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Results: 1 to 20 of 396

1.

Nuclear orphan receptor TAK1/TR4-deficient mice are protected against obesity-linked inflammation, hepatic steatosis, and insulin resistance.

Kang HS, Okamoto K, Kim YS, Takeda Y, Bortner CD, Dang H, Wada T, Xie W, Yang XP, Liao G, Jetten AM.

Diabetes. 2011 Jan;60(1):177-88. doi: 10.2337/db10-0628. Epub 2010 Sep 23.

PMID:
20864514
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Transcriptional profiling reveals a role for RORalpha in regulating gene expression in obesity-associated inflammation and hepatic steatosis.

Kang HS, Okamoto K, Takeda Y, Beak JY, Gerrish K, Bortner CD, DeGraff LM, Wada T, Xie W, Jetten AM.

Physiol Genomics. 2011 Jul 14;43(13):818-28. doi: 10.1152/physiolgenomics.00206.2010. Epub 2011 May 3.

PMID:
21540300
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

CD44 plays a critical role in regulating diet-induced adipose inflammation, hepatic steatosis, and insulin resistance.

Kang HS, Liao G, DeGraff LM, Gerrish K, Bortner CD, Garantziotis S, Jetten AM.

PLoS One. 2013;8(3):e58417. doi: 10.1371/journal.pone.0058417. Epub 2013 Mar 7.

PMID:
23505504
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Dietary capsaicin reduces obesity-induced insulin resistance and hepatic steatosis in obese mice fed a high-fat diet.

Kang JH, Goto T, Han IS, Kawada T, Kim YM, Yu R.

Obesity (Silver Spring). 2010 Apr;18(4):780-7. doi: 10.1038/oby.2009.301. Epub 2009 Oct 1.

PMID:
19798065
[PubMed - indexed for MEDLINE]
5.

Altered endocannabinoid signalling after a high-fat diet in Apoe(-/-) mice: relevance to adipose tissue inflammation, hepatic steatosis and insulin resistance.

Bartelt A, Orlando P, Mele C, Ligresti A, Toedter K, Scheja L, Heeren J, Di Marzo V.

Diabetologia. 2011 Nov;54(11):2900-10. doi: 10.1007/s00125-011-2274-6. Epub 2011 Aug 17.

PMID:
21847582
[PubMed - indexed for MEDLINE]
6.

CD40 deficiency in mice exacerbates obesity-induced adipose tissue inflammation, hepatic steatosis, and insulin resistance.

Guo CA, Kogan S, Amano SU, Wang M, Dagdeviren S, Friedline RH, Aouadi M, Kim JK, Czech MP.

Am J Physiol Endocrinol Metab. 2013 May 1;304(9):E951-63. doi: 10.1152/ajpendo.00514.2012. Epub 2013 Mar 12.

PMID:
23482447
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

P-selectin glycoprotein ligand-1 deficiency is protective against obesity-related insulin resistance.

Sato C, Shikata K, Hirota D, Sasaki M, Nishishita S, Miyamoto S, Kodera R, Ogawa D, Tone A, Kataoka HU, Wada J, Kajitani N, Makino H.

Diabetes. 2011 Jan;60(1):189-99. doi: 10.2337/db09-1894. Epub 2010 Oct 22.

PMID:
20971965
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Cannabinoid CB2 receptor potentiates obesity-associated inflammation, insulin resistance and hepatic steatosis.

Deveaux V, Cadoudal T, Ichigotani Y, Teixeira-Clerc F, Louvet A, Manin S, Nhieu JT, Belot MP, Zimmer A, Even P, Cani PD, Knauf C, Burcelin R, Bertola A, Le Marchand-Brustel Y, Gual P, Mallat A, Lotersztajn S.

PLoS One. 2009 Jun 9;4(6):e5844. doi: 10.1371/journal.pone.0005844.

PMID:
19513120
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

FGFR4 prevents hyperlipidemia and insulin resistance but underlies high-fat diet induced fatty liver.

Huang X, Yang C, Luo Y, Jin C, Wang F, McKeehan WL.

Diabetes. 2007 Oct;56(10):2501-10. Epub 2007 Jul 30.

PMID:
17664243
[PubMed - indexed for MEDLINE]
Free Article
10.

Interleukin-1╬▓ regulates fat-liver crosstalk in obesity by auto-paracrine modulation of adipose tissue inflammation and expandability.

Nov O, Shapiro H, Ovadia H, Tarnovscki T, Dvir I, Shemesh E, Kovsan J, Shelef I, Carmi Y, Voronov E, Apte RN, Lewis E, Haim Y, Konrad D, Bashan N, Rudich A.

PLoS One. 2013;8(1):e53626. doi: 10.1371/journal.pone.0053626. Epub 2013 Jan 16.

PMID:
23341960
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Deletion of Fas in adipocytes relieves adipose tissue inflammation and hepatic manifestations of obesity in mice.

Wueest S, Rapold RA, Schumann DM, Rytka JM, Schildknecht A, Nov O, Chervonsky AV, Rudich A, Schoenle EJ, Donath MY, Konrad D.

J Clin Invest. 2010 Jan;120(1):191-202. doi: 10.1172/JCI38388. Epub 2009 Dec 1.

PMID:
19955656
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Selective inactivation of c-Jun NH2-terminal kinase in adipose tissue protects against diet-induced obesity and improves insulin sensitivity in both liver and skeletal muscle in mice.

Zhang X, Xu A, Chung SK, Cresser JH, Sweeney G, Wong RL, Lin A, Lam KS.

Diabetes. 2011 Feb;60(2):486-95. doi: 10.2337/db10-0650.

PMID:
21270260
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Combined effects of rosiglitazone and conjugated linoleic acid on adiposity, insulin sensitivity, and hepatic steatosis in high-fat-fed mice.

Liu LF, Purushotham A, Wendel AA, Belury MA.

Am J Physiol Gastrointest Liver Physiol. 2007 Jun;292(6):G1671-82. Epub 2007 Feb 22.

PMID:
17322064
[PubMed - indexed for MEDLINE]
Free Article
14.

Targeted overexpression of inducible 6-phosphofructo-2-kinase in adipose tissue increases fat deposition but protects against diet-induced insulin resistance and inflammatory responses.

Huo Y, Guo X, Li H, Xu H, Halim V, Zhang W, Wang H, Fan YY, Ong KT, Woo SL, Chapkin RS, Mashek DG, Chen Y, Dong H, Lu F, Wei L, Wu C.

J Biol Chem. 2012 Jun 15;287(25):21492-500. doi: 10.1074/jbc.M112.370379. Epub 2012 May 3.

PMID:
22556414
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Liver-specific suppressor of cytokine signaling-3 deletion in mice enhances hepatic insulin sensitivity and lipogenesis resulting in fatty liver and obesity.

Sachithanandan N, Fam BC, Fynch S, Dzamko N, Watt MJ, Wormald S, Honeyman J, Galic S, Proietto J, Andrikopoulos S, Hevener AL, Kay TW, Steinberg GR.

Hepatology. 2010 Nov;52(5):1632-42. doi: 10.1002/hep.23861.

PMID:
20799351
[PubMed - indexed for MEDLINE]
16.

The C3a anaphylatoxin receptor is a key mediator of insulin resistance and functions by modulating adipose tissue macrophage infiltration and activation.

Mamane Y, Chung Chan C, Lavallee G, Morin N, Xu LJ, Huang J, Gordon R, Thomas W, Lamb J, Schadt EE, Kennedy BP, Mancini JA.

Diabetes. 2009 Sep;58(9):2006-17. doi: 10.2337/db09-0323. Epub 2009 Jul 6.

PMID:
19581423
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Enhanced Nrf2 activity worsens insulin resistance, impairs lipid accumulation in adipose tissue, and increases hepatic steatosis in leptin-deficient mice.

Xu J, Kulkarni SR, Donepudi AC, More VR, Slitt AL.

Diabetes. 2012 Dec;61(12):3208-18. doi: 10.2337/db11-1716. Epub 2012 Aug 30.

PMID:
22936178
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Hepatic SIRT1 attenuates hepatic steatosis and controls energy balance in mice by inducing fibroblast growth factor 21.

Li Y, Wong K, Giles A, Jiang J, Lee JW, Adams AC, Kharitonenkov A, Yang Q, Gao B, Guarente L, Zang M.

Gastroenterology. 2014 Feb;146(2):539-49.e7. doi: 10.1053/j.gastro.2013.10.059. Epub 2013 Nov 1.

PMID:
24184811
[PubMed - indexed for MEDLINE]
19.

Attenuation of the cardiovascular and metabolic complications of obesity in CD14 knockout mice.

Roncon-Albuquerque R Jr, Moreira-Rodrigues M, Faria B, Ferreira AP, Cerqueira C, Louren├žo AP, Pestana M, von Hafe P, Leite-Moreira AF.

Life Sci. 2008 Sep 26;83(13-14):502-10. doi: 10.1016/j.lfs.2008.07.021. Epub 2008 Aug 12.

PMID:
18761356
[PubMed - indexed for MEDLINE]
20.

Female mice lacking p47phox have altered adipose tissue gene expression and are protected against high fat-induced obesity.

Ronis MJ, Sharma N, Vantrease J, Borengasser SJ, Ferguson M, Mercer KE, Cleves MA, Gomez-Acevedo H, Badger TM.

Physiol Genomics. 2013 May 1;45(9):351-66. doi: 10.1152/physiolgenomics.00148.2012. Epub 2013 Mar 12.

PMID:
23482812
[PubMed - indexed for MEDLINE]
Free Article

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