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Items: 1 to 20 of 82

1.

Fine mapping of the insulin-induced gene 2 identifies a variant associated with LDL cholesterol and total apolipoprotein B levels.

Do R, Bailey SD, Paré G, Montpetit A, Desbiens K, Hudson TJ, Yusuf S, Bouchard C, Gaudet D, Pérusse L, Anand S, Vohl MC, Pastinen T, Engert JC.

Circ Cardiovasc Genet. 2010 Oct;3(5):454-61. doi: 10.1161/CIRCGENETICS.109.917039. Epub 2010 Sep 21.

2.

The INSIG2 rs7566605 genetic variant does not play a major role in obesity in a sample of 24,722 individuals from four cohorts.

Bressler J, Fornage M, Hanis CL, Kao WH, Lewis CE, McPherson R, Dent R, Mosley TH, Pennacchio LA, Boerwinkle E.

BMC Med Genet. 2009 Jun 12;10:56. doi: 10.1186/1471-2350-10-56.

3.

The single nucleotide polymorphism upstream of insulin-induced gene 2 ( INSIG2) is associated with the prevalence of hypercholesterolaemia, but not with obesity, in Japanese American women.

Oki K, Yamane K, Kamei N, Asao T, Awaya T, Kohno N.

Br J Nutr. 2009 Feb;101(3):322-7. doi: 10.1017/S0007114508006557. Epub 2008 Jun 23.

PMID:
18570692
4.

INSIG2 promoter variant, obesity markers and lipid parameters - No association in a large Slavonic Caucasian population sample.

Hubácek JA, Kuthanová L, Bohuslavová R, Adámková V, Lánská V, Meitinger T, Pfeufer A.

Folia Biol (Praha). 2010;56(3):131-4.

5.

Genetic associations of the INSIG2 rs7566605 polymorphism with obesity-related metabolic traits in Malaysian Malays.

Apalasamy YD, Moy FM, Rampal S, Bulgiba A, Mohamed Z.

Genet Mol Res. 2014 Jul 4;13(3):4904-10. doi: 10.4238/2014.July.4.4.

6.

Association analyses of the INSIG2 polymorphism in the obesity and cholesterol levels of Korean populations.

Cha S, Koo I, Choi SM, Park BL, Kim KS, Kim JR, Shin HD, Kim JY.

BMC Med Genet. 2009 Sep 22;10:96. doi: 10.1186/1471-2350-10-96.

7.

INSIG2 gene polymorphism is associated with increased subcutaneous fat in women and poor response to resistance training in men.

Orkunoglu-Suer FE, Gordish-Dressman H, Clarkson PM, Thompson PD, Angelopoulos TJ, Gordon PM, Moyna NM, Pescatello LS, Visich PS, Zoeller RF, Harmon B, Seip RL, Hoffman EP, Devaney JM.

BMC Med Genet. 2008 Dec 23;9:117. doi: 10.1186/1471-2350-9-117.

8.

INSIG2 gene rs7566605 polymorphism is associated with severe obesity in Japanese.

Hotta K, Nakamura M, Nakata Y, Matsuo T, Kamohara S, Kotani K, Komatsu R, Itoh N, Mineo I, Wada J, Masuzaki H, Yoneda M, Nakajima A, Miyazaki S, Tokunaga K, Kawamoto M, Funahashi T, Hamaguchi K, Yamada K, Hanafusa T, Oikawa S, Yoshimatsu H, Nakao K, Sakata T, Matsuzawa Y, Tanaka K, Kamatani N, Nakamura Y.

J Hum Genet. 2008;53(9):857-62. doi: 10.1007/s10038-008-0317-8. Epub 2008 Jul 10.

9.

Absence of association between the INSIG2 gene polymorphism (rs7566605) and obesity in the European Youth Heart Study (EYHS).

Vimaleswaran KS, Franks PW, Brage S, Sardinha LB, Andersen LB, Wareham NJ, Ekelund U, Loos RJ.

Obesity (Silver Spring). 2009 Jul;17(7):1453-7. doi: 10.1038/oby.2008.650. Epub 2009 Feb 5.

PMID:
19197262
10.

INSIG1 influences obesity-related hypertriglyceridemia in humans.

Smith EM, Zhang Y, Baye TM, Gawrieh S, Cole R, Blangero J, Carless MA, Curran JE, Dyer TD, Abraham LJ, Moses EK, Kissebah AH, Martin LJ, Olivier M.

J Lipid Res. 2010 Apr;51(4):701-8. doi: 10.1194/jlr.M001404. Epub 2009 Oct 21.

11.

Lack of association between a common polymorphism near the INSIG2 gene and BMI, myocardial infarction, and cardiovascular risk factors.

Wiedmann S, Neureuther K, Stark K, Reinhard W, Kallmünzer B, Baessler A, Fischer M, Linsel-Nitschke P, Erdmann J, Schunkert H, Hengstenberg C.

Obesity (Silver Spring). 2009 Jul;17(7):1390-5. doi: 10.1038/oby.2008.669. Epub 2009 Feb 5.

PMID:
19197259
12.

INSIG2 G-102A promoter variant exhibits context-dependent effect on HDL-cholesterol levels but not on BMI in Caucasians.

Hubáček JA, Suchánek P, Lánská V, Piťha J, Adámková V.

Folia Biol (Praha). 2011;57(4):170-2.

13.

Association of morbid obesity with FTO and INSIG2 allelic variants.

Chu X, Erdman R, Susek M, Gerst H, Derr K, Al-Agha M, Wood GC, Hartman C, Yeager S, Blosky MA, Krum W, Stewart WF, Carey D, Benotti P, Still CD, Gerhard GS.

Arch Surg. 2008 Mar;143(3):235-40; discussion 241. doi: 10.1001/archsurg.2007.77.

PMID:
18347269
14.

Potential association of INSIG2 rs7566605 polymorphism with body weight in a Chinese subpopulation.

Yang L, Wu Y, Li H, Yu Z, Li X, Liu Y, Lin X, Chen Y.

Eur J Hum Genet. 2008 Jun;16(6):759-61. doi: 10.1038/ejhg.2008.8. Epub 2008 Feb 13.

15.

INSIG2 gene polymorphism is not associated with obesity in Caucasian, Afro-Caribbean and Indian subjects.

Smith AJ, Cooper JA, Li LK, Humphries SE.

Int J Obes (Lond). 2007 Nov;31(11):1753-5. Epub 2007 May 1.

PMID:
17471297
16.

No association between INSIG2 Gene rs7566605 polymorphism and being overweight in Japanese population.

Tabara Y, Kawamoto R, Osawa H, Nakura J, Makino H, Miki T, Kohara K.

Obesity (Silver Spring). 2008 Jan;16(1):211-5. doi: 10.1038/oby.2007.25.

PMID:
18223638
17.

Controversial association results for INSIG2 on body mass index may be explained by interactions with age and with MC4R.

Malzahn D, Müller-Nurasyid M, Heid IM, Wichmann HE; KORA study group, Bickeböller H.

Eur J Hum Genet. 2014 Oct;22(10):1217-24. doi: 10.1038/ejhg.2014.3. Epub 2014 Feb 12.

18.

A tagging SNP in INSIG2 is associated with obesity-related phenotypes among Samoans.

Deka R, Xu L, Pal P, Toelupe PT, Laumoli TS, Xi H, Zhang G, Weeks DE, McGarvey ST.

BMC Med Genet. 2009 Dec 22;10:143. doi: 10.1186/1471-2350-10-143.

19.

INSIG2 polymorphism is neither associated with BMI nor with phenotypes of lipoprotein metabolism.

Boes E, Kollerits B, Heid IM, Hunt SC, Pichler M, Paulweber B, Coassin S, Adams TD, Hopkins PN, Lingenhel A, Wagner SA, Kronenberg F.

Obesity (Silver Spring). 2008 Apr;16(4):827-33. doi: 10.1038/oby.2007.132. Epub 2008 Jan 31.

PMID:
18239574
20.

Influence of common variants near INSIG2, in FTO, and near MC4R genes on overweight and the metabolic profile in adolescence: the TRAILS (TRacking Adolescents' Individual Lives Survey) Study.

Liem ET, Vonk JM, Sauer PJ, van der Steege G, Oosterom E, Stolk RP, Snieder H.

Am J Clin Nutr. 2010 Feb;91(2):321-8. doi: 10.3945/ajcn.2009.28186. Epub 2009 Dec 9.

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