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20888885,16781459,23042187,26852687,16214041,15024026,26291957,28286125,21658364,27826077,18511885,19174156,22246431,24719331,21236252,24795232,17196236,14731112,14980980,21083424,18634870,20822529,17644290,12112002,29258000,19833168,18435907,16480975,19169644,18291107,20088848,28213287,20656003,11875494,22769443,16765938,22488045,21975817,25744452,14563492,15316927,18357586,22119385,10872747,20833156,20430097,25091623,23747519,29883945,23333393,26388191,17532486,28351780,18325727,22683523,16329999,23178030,27523796,12947311,17631927,18929556,21457761,16289764,16457781,20940016,33343802,22369644,18258363,18022235,19497418,23775080,28791341,28250268,23859871,15833736,10925299,23360889,24291486,23298677,24366007,20969575,22353229,23022510,28350760,20954800,23357604,21843620,23124098,25615876,23395777,18768868,23969109,28782507,26778276,24029593,28302174,25239868,29311246,21963524,25605059,25638774,21174079,15220209,27770660,12376363,22743041,27412767,22137262,29309760,22720096,25463280,31505119,36517023,28882947,22160840,22159604,16631521,21192278,15557194,18541231,24401606,28259922,27070586,20954072,16439612,17560646,22442118,15337692,25692285,11901050,23021350,17349851,28770019,30302660,27598576,26163453,24846829,36437552,31261663,23861314,27113811,21238556,19131585,27921103,26163808,26200092,21321939,29165873,22766494,26849905,14523007,14651954,25593217,29475907,26597893,24530569,31861488,29669713,28378774,20336709,25133186,25341814,19845678,35007301,23199195,20568122,24406683,16533596,14732289,23294286,22166397,24337631,24415199,16888021,16710743,16951197,30425781,16394696,21437926,16456000,18434445,26286380,21564546,25169430,24972270,33804125,21865167,20643109,21889036,31882466,20442693,22928017,20708206,16565722,29309766,21307647,25448262,27693692,12225729,26796539,27582555,23717538,21414301,24839356,16476785,32121307,19578789,24361407,26481132,16970244,30593539,19098111,22147556,23707273,26492285,25932745,23010497,15770161,26876575,11140691,27644075,22564156,30794693,15699165,30594624,21131421,27451975,30782300,21040116,22212320,30068325,24722370,24053326,35286219,17115070,29656184,17495224,25471815,24140437,26993595,27721085,18574454,22004613,30333287,25815437,19764090,20940037,26672618,25091807,11287117,15653758,23425954,18323531,20709802,24185179,29546728,16943204,27832635,12832044,11165873,23052192,16319092,23290930,23606537,31677062,22841776,23285267,11134661,35453467,19227148,27222046,22158875,12194971,18354228,16798746,9434639,31659617,17091190,24086554,20579867,25462643,11704975,29574654,20348015,25475530,23307413,19414066,11032845,11498451,19534727,27052497,18596041,18289074,30092496,28874754,22543247,25652735,29300456,25343247,30213580,9714807,28177671,24045154,29796178,27089465,21354100,26866925,29191728,21571064,21050989,24257033,18390757,23649692,25091622,16625420,27356576,20180005,12361722,16495208,15577133,25044064,15545282,23872397,28093607,15665518,36995736,20844928,33580696,21833623,9034242,31678866,21857083,29111167,20704547,32862202,24598415,23661026,27185013,32716106,9380023,23525626,20803131,11914132,24431404,16467537,27983949,25150395,17671894,30717437,25897920,21036202,31989470,8234347,22989377,28159595,26879317,20958960,20970835,22247601,32745467,16271489,9458000,23852498,19133325,27842943,17020887,24376630,34310076,21136273,28624264,29404326,30349652,7578935,27737527,28381769,34951183,26205966,22844479,28723418,25686497,25223958,25762501,33066585,15361524,29449858,30246411,34206530,31636810,23164715,23543651,22330859,31816826,34063678,36429198,21669191,29869624,12403350,19404720,28983907,18096048,18417643,24797940,28003814,36539019,33514947,25738463,33398364,23726240,28804558,32054389,11754687,32363436,2229007,22138245,24862327,33333908,33912151,25902355,32188144,26795112,31540482,30014797,11872191,12901910,34415167,19371603,24147608,28113127,19885007,18274635,24961479,10098655,27642560,29466449,20104260,21860593,10475089,35954269,10571526,29940728,12749898,31231394,18701497,29920184,9693301,35260900,8562440,29194351,9314602,29731430,17982876,8937419,21975295,20481554,35613428,26413252,23513850,31029180,23639002,31150038,26014120,29163759,28970779,32556674,29075208,8812640,32652335,35510392[uid]

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The inhibitory effect of raloxifene on lipopolysaccharide-induced nitric oxide production in RAW264.7 cells is mediated through a ROS/p38 MAPK/CREB pathway to the up-regulation of heme oxygenase-1 independent of estrogen receptor.

Lee SA, Kim EY, Jeon WK, Woo CH, Choe J, Han S, Kim BC. Lee SA, et al. Biochimie. 2011 Feb;93(2):168-74. doi: 10.1016/j.biochi.2010.09.007. Epub 2010 Oct 1. Biochimie. 2011. PMID: 20888885

Hydrogen sulfide inhibits nitric oxide production and nuclear factor-kappaB via heme oxygenase-1 expression in RAW264.7 macrophages stimulated with lipopolysaccharide.

Oh GS, Pae HO, Lee BS, Kim BN, Kim JM, Kim HR, Jeon SB, Jeon WK, Chae HJ, Chung HT. Oh GS, et al. Free Radic Biol Med. 2006 Jul 1;41(1):106-19. doi: 10.1016/j.freeradbiomed.2006.03.021. Epub 2006 Apr 25. Free Radic Biol Med. 2006. PMID: 16781459

Prostaglandins as negative regulators against lipopolysaccharide, lipoteichoic acid, and peptidoglycan-induced inducible nitric oxide synthase/nitric oxide production through reactive oxygen species-dependent heme oxygenase 1 expression in macrophages.

Chien CC, Shen SC, Yang LY, Chen YC. Chien CC, et al. Shock. 2012 Nov;38(5):549-58. doi: 10.1097/SHK.0b013e31826b2826. Shock. 2012. PMID: 23042187

Amomum tsao-ko fruit extract suppresses lipopolysaccharide-induced inducible nitric oxide synthase by inducing heme oxygenase-1 in macrophages and in septic mice.

Shin JS, Ryu S, Jang DS, Cho YW, Chung EK, Lee KT. Shin JS, et al. Int J Exp Pathol. 2015 Dec;96(6):395-405. doi: 10.1111/iep.12159. Epub 2016 Jan 14. Int J Exp Pathol. 2015. PMID: 26852687 Free PMC article.

HMG-CoA reductase inhibitors upregulate heme oxygenase-1 expression in murine RAW264.7 macrophages via ERK, p38 MAPK and protein kinase G pathways.

Chen JC, Huang KC, Lin WW. Chen JC, et al. Cell Signal. 2006 Jan;18(1):32-9. doi: 10.1016/j.cellsig.2005.03.016. Epub 2005 Apr 20. Cell Signal. 2006. PMID: 16214041

15-deoxy-delta 12,14-prostaglandin J2 induces heme oxygenase-1 gene expression in a reactive oxygen species-dependent manner in human lymphocytes.

Alvarez-Maqueda M, El Bekay R, Alba G, Monteseirín J, Chacón P, Vega A, Martín-Nieto J, Bedoya FJ, Pintado E, Sobrino F. Alvarez-Maqueda M, et al. J Biol Chem. 2004 May 21;279(21):21929-37. doi: 10.1074/jbc.M400492200. Epub 2004 Mar 15. J Biol Chem. 2004. PMID: 15024026 Free article.

7-Methoxy-(9H-β-Carbolin-1-il)-(E)-1-Propenoic Acid, a β-Carboline Alkaloid From Eurycoma longifolia, Exhibits Anti-Inflammatory Effects by Activating the Nrf2/Heme Oxygenase-1 Pathway.

Nguyen HD, Choo YY, Nguyen TD, Nguyen HN, Chau VM, Lee JH. Nguyen HD, et al. J Cell Biochem. 2016 Mar;117(3):659-70. doi: 10.1002/jcb.25315. Epub 2015 Sep 3. J Cell Biochem. 2016. PMID: 26291957

n-Propyl gallate suppresses lipopolysaccharide-induced inducible nitric oxide synthase activation through protein kinase Cδ-mediated up-regulation of heme oxygenase-1 in RAW264.7 macrophages.

Jeon W, Park SJ, Kim BC. Jeon W, et al. Eur J Pharmacol. 2017 Apr 15;801:86-94. doi: 10.1016/j.ejphar.2017.03.005. Epub 2017 Mar 9. Eur J Pharmacol. 2017. PMID: 28286125

Genipin up-regulates heme oxygenase-1 via PI3-kinase-JNK1/2-Nrf2 signaling pathway to enhance the anti-inflammatory capacity in RAW264.7 macrophages.

Jeon WK, Hong HY, Kim BC. Jeon WK, et al. Arch Biochem Biophys. 2011 Aug 15;512(2):119-25. doi: 10.1016/j.abb.2011.05.016. Epub 2011 May 30. Arch Biochem Biophys. 2011. PMID: 21658364

Involvement of Nrf2-mediated heme oxygenase-1 expression in anti-inflammatory action of chitosan oligosaccharides through MAPK activation in murine macrophages.

Hyung JH, Ahn CB, Il Kim B, Kim K, Je JY. Hyung JH, et al. Eur J Pharmacol. 2016 Dec 15;793:43-48. doi: 10.1016/j.ejphar.2016.11.002. Epub 2016 Nov 6. Eur J Pharmacol. 2016. PMID: 27826077

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