005 Aug 12.

PMID:
16100265
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Active site models for the Cu(A) site of peptidylglycine α-hydroxylating monooxygenase and dopamine β-monooxygenase.

Kunishita A, Ertem MZ, Okubo Y, Tano T, Sugimoto H, Ohkubo K, Fujieda N, Fukuzumi S, Cramer CJ, Itoh S.

Inorg Chem. 2012 Sep 3;51(17):9465-80. doi: 10.1021/ic301272h. Epub 2012 Aug 21.

PMID:
22908844
[PubMed - indexed for MEDLINE]
9.

A copper-methionine interaction controls the pH-dependent activation of peptidylglycine monooxygenase.

Bauman AT, Broers BA, Kline CD, Blackburn NJ.

Biochemistry. 2011 Dec 20;50(50):10819-28. doi: 10.1021/bi201193j. Epub 2011 Nov 22.

PMID:
22080626
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Substrate-mediated electron transfer in peptidylglycine alpha-hydroxylating monooxygenase.

Prigge ST, Kolhekar AS, Eipper BA, Mains RE, Amzel LM.

Nat Struct Biol. 1999 Oct;6(10):976-83.

PMID:
10504734
[PubMed - indexed for MEDLINE]
11.

Does superoxide channel between the copper centers in peptidylglycine monooxygenase? A new mechanism based on carbon monoxide reactivity.

Jaron S, Blackburn NJ.

Biochemistry. 1999 Nov 16;38(46):15086-96.

PMID:
10563791
[PubMed - indexed for MEDLINE]
12.

Peptidylglycine alpha-hydroxylating monooxygenase: active site residues, disulfide linkages, and a two-domain model of the catalytic core.

Kolhekar AS, Keutmann HT, Mains RE, Quon AS, Eipper BA.

Biochemistry. 1997 Sep 9;36(36):10901-9.

PMID:
9283080
[PubMed - indexed for MEDLINE]
13.

The catalytic core of peptidylglycine alpha-hydroxylating monooxygenase: investigation by site-directed mutagenesis, Cu X-ray absorption spectroscopy, and electron paramagnetic resonance.

Eipper BA, Quon AS, Mains RE, Boswell JS, Blackburn NJ.

Biochemistry. 1995 Mar 7;34(9):2857-65.

PMID:
7893699
[PubMed - indexed for MEDLINE]
14.

Amidation of bioactive peptides: the structure of peptidylglycine alpha-hydroxylating monooxygenase.

Prigge ST, Kolhekar AS, Eipper BA, Mains RE, Amzel LM.

Science. 1997 Nov 14;278(5341):1300-5.

PMID:
9360928
[PubMed - indexed for MEDLINE]
Free Article
15.

A new proposal for the mechanism of glycine hydroxylation as catalyzed by peptidylglycine alpha-hydroxylating monooxygenase (PHM).

Owen TC, Merkler DJ.

Med Hypotheses. 2004;62(3):392-400.

PMID:
14975510
[PubMed - indexed for MEDLINE]
16.

Evidence for substrate preorganization in the peptidylglycine α-amidating monooxygenase reaction describing the contribution of ground state structure to hydrogen tunneling.

McIntyre NR, Lowe EW Jr, Belof JL, Ivkovic M, Shafer J, Space B, Merkler DJ.

J Am Chem Soc. 2010 Nov 24;132(46):16393-402. doi: 10.1021/ja1019194. Epub 2010 Nov 2.

PMID:
21043511
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Theoretical modelling of tripodal CuN3 and CuN4 cuprous complexes interacting with O2, CO or CH3CN.

de la Lande A, Gérard H, Moliner V, Izzet G, Reinaud O, Parisel O.

J Biol Inorg Chem. 2006 Jul;11(5):593-608. Epub 2006 May 17.

PMID:
16791643
[PubMed - indexed for MEDLINE]
18.

Isocyanide binding to the copper(I) centers of the catalytic core of peptidylglycine monooxygenase (PHMcc).

Rhames FC, Murthy NN, Karlin KD, Blackburn NJ.

J Biol Inorg Chem. 2001 Jun;6(5-6):567-77.

PMID:
11472020
[PubMed - indexed for MEDLINE]
19.

Structural investigations on the coordination environment of the active-site copper centers of recombinant bifunctional peptidylglycine alpha-amidating enzyme.

Boswell JS, Reedy BJ, Kulathila R, Merkler D, Blackburn NJ.

Biochemistry. 1996 Sep 24;35(38):12241-50.

PMID:
8823157
[PubMed - indexed for MEDLINE]
20.

The catalytic mechanism of peptidylglycine alpha-hydroxylating monooxygenase investigated by computer simulation.

Crespo A, Martí MA, Roitberg AE, Amzel LM, Estrin DA.

J Am Chem Soc. 2006 Oct 4;128(39):12817-28.

PMID:
17002377
[PubMed - indexed for MEDLINE]

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