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Results: 1 to 20 of 81

1.

The Rab11a GTPase controls Toll-like receptor 4-induced activation of interferon regulatory factor-3 on phagosomes.

Husebye H, Aune MH, Stenvik J, Samstad E, Skjeldal F, Halaas O, Nilsen NJ, Stenmark H, Latz E, Lien E, Mollnes TE, Bakke O, Espevik T.

Immunity. 2010 Oct 29;33(4):583-96. doi: 10.1016/j.immuni.2010.09.010. Epub 2010 Oct 7.

PMID:
20933442
[PubMed - indexed for MEDLINE]
Free Article
2.

The small GTPase Arf6 is essential for the Tram/Trif pathway in TLR4 signaling.

Van Acker T, Eyckerman S, Vande Walle L, Gerlo S, Goethals M, Lamkanfi M, Bovijn C, Tavernier J, Peelman F.

J Biol Chem. 2014 Jan 17;289(3):1364-76. doi: 10.1074/jbc.M113.499194. Epub 2013 Dec 2.

PMID:
24297182
[PubMed - indexed for MEDLINE]
3.

Phospholipase Cγ-2 and intracellular calcium are required for lipopolysaccharide-induced Toll-like receptor 4 (TLR4) endocytosis and interferon regulatory factor 3 (IRF3) activation.

Chiang CY, Veckman V, Limmer K, David M.

J Biol Chem. 2012 Feb 3;287(6):3704-9. doi: 10.1074/jbc.C111.328559. Epub 2011 Dec 12.

PMID:
22158869
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Lysosome-associated small Rab GTPase Rab7b negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4.

Wang Y, Chen T, Han C, He D, Liu H, An H, Cai Z, Cao X.

Blood. 2007 Aug 1;110(3):962-71. Epub 2007 Mar 29.

PMID:
17395780
[PubMed - indexed for MEDLINE]
Free Article
5.

Induction of in vitro reprogramming by Toll-like receptor (TLR)2 and TLR4 agonists in murine macrophages: effects of TLR "homotolerance" versus "heterotolerance" on NF-kappa B signaling pathway components.

Dobrovolskaia MA, Medvedev AE, Thomas KE, Cuesta N, Toshchakov V, Ren T, Cody MJ, Michalek SM, Rice NR, Vogel SN.

J Immunol. 2003 Jan 1;170(1):508-19.

PMID:
12496438
[PubMed - indexed for MEDLINE]
Free Article
6.

Involvement of TNFα-induced TLR4-NF-κB and TLR4-HIF-1α feed-forward loops in the regulation of inflammatory responses in glioma.

Tewari R, Choudhury SR, Ghosh S, Mehta VS, Sen E.

J Mol Med (Berl). 2012 Jan;90(1):67-80. doi: 10.1007/s00109-011-0807-6. Epub 2011 Sep 2.

PMID:
21887505
[PubMed - indexed for MEDLINE]
7.

TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88-independent TLR4 pathway.

Palsson-McDermott EM, Doyle SL, McGettrick AF, Hardy M, Husebye H, Banahan K, Gong M, Golenbock D, Espevik T, O'Neill LA.

Nat Immunol. 2009 Jun;10(6):579-86. doi: 10.1038/ni.1727. Epub 2009 May 3.

PMID:
19412184
[PubMed - indexed for MEDLINE]
8.

TAK-242 (resatorvid), a small-molecule inhibitor of Toll-like receptor (TLR) 4 signaling, binds selectively to TLR4 and interferes with interactions between TLR4 and its adaptor molecules.

Matsunaga N, Tsuchimori N, Matsumoto T, Ii M.

Mol Pharmacol. 2011 Jan;79(1):34-41. doi: 10.1124/mol.110.068064. Epub 2010 Sep 29.

PMID:
20881006
[PubMed - indexed for MEDLINE]
Free Article
9.

Acrolein with an alpha, beta-unsaturated carbonyl group inhibits LPS-induced homodimerization of toll-like receptor 4.

Lee JS, Lee JY, Lee MY, Hwang DH, Youn HS.

Mol Cells. 2008 Apr 30;25(2):253-7. Epub 2008 Mar 31.

PMID:
18414004
[PubMed - indexed for MEDLINE]
Free Article
10.

The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling.

Schoenemeyer A, Barnes BJ, Mancl ME, Latz E, Goutagny N, Pitha PM, Fitzgerald KA, Golenbock DT.

J Biol Chem. 2005 Apr 29;280(17):17005-12. Epub 2005 Jan 28.

PMID:
15695821
[PubMed - indexed for MEDLINE]
Free Article
11.

C-reactive protein triggers inflammatory responses partly via TLR4/IRF3/NF-κB signaling pathway in rat vascular smooth muscle cells.

Liu N, Liu JT, Ji YY, Lu PP.

Life Sci. 2010 Sep 11;87(11-12):367-74. doi: 10.1016/j.lfs.2010.07.012. Epub 2010 Aug 4.

PMID:
20670634
[PubMed - indexed for MEDLINE]
12.

Inhibition of phosphoinositide 3-kinase enhances TRIF-dependent NF-kappa B activation and IFN-beta synthesis downstream of Toll-like receptor 3 and 4.

Aksoy E, Vanden Berghe W, Detienne S, Amraoui Z, Fitzgerald KA, Haegeman G, Goldman M, Willems F.

Eur J Immunol. 2005 Jul;35(7):2200-9.

PMID:
15940673
[PubMed - indexed for MEDLINE]
13.

Bovine TLR2 and TLR4 properly transduce signals from Staphylococcus aureus and E. coli, but S. aureus fails to both activate NF-kappaB in mammary epithelial cells and to quickly induce TNFalpha and interleukin-8 (CXCL8) expression in the udder.

Yang W, Zerbe H, Petzl W, Brunner RM, Günther J, Draing C, von Aulock S, Schuberth HJ, Seyfert HM.

Mol Immunol. 2008 Mar;45(5):1385-97. Epub 2007 Oct 22.

PMID:
17936907
[PubMed - indexed for MEDLINE]
14.

Inhibitory effect of Toll-like receptor 4 on fusion between phagosomes and endosomes/lysosomes in macrophages.

Shiratsuchi A, Watanabe I, Takeuchi O, Akira S, Nakanishi Y.

J Immunol. 2004 Feb 15;172(4):2039-47.

PMID:
14764668
[PubMed - indexed for MEDLINE]
Free Article
15.

Suppression of MyD88- and TRIF-dependent signaling pathways of Toll-like receptor by (-)-epigallocatechin-3-gallate, a polyphenol component of green tea.

Youn HS, Lee JY, Saitoh SI, Miyake K, Kang KW, Choi YJ, Hwang DH.

Biochem Pharmacol. 2006 Sep 28;72(7):850-9. Epub 2006 Aug 4.

PMID:
16890209
[PubMed - indexed for MEDLINE]
16.

Selenium suppresses the activation of transcription factor NF-kappa B and IRF3 induced by TLR3 or TLR4 agonists.

Youn HS, Lim HJ, Choi YJ, Lee JY, Lee MY, Ryu JH.

Int Immunopharmacol. 2008 Mar;8(3):495-501. doi: 10.1016/j.intimp.2007.12.008. Epub 2008 Jan 14.

PMID:
18279804
[PubMed - indexed for MEDLINE]
17.

Inhibition of homodimerization of Toll-like receptor 4 by curcumin.

Youn HS, Saitoh SI, Miyake K, Hwang DH.

Biochem Pharmacol. 2006 Jun 28;72(1):62-9. Epub 2006 Apr 1.

PMID:
16678799
[PubMed - indexed for MEDLINE]
18.

Enterocyte TLR4 mediates phagocytosis and translocation of bacteria across the intestinal barrier.

Neal MD, Leaphart C, Levy R, Prince J, Billiar TR, Watkins S, Li J, Cetin S, Ford H, Schreiber A, Hackam DJ.

J Immunol. 2006 Mar 1;176(5):3070-9.

PMID:
16493066
[PubMed - indexed for MEDLINE]
Free Article
19.

TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to toll-like receptor 4 TICAM-1 that induces interferon-beta.

Oshiumi H, Sasai M, Shida K, Fujita T, Matsumoto M, Seya T.

J Biol Chem. 2003 Dec 12;278(50):49751-62. Epub 2003 Sep 30.

PMID:
14519765
[PubMed - indexed for MEDLINE]
Free Article
20.

Toll-like receptor 4 plays a role in macrophage phagocytosis during peritoneal sepsis.

Anand RJ, Kohler JW, Cavallo JA, Li J, Dubowski T, Hackam DJ.

J Pediatr Surg. 2007 Jun;42(6):927-32; discussion 933.

PMID:
17560196
[PubMed - indexed for MEDLINE]

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