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Results: 1 to 20 of 193

1.

What have we learned from Drosophila models of Parkinson's disease?

Guo M.

Prog Brain Res. 2010;184:3-16. doi: 10.1016/S0079-6123(10)84001-4. Review.

PMID:
20887867
[PubMed - indexed for MEDLINE]
2.

Drosophila as a model to study mitochondrial dysfunction in Parkinson's disease.

Guo M.

Cold Spring Harb Perspect Med. 2012 Nov 1;2(11). pii: a009944. doi: 10.1101/cshperspect.a009944. Review.

PMID:
23024178
[PubMed - indexed for MEDLINE]
3.

Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin.

Clark IE, Dodson MW, Jiang C, Cao JH, Huh JR, Seol JH, Yoo SJ, Hay BA, Guo M.

Nature. 2006 Jun 29;441(7097):1162-6. Epub 2006 May 3.

PMID:
16672981
[PubMed - indexed for MEDLINE]
4.

Parkinson's disease-associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondria.

Liu S, Sawada T, Lee S, Yu W, Silverio G, Alapatt P, Millan I, Shen A, Saxton W, Kanao T, Takahashi R, Hattori N, Imai Y, Lu B.

PLoS Genet. 2012;8(3):e1002537. doi: 10.1371/journal.pgen.1002537. Epub 2012 Mar 1.

PMID:
22396657
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Impaired mitochondrial dynamics and function in the pathogenesis of Parkinson's disease.

Büeler H.

Exp Neurol. 2009 Aug;218(2):235-46. doi: 10.1016/j.expneurol.2009.03.006. Epub 2009 Mar 18. Review.

PMID:
19303005
[PubMed - indexed for MEDLINE]
6.

The loss of PGAM5 suppresses the mitochondrial degeneration caused by inactivation of PINK1 in Drosophila.

Imai Y, Kanao T, Sawada T, Kobayashi Y, Moriwaki Y, Ishida Y, Takeda K, Ichijo H, Lu B, Takahashi R.

PLoS Genet. 2010 Dec 2;6(12):e1001229. doi: 10.1371/journal.pgen.1001229.

PMID:
21151955
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Mitochondrial dysfunction in genetic animal models of Parkinson's disease.

Trancikova A, Tsika E, Moore DJ.

Antioxid Redox Signal. 2012 May 1;16(9):896-919. doi: 10.1089/ars.2011.4200. Epub 2011 Oct 4. Review.

PMID:
21848447
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Loss-of-function analysis suggests that Omi/HtrA2 is not an essential component of the PINK1/PARKIN pathway in vivo.

Yun J, Cao JH, Dodson MW, Clark IE, Kapahi P, Chowdhury RB, Guo M.

J Neurosci. 2008 Dec 31;28(53):14500-10. doi: 10.1523/JNEUROSCI.5141-08.2008.

PMID:
19118185
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Pink1, Parkin, DJ-1 and mitochondrial dysfunction in Parkinson's disease.

Dodson MW, Guo M.

Curr Opin Neurobiol. 2007 Jun;17(3):331-7. Epub 2007 May 11. Review.

PMID:
17499497
[PubMed - indexed for MEDLINE]
10.

Mitochondrial dysfunction and Parkinson's disease genes: insights from Drosophila.

Park J, Kim Y, Chung J.

Dis Model Mech. 2009 Jul-Aug;2(7-8):336-40. doi: 10.1242/dmm.003178. Review.

PMID:
19553694
[PubMed - indexed for MEDLINE]
Free Article
11.

PINK1 and Parkin complementarily protect dopaminergic neurons in vertebrates.

Matsui H, Gavinio R, Asano T, Uemura N, Ito H, Taniguchi Y, Kobayashi Y, Maki T, Shen J, Takeda S, Uemura K, Yamakado H, Takahashi R.

Hum Mol Genet. 2013 Jun 15;22(12):2423-34. doi: 10.1093/hmg/ddt095. Epub 2013 Feb 27.

PMID:
23449626
[PubMed - indexed for MEDLINE]
Free Article
12.

[Etiology and pathogenesis of Parkinson's disease: from mitochondrial dysfunctions to familial Parkinson's disease].

Hattori N.

Rinsho Shinkeigaku. 2004 Apr-May;44(4-5):241-62. Review. Japanese.

PMID:
15287506
[PubMed - indexed for MEDLINE]
13.

The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila.

Deng H, Dodson MW, Huang H, Guo M.

Proc Natl Acad Sci U S A. 2008 Sep 23;105(38):14503-8. doi: 10.1073/pnas.0803998105. Epub 2008 Sep 17.

PMID:
18799731
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Rhomboid-7 and HtrA2/Omi act in a common pathway with the Parkinson's disease factors Pink1 and Parkin.

Whitworth AJ, Lee JR, Ho VM, Flick R, Chowdhury R, McQuibban GA.

Dis Model Mech. 2008 Sep-Oct;1(2-3):168-74; discussion 173. doi: 10.1242/dmm.000109. Epub 2008 Sep 18.

PMID:
19048081
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Pink1 suppresses alpha-synuclein-induced phenotypes in a Drosophila model of Parkinson's disease.

Todd AM, Staveley BE.

Genome. 2008 Dec;51(12):1040-6. doi: 10.1139/G08-085.

PMID:
19088817
[PubMed - indexed for MEDLINE]
16.

Drosophila Trap1 protects against mitochondrial dysfunction in a PINK1/parkin model of Parkinson's disease.

Costa AC, Loh SH, Martins LM.

Cell Death Dis. 2013 Jan 17;4:e467. doi: 10.1038/cddis.2012.205.

PMID:
23328674
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

The PINK1-Parkin pathway is involved in the regulation of mitochondrial remodeling process.

Park J, Lee G, Chung J.

Biochem Biophys Res Commun. 2009 Jan 16;378(3):518-23. doi: 10.1016/j.bbrc.2008.11.086. Epub 2008 Dec 3.

PMID:
19056353
[PubMed - indexed for MEDLINE]
18.

Mitochondrial dynamics, cell death and the pathogenesis of Parkinson's disease.

Büeler H.

Apoptosis. 2010 Nov;15(11):1336-53. doi: 10.1007/s10495-010-0465-0. Review.

PMID:
20131004
[PubMed - indexed for MEDLINE]
19.

Parkin blushed by PINK1.

Tan JM, Dawson TM.

Neuron. 2006 May 18;50(4):527-9. Review.

PMID:
16701203
[PubMed - indexed for MEDLINE]
Free Article
20.

Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling.

Yang Y, Gehrke S, Haque ME, Imai Y, Kosek J, Yang L, Beal MF, Nishimura I, Wakamatsu K, Ito S, Takahashi R, Lu B.

Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13670-5. Epub 2005 Sep 9.

PMID:
16155123
[PubMed - indexed for MEDLINE]
Free PMC Article

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