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Items: 1 to 20 of 116

1.

Novel synthetic small-molecule activators of AMPK as enhancers of autophagy and amyloid-β peptide degradation.

Vingtdeux V, Chandakkar P, Zhao H, d'Abramo C, Davies P, Marambaud P.

FASEB J. 2011 Jan;25(1):219-31. doi: 10.1096/fj.10-167361. Epub 2010 Sep 17.

2.

Small-molecule activators of AMP-activated protein kinase (AMPK), RSVA314 and RSVA405, inhibit adipogenesis.

Vingtdeux V, Chandakkar P, Zhao H, Davies P, Marambaud P.

Mol Med. 2011 Sep-Oct;17(9-10):1022-30. doi: 10.2119/molmed.2011.00163. Epub 2011 Jun 1.

3.

AMP-activated protein kinase signaling activation by resveratrol modulates amyloid-beta peptide metabolism.

Vingtdeux V, Giliberto L, Zhao H, Chandakkar P, Wu Q, Simon JE, Janle EM, Lobo J, Ferruzzi MG, Davies P, Marambaud P.

J Biol Chem. 2010 Mar 19;285(12):9100-13. doi: 10.1074/jbc.M109.060061. Epub 2010 Jan 14.

4.

Aβ peptide secretion is reduced by Radix Polygalae-induced autophagy via activation of the AMPK/mTOR pathway.

Zhao H, Wang ZC, Wang KF, Chen XY.

Mol Med Rep. 2015 Aug;12(2):2771-6. doi: 10.3892/mmr.2015.3781. Epub 2015 May 13.

PMID:
25976650
5.

Roles of AMP-activated protein kinase in Alzheimer's disease.

Cai Z, Yan LJ, Li K, Quazi SH, Zhao B.

Neuromolecular Med. 2012 Mar;14(1):1-14. doi: 10.1007/s12017-012-8173-2. Epub 2012 Feb 26. Review.

PMID:
22367557
6.

Autophagy-dependent and -independent involvement of AMP-activated protein kinase in 6-hydroxydopamine toxicity to SH-SY5Y neuroblastoma cells.

Arsikin K, Kravic-Stevovic T, Jovanovic M, Ristic B, Tovilovic G, Zogovic N, Bumbasirevic V, Trajkovic V, Harhaji-Trajkovic L.

Biochim Biophys Acta. 2012 Nov;1822(11):1826-36. doi: 10.1016/j.bbadis.2012.08.006. Epub 2012 Aug 16.

7.

Chondrocyte autophagy is stimulated by HIF-1 dependent AMPK activation and mTOR suppression.

Bohensky J, Leshinsky S, Srinivas V, Shapiro IM.

Pediatr Nephrol. 2010 Apr;25(4):633-42. doi: 10.1007/s00467-009-1310-y. Epub 2009 Oct 15.

8.

Compound C induces protective autophagy in cancer cells through AMPK inhibition-independent blockade of Akt/mTOR pathway.

Vucicevic L, Misirkic M, Janjetovic K, Vilimanovich U, Sudar E, Isenovic E, Prica M, Harhaji-Trajkovic L, Kravic-Stevovic T, Bumbasirevic V, Trajkovic V.

Autophagy. 2011 Jan;7(1):40-50. Epub 2011 Jan 1.

PMID:
20980833
9.
10.

Glucose regulates amyloid β production via AMPK.

Yang TT, Shih YS, Chen YW, Kuo YM, Lee CW.

J Neural Transm (Vienna). 2015 Oct;122(10):1381-90. doi: 10.1007/s00702-015-1413-5. Epub 2015 Jun 13.

PMID:
26071020
11.

The association of AMPK with ULK1 regulates autophagy.

Lee JW, Park S, Takahashi Y, Wang HG.

PLoS One. 2010 Nov 3;5(11):e15394. doi: 10.1371/journal.pone.0015394.

12.

Apigenin, a chemopreventive bioflavonoid, induces AMP-activated protein kinase activation in human keratinocytes.

Tong X, Smith KA, Pelling JC.

Mol Carcinog. 2012 Mar;51(3):268-79. doi: 10.1002/mc.20793. Epub 2011 May 2.

PMID:
21538580
13.

Aβ-induced formation of autophagosomes is mediated by RAGE-CaMKKβ-AMPK signaling.

Son SM, Jung ES, Shin HJ, Byun J, Mook-Jung I.

Neurobiol Aging. 2012 May;33(5):1006.e11-23. doi: 10.1016/j.neurobiolaging.2011.09.039. Epub 2011 Nov 1.

PMID:
22048125
14.

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1.

Kim J, Kundu M, Viollet B, Guan KL.

Nat Cell Biol. 2011 Feb;13(2):132-41. doi: 10.1038/ncb2152. Epub 2011 Jan 23.

15.

Pterostilbene, a natural small-molecular compound, promotes cytoprotective macroautophagy in vascular endothelial cells.

Zhang L, Cui L, Zhou G, Jing H, Guo Y, Sun W.

J Nutr Biochem. 2013 May;24(5):903-11. doi: 10.1016/j.jnutbio.2012.06.008. Epub 2012 Aug 13.

PMID:
22898568
16.

3,4-Dimethoxystilbene, a resveratrol derivative with anti-angiogenic effect, induces both macroautophagy and apoptosis in endothelial cells.

Zhang L, Jing H, Cui L, Li H, Zhou B, Zhou G, Dai F.

J Cell Biochem. 2013 Mar;114(3):697-707. doi: 10.1002/jcb.24411.

PMID:
23059970
17.

Quercetin attenuates renal ischemia/reperfusion injury via an activation of AMP-activated protein kinase-regulated autophagy pathway.

Chen BL, Wang LT, Huang KH, Wang CC, Chiang CK, Liu SH.

J Nutr Biochem. 2014 Nov;25(11):1226-34. doi: 10.1016/j.jnutbio.2014.05.013. Epub 2014 Jul 4.

PMID:
25087994
18.

Inhibition of glycogen synthase kinase-3 ameliorates β-amyloid pathology and restores lysosomal acidification and mammalian target of rapamycin activity in the Alzheimer disease mouse model: in vivo and in vitro studies.

Avrahami L, Farfara D, Shaham-Kol M, Vassar R, Frenkel D, Eldar-Finkelman H.

J Biol Chem. 2013 Jan 11;288(2):1295-306. doi: 10.1074/jbc.M112.409250. Epub 2012 Nov 15.

19.

Novel role for TRPC4 in regulation of macroautophagy by a small molecule in vascular endothelial cells.

Zhang L, Dai F, Cui L, Jing H, Fan P, Tan X, Guo Y, Zhou G.

Biochim Biophys Acta. 2015 Feb;1853(2):377-87. doi: 10.1016/j.bbamcr.2014.10.030. Epub 2014 Dec 2.

20.

Resveratrol-activated AMPK/SIRT1/autophagy in cellular models of Parkinson's disease.

Wu Y, Li X, Zhu JX, Xie W, Le W, Fan Z, Jankovic J, Pan T.

Neurosignals. 2011;19(3):163-74. doi: 10.1159/000328516. Epub 2011 Jul 22.

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