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Results: 1 to 20 of 127

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1.

Effects of a defective ERAD pathway on growth and heterologous protein production in Aspergillus niger.

Carvalho ND, Arentshorst M, Kooistra R, Stam H, Sagt CM, van den Hondel CA, Ram AF.

Appl Microbiol Biotechnol. 2011 Jan;89(2):357-73. doi: 10.1007/s00253-010-2916-5. Epub 2010 Oct 5.

2.

Endoplasmic reticulum stress leads to the selective transcriptional downregulation of the glucoamylase gene in Aspergillus niger.

Al-Sheikh H, Watson AJ, Lacey GA, Punt PJ, MacKenzie DA, Jeenes DJ, Pakula T, Penttilä M, Alcocer MJ, Archer DB.

Mol Microbiol. 2004 Sep;53(6):1731-42.

PMID:
15341651
3.

The virulence of the opportunistic fungal pathogen Aspergillus fumigatus requires cooperation between the endoplasmic reticulum-associated degradation pathway (ERAD) and the unfolded protein response (UPR).

Richie DL, Feng X, Hartl L, Aimanianda V, Krishnan K, Powers-Fletcher MV, Watson DS, Galande AK, White SM, Willett T, Latgé JP, Rhodes JC, Askew DS.

Virulence. 2011 Jan-Feb;2(1):12-21. Epub 2011 Jan 1.

4.

The transcriptomic fingerprint of glucoamylase over-expression in Aspergillus niger.

Kwon MJ, Jørgensen TR, Nitsche BM, Arentshorst M, Park J, Ram AF, Meyer V.

BMC Genomics. 2012 Dec 13;13:701. doi: 10.1186/1471-2164-13-701.

5.

Effects of a defective endoplasmic reticulum-associated degradation pathway on the stress response, virulence, and antifungal drug susceptibility of the mold pathogen Aspergillus fumigatus.

Krishnan K, Feng X, Powers-Fletcher MV, Bick G, Richie DL, Woollett LA, Askew DS.

Eukaryot Cell. 2013 Apr;12(4):512-9. doi: 10.1128/EC.00319-12. Epub 2013 Jan 25.

6.

Effective lead selection for improved protein production in Aspergillus niger based on integrated genomics.

Jacobs DI, Olsthoorn MM, Maillet I, Akeroyd M, Breestraat S, Donkers S, van der Hoeven RA, van den Hondel CA, Kooistra R, Lapointe T, Menke H, Meulenberg R, Misset M, Müller WH, van Peij NN, Ram A, Rodriguez S, Roelofs MS, Roubos JA, van Tilborg MW, Verkleij AJ, Pel HJ, Stam H, Sagt CM.

Fungal Genet Biol. 2009 Mar;46 Suppl 1:S141-52. doi: 10.1016/j.fgb.2008.08.012. Epub 2008 Sep 12.

PMID:
18824119
7.

Characterization of a foldase, protein disulfide isomerase A, in the protein secretory pathway of Aspergillus niger.

Ngiam C, Jeenes DJ, Punt PJ, Van Den Hondel CA, Archer DB.

Appl Environ Microbiol. 2000 Feb;66(2):775-82.

8.

Analysis of the role of the gene bipA, encoding the major endoplasmic reticulum chaperone protein in the secretion of homologous and heterologous proteins in black Aspergilli.

Punt PJ, van Gemeren IA, Drint-Kuijvenhoven J, Hessing JG, van Muijlwijk-Harteveld GM, Beijersbergen A, Verrips CT, van den Hondel CA.

Appl Microbiol Biotechnol. 1998 Oct;50(4):447-54.

PMID:
9830095
9.

Transcriptomic comparison of Aspergillus niger growing on two different sugars reveals coordinated regulation of the secretory pathway.

Jørgensen TR, Goosen T, Hondel CA, Ram AF, Iversen JJ.

BMC Genomics. 2009 Jan 23;10:44. doi: 10.1186/1471-2164-10-44.

10.

Genomic analysis of the secretion stress response in the enzyme-producing cell factory Aspergillus niger.

Guillemette T, van Peij N, Goosen T, Lanthaler K, Robson GD, van den Hondel CA, Stam H, Archer DB.

BMC Genomics. 2007 Jun 11;8:158.

11.

The Aspergillus niger annexin, anxC3.1 is constitutively expressed and is not essential for protein secretion.

Khalaj V, Hey P, Smith L, Robson GD, Brookman J.

FEMS Microbiol Lett. 2004 Oct 1;239(1):163-9.

12.

Improvement of foreign-protein production in Aspergillus niger var. awamori by constitutive induction of the unfolded-protein response.

Valkonen M, Ward M, Wang H, Penttilä M, Saloheimo M.

Appl Environ Microbiol. 2003 Dec;69(12):6979-86.

13.

Methods for investigating the UPR in filamentous fungi.

Guillemette T, Ram AF, Carvalho ND, Joubert A, Simoneau P, Archer DB.

Methods Enzymol. 2011;490:1-29. doi: 10.1016/B978-0-12-385114-7.00001-5.

PMID:
21266241
14.

Isolation and characterisation of a calnexin homologue, clxA, from Aspergillus niger.

Wang H, Entwistle J, Morlon E, Archer DB, Peberdy JF, Ward M, Jeenes DJ.

Mol Genet Genomics. 2003 Feb;268(5):684-91. Epub 2003 Jan 15.

PMID:
12589443
15.

HacA-independent induction of chaperone-encoding gene bipA in Aspergillus niger strains overproducing membrane proteins.

Davé A, Jeenes DJ, Mackenzie DA, Archer DB.

Appl Environ Microbiol. 2006 Jan;72(1):953-5.

16.

Shotgun proteomics of Aspergillus niger microsomes upon D-xylose induction.

Ferreira de Oliveira JM, van Passel MW, Schaap PJ, de Graaff LH.

Appl Environ Microbiol. 2010 Jul;76(13):4421-9. doi: 10.1128/AEM.00482-10. Epub 2010 May 7.

17.

Mif1: a missing link between the unfolded protein response pathway and ER-associated protein degradation?

van Laar T, van der Eb AJ, Terleth C.

Curr Protein Pept Sci. 2001 Jun;2(2):169-90. Review.

PMID:
12370023
18.

Recombinant hepatitis B surface antigen production in Aspergillus niger: evaluating the strategy of gene fusion to native glucoamylase.

James E, van Zyl W, van Zyl P, Görgens J.

Appl Microbiol Biotechnol. 2012 Oct;96(2):385-94. doi: 10.1007/s00253-012-4191-0. Epub 2012 Jun 13.

PMID:
22688905
19.

Phylogeny of fungal hemoglobins and expression analysis of the Aspergillus oryzae flavohemoglobin gene fhbA during hyphal growth.

te Biesebeke R, Levasseur A, Boussier A, Record E, van den Hondel CA, Punt PJ.

Fungal Biol. 2010 Feb-Mar;114(2-3):135-43.

PMID:
20960969
20.

Molecular genetic analysis of vesicular transport in Aspergillus niger reveals partial conservation of the molecular mechanism of exocytosis in fungi.

Kwon MJ, Arentshorst M, Fiedler M, de Groen FL, Punt PJ, Meyer V, Ram AF.

Microbiology. 2014 Feb;160(Pt 2):316-29. doi: 10.1099/mic.0.074252-0. Epub 2013 Dec 2.

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