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Results: 1 to 20 of 123

1.

PHOX2B-mediated regulation of ALK expression: in vitro identification of a functional relationship between two genes involved in neuroblastoma.

Bachetti T, Di Paolo D, Di Lascio S, Mirisola V, Brignole C, Bellotti M, Caffa I, Ferraris C, Fiore M, Fornasari D, Chiarle R, Borghini S, Pfeffer U, Ponzoni M, Ceccherini I, Perri P.

PLoS One. 2010 Oct 1;5(10). pii: e13108. doi: 10.1371/journal.pone.0013108.

PMID:
20957039
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

PHOX2A and PHOX2B genes are highly co-expressed in human neuroblastoma.

Longo L, Borghini S, Schena F, Parodi S, Albino D, Bachetti T, Da Prato L, Truini M, Gambini C, Tonini GP, Ceccherini I, Perri P.

Int J Oncol. 2008 Nov;33(5):985-91.

PMID:
18949361
[PubMed - indexed for MEDLINE]
3.

Methylation-associated PHOX2B gene silencing is a rare event in human neuroblastoma.

de Pontual L, Trochet D, Bourdeaut F, Thomas S, Etchevers H, Chompret A, Minard V, Valteau D, Brugieres L, Munnich A, Delattre O, Lyonnet S, Janoueix-Lerosey I, Amiel J.

Eur J Cancer. 2007 Nov;43(16):2366-72. Epub 2007 Aug 31.

PMID:
17765533
[PubMed - indexed for MEDLINE]
4.
5.

PHOX2B mutations and genetic predisposition to neuroblastoma.

Perri P, Bachetti T, Longo L, Matera I, Seri M, Tonini GP, Ceccherini I.

Oncogene. 2005 Apr 21;24(18):3050-3.

PMID:
15735672
[PubMed - indexed for MEDLINE]
6.

Germline mutations of the paired-like homeobox 2B (PHOX2B) gene in neuroblastoma.

Trochet D, Bourdeaut F, Janoueix-Lerosey I, Deville A, de Pontual L, Schleiermacher G, Coze C, Philip N, Frébourg T, Munnich A, Lyonnet S, Delattre O, Amiel J.

Am J Hum Genet. 2004 Apr;74(4):761-4. Epub 2004 Mar 11.

PMID:
15024693
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Autonomic neurocristopathy-associated mutations in PHOX2B dysregulate Sox10 expression.

Nagashimada M, Ohta H, Li C, Nakao K, Uesaka T, Brunet JF, Amiel J, Trochet D, Wakayama T, Enomoto H.

J Clin Invest. 2012 Sep 4;122(9):3145-58. doi: 10.1172/JCI63401. Epub 2012 Aug 27.

PMID:
22922260
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Prevalence and functional consequence of PHOX2B mutations in neuroblastoma.

Raabe EH, Laudenslager M, Winter C, Wasserman N, Cole K, LaQuaglia M, Maris DJ, Mosse YP, Maris JM.

Oncogene. 2008 Jan 17;27(4):469-76. Epub 2007 Jul 16.

PMID:
17637745
[PubMed - indexed for MEDLINE]
9.

Neuroblastoma phox2b variants stimulate proliferation and dedifferentiation of immature sympathetic neurons.

Reiff T, Tsarovina K, Majdazari A, Schmidt M, del Pino I, Rohrer H.

J Neurosci. 2010 Jan 20;30(3):905-15. doi: 10.1523/JNEUROSCI.5368-09.2010.

PMID:
20089899
[PubMed - indexed for MEDLINE]
Free Article
10.

Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma.

Janoueix-Lerosey I, Lequin D, Brugières L, Ribeiro A, de Pontual L, Combaret V, Raynal V, Puisieux A, Schleiermacher G, Pierron G, Valteau-Couanet D, Frebourg T, Michon J, Lyonnet S, Amiel J, Delattre O.

Nature. 2008 Oct 16;455(7215):967-70. doi: 10.1038/nature07398.

PMID:
18923523
[PubMed - indexed for MEDLINE]
11.

Sp proteins and Phox2b regulate the expression of the human Phox2a gene.

Flora A, Lucchetti H, Benfante R, Goridis C, Clementi F, Fornasari D.

J Neurosci. 2001 Sep 15;21(18):7037-45.

PMID:
11549713
[PubMed - indexed for MEDLINE]
Free Article
12.

Selective therapeutic targeting of the anaplastic lymphoma kinase with liposomal siRNA induces apoptosis and inhibits angiogenesis in neuroblastoma.

Di Paolo D, Ambrogio C, Pastorino F, Brignole C, Martinengo C, Carosio R, Loi M, Pagnan G, Emionite L, Cilli M, Ribatti D, Allen TM, Chiarle R, Ponzoni M, Perri P.

Mol Ther. 2011 Dec;19(12):2201-12. doi: 10.1038/mt.2011.142. Epub 2011 Aug 9.

PMID:
21829174
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Effects of transcription factors Phox2 on expression of norepinephrine transporter and dopamine beta-hydroxylase in SK-N-BE(2)C cells.

Fan Y, Huang J, Kieran N, Zhu MY.

J Neurochem. 2009 Sep;110(5):1502-13. doi: 10.1111/j.1471-4159.2009.06260.x. Epub 2009 Jul 1.

PMID:
19573018
[PubMed - indexed for MEDLINE]
14.

Inhibition of N-linked glycosylation impairs ALK phosphorylation and disrupts pro-survival signaling in neuroblastoma cell lines.

Del Grosso F, De Mariano M, Passoni L, Luksch R, Tonini GP, Longo L.

BMC Cancer. 2011 Dec 22;11:525. doi: 10.1186/1471-2407-11-525.

PMID:
22192458
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Paired-like homeodomain proteins, Phox2a and Phox2b, are responsible for noradrenergic cell-specific transcription of the dopamine beta-hydroxylase gene.

Yang C, Kim HS, Seo H, Kim CH, Brunet JF, Kim KS.

J Neurochem. 1998 Nov;71(5):1813-26.

PMID:
9798905
[PubMed - indexed for MEDLINE]
16.

PHOX2B analysis in non-syndromic neuroblastoma cases shows novel mutations and genotype-phenotype associations.

McConville C, Reid S, Baskcomb L, Douglas J, Rahman N.

Am J Med Genet A. 2006 Jun 15;140(12):1297-301.

PMID:
16691592
[PubMed - indexed for MEDLINE]
17.

Molecular pathogenesis of peripheral neuroblastic tumors.

Janoueix-Lerosey I, Schleiermacher G, Delattre O.

Oncogene. 2010 Mar 18;29(11):1566-79. doi: 10.1038/onc.2009.518. Epub 2010 Jan 25. Review.

PMID:
20101209
[PubMed - indexed for MEDLINE]
18.

Anaplastic Lymphoma Kinase (ALK) regulates initiation of transcription of MYCN in neuroblastoma cells.

Schönherr C, Ruuth K, Kamaraj S, Wang CL, Yang HL, Combaret V, Djos A, Martinsson T, Christensen JG, Palmer RH, Hallberg B.

Oncogene. 2012 Dec 13;31(50):5193-200. doi: 10.1038/onc.2012.12. Epub 2012 Jan 30.

PMID:
22286764
[PubMed - indexed for MEDLINE]
19.

Germline mutations of the paired-like homeobox 2B (PHOX2B) gene in neuroblastoma.

Bourdeaut F, Trochet D, Janoueix-Lerosey I, Ribeiro A, Deville A, Coz C, Michiels JF, Lyonnet S, Amiel J, Delattre O.

Cancer Lett. 2005 Oct 18;228(1-2):51-8. Review.

PMID:
15949893
[PubMed - indexed for MEDLINE]
20.

PHOX2B regulates its own expression by a transcriptional auto-regulatory mechanism.

Cargnin F, Flora A, Di Lascio S, Battaglioli E, Longhi R, Clementi F, Fornasari D.

J Biol Chem. 2005 Nov 11;280(45):37439-48. Epub 2005 Sep 6.

PMID:
16144830
[PubMed - indexed for MEDLINE]
Free Article

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