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Results: 1 to 20 of 116

1.

Characterization of the xenobiotic response of Caenorhabditis elegans to the anthelmintic drug albendazole and the identification of novel drug glucoside metabolites.

Laing ST, Ivens A, Laing R, Ravikumar S, Butler V, Woods DJ, Gilleard JS.

Biochem J. 2010 Dec 15;432(3):505-14. doi: 10.1042/BJ20101346.

PMID:
20929438
[PubMed - indexed for MEDLINE]
Free Article
2.

Biotransformation of albendazole and activities of selected detoxification enzymes in Haemonchus contortus strains susceptible and resistant to anthelmintics.

Vokřál I, Jirásko R, Stuchlíková L, Bártíková H, Szotáková B, Lamka J, Várady M, Skálová L.

Vet Parasitol. 2013 Sep 23;196(3-4):373-81. doi: 10.1016/j.vetpar.2013.03.018. Epub 2013 Mar 26.

PMID:
23587403
[PubMed - indexed for MEDLINE]
3.

Dose-dependent activity of albendazole against benzimidazole-resistant nematodes in sheep: relationship between pharmacokinetics and efficacy.

Moreno L, Echevarria F, Muñoz F, Alvarez L, Sanchez Bruni S, Lanusse C.

Exp Parasitol. 2004 Mar-Apr;106(3-4):150-7.

PMID:
15172222
[PubMed - indexed for MEDLINE]
4.

Anthelmintic activity of KSI-4088 against Caenorhabditis elegans.

Kaewintajuk K, Cho PY, Kim SY, Lee ES, Lee HK, Choi EB, Park H.

Parasitol Res. 2010 Jun;107(1):27-30. doi: 10.1007/s00436-010-1828-8. Epub 2010 Mar 23.

PMID:
20309581
[PubMed - indexed for MEDLINE]
5.

Unique structure and regulation of the nematode detoxification gene regulator, SKN-1: implications to understanding and controlling drug resistance.

Choe KP, Leung CK, Miyamoto MM.

Drug Metab Rev. 2012 Aug;44(3):209-23. doi: 10.3109/03602532.2012.684799. Epub 2012 Jun 4. Review.

PMID:
22656429
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Beta-tubulin genes from the parasitic nematode Haemonchus contortus modulate drug resistance in Caenorhabditis elegans.

Kwa MS, Veenstra JG, Van Dijk M, Roos MH.

J Mol Biol. 1995 Mar 3;246(4):500-10.

PMID:
7877171
[PubMed - indexed for MEDLINE]
7.

A new class of anthelmintics effective against drug-resistant nematodes.

Kaminsky R, Ducray P, Jung M, Clover R, Rufener L, Bouvier J, Weber SS, Wenger A, Wieland-Berghausen S, Goebel T, Gauvry N, Pautrat F, Skripsky T, Froelich O, Komoin-Oka C, Westlund B, Sluder A, Mäser P.

Nature. 2008 Mar 13;452(7184):176-80. doi: 10.1038/nature06722.

PMID:
18337814
[PubMed - indexed for MEDLINE]
8.

A comparison of the effects of ivermectin and moxidectin on the nematode Caenorhabditis elegans.

Ardelli BF, Stitt LE, Tompkins JB, Prichard RK.

Vet Parasitol. 2009 Oct 28;165(1-2):96-108. doi: 10.1016/j.vetpar.2009.06.043. Epub 2009 Jul 8.

PMID:
19631471
[PubMed - indexed for MEDLINE]
9.

Adaptive and specialised transcriptional responses to xenobiotic stress in Caenorhabditis elegans are regulated by nuclear hormone receptors.

Jones LM, Rayson SJ, Flemming AJ, Urwin PE.

PLoS One. 2013 Jul 26;8(7):e69956. doi: 10.1371/journal.pone.0069956. Print 2013.

PMID:
23922869
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Xenobiotic metabolizing enzymes and metabolism of anthelminthics in helminths.

Cvilink V, Lamka J, Skálová L.

Drug Metab Rev. 2009;41(1):8-26. doi: 10.1080/03602530802602880. Review.

PMID:
19514969
[PubMed - indexed for MEDLINE]
11.

SLO-1-channels of parasitic nematodes reconstitute locomotor behaviour and emodepside sensitivity in Caenorhabditis elegans slo-1 loss of function mutants.

Welz C, Krüger N, Schniederjans M, Miltsch SM, Krücken J, Guest M, Holden-Dye L, Harder A, von Samson-Himmelstjerna G.

PLoS Pathog. 2011 Apr;7(4):e1001330. doi: 10.1371/journal.ppat.1001330. Epub 2011 Apr 7.

PMID:
21490955
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Toxic effects of di(2-ethylhexyl)phthalate on mortality, growth, reproduction and stress-related gene expression in the soil nematode Caenorhabditis elegans.

Roh JY, Jung IH, Lee JY, Choi J.

Toxicology. 2007 Jul 31;237(1-3):126-33. Epub 2007 May 18.

PMID:
17604895
[PubMed - indexed for MEDLINE]
13.

Activity of novel nicotinic anthelmintics in cut preparations of Caenorhabditis elegans.

Ruiz-Lancheros E, Viau C, Walter TN, Francis A, Geary TG.

Int J Parasitol. 2011 Mar;41(3-4):455-61. doi: 10.1016/j.ijpara.2010.11.009. Epub 2010 Dec 30.

PMID:
21195075
[PubMed - indexed for MEDLINE]
14.

Caenorhabditis elegans as a model for the screening of anthelminthic compounds: ultrastructural study of the effects of albendazole.

Sant'anna V, Vommaro RC, de Souza W.

Exp Parasitol. 2013 Sep;135(1):1-8. doi: 10.1016/j.exppara.2013.05.011. Epub 2013 May 29.

PMID:
23727123
[PubMed - indexed for MEDLINE]
Free Article
15.

Effect of benzimidazole drugs on tubulin in benzimidazole resistant and susceptible strains of Caenorhabditis elegans.

Enos A, Coles GC.

Int J Parasitol. 1990 Apr;20(2):161-7.

PMID:
2332276
[PubMed - indexed for MEDLINE]
16.

Anthelmintic drugs.

Holden-Dye L, Walker RJ.

WormBook. 2007 Nov 2:1-13. Review.

PMID:
17988075
[PubMed - indexed for MEDLINE]
Free Article
17.

The activity of drug-metabolizing enzymes and the biotransformation of selected anthelmintics in the model tapeworm Hymenolepis diminuta.

Bártíková H, Vokřál I, Skálová L, Kubíček V, Firbasová J, Briestenský D, Lamka J, Szotáková B.

Parasitology. 2012 May;139(6):809-18. doi: 10.1017/S0031182011002265. Epub 2012 Feb 6.

PMID:
22309895
[PubMed - indexed for MEDLINE]
18.

LC-MS-MS identification of albendazole and flubendazole metabolites formed ex vivo by Haemonchus contortus.

Cvilink V, Skálová L, Szotáková B, Lamka J, Kostiainen R, Ketola RA.

Anal Bioanal Chem. 2008 May;391(1):337-43. doi: 10.1007/s00216-008-1863-9. Epub 2008 Mar 17.

PMID:
18344069
[PubMed - indexed for MEDLINE]
19.

Albendazole repeated administration induces cytochromes P4501A and accelerates albendazole deactivation in mouflon (Ovis musimon).

Velík J, Szotáková B, Baliharová V, Lamka J, Savlík M, Wsól V, Snejdrová E, Skálová L.

Res Vet Sci. 2005 Jun;78(3):255-63.

PMID:
15766946
[PubMed - indexed for MEDLINE]
20.

Inhibitory effect of albendazole and its metabolites on cytochromes P450 activities in rat and mouflon in vitro.

Baliharová V, Velík J, Fimanová K, Lamka J, Szotáková B, Savlík M, Skálová L.

Pharmacol Rep. 2005 Jan-Feb;57(1):97-106.

PMID:
15849383
[PubMed - indexed for MEDLINE]
Free Article

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