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Reduction of immune activation with chloroquine therapy during chronic HIV infection.

Murray SM, Down CM, Boulware DR, Stauffer WM, Cavert WP, Schacker TW, Brenchley JM, Douek DC.

J Virol. 2010 Nov;84(22):12082-6. doi: 10.1128/JVI.01466-10. Epub 2010 Sep 15.


Interferon-alpha administration enhances CD8+ T cell activation in HIV infection.

Manion M, Rodriguez B, Medvik K, Hardy G, Harding CV, Schooley RT, Pollard R, Asmuth D, Murphy R, Barker E, Brady KE, Landay A, Funderburg N, Sieg SF, Lederman MM.

PLoS One. 2012;7(1):e30306. doi: 10.1371/journal.pone.0030306. Epub 2012 Jan 24.


The role of extended-release niacin on immune activation and neurocognition in HIV-infected patients treated with antiretroviral therapy - CTN PT006: study protocol for a randomized controlled trial.

Lebouché B, Jenabian MA, Singer J, Graziani GM, Engler K, Trottier B, Thomas R, Brouillette MJ, Routy JP.

Trials. 2014 Oct 7;15:390. doi: 10.1186/1745-6215-15-390.


Role of in vitro stimulation with lipopolysaccharide on T-cell activation in HIV-infected antiretroviral-treated patients.

Tincati C, Bellistrì GM, Ancona G, Merlini E, d'Arminio Monforte A, Marchetti G.

Clin Dev Immunol. 2012;2012:935425. doi: 10.1155/2012/935425. Epub 2012 Feb 15.


Raltegravir intensification shows differing effects on CD8 and CD4 T cells in HIV-infected HAART-suppressed individuals with poor CD4 T-cell recovery.

Massanella M, Negredo E, Puig J, Puertas MC, Buzón MJ, Pérez-Álvarez N, Carrillo J, Clotet B, Martínez-Picado J, Blanco J.

AIDS. 2012 Nov 28;26(18):2285-93. doi: 10.1097/QAD.0b013e328359f20f.


Rapid restoration of CD4 T cell subsets in subjects receiving antiretroviral therapy during primary HIV-1 infection.

Kaufmann GR, Zaunders JJ, Cunningham P, Kelleher AD, Grey P, Smith D, Carr A, Cooper DA.

AIDS. 2000 Dec 1;14(17):2643-51.


Regeneration and tolerance factor: a correlate of human immunodeficiency virus-associated T-cell activation.

Givens TS, DuChateau BK, Boomer JS, Westerman MP, Gilman-Sachs A, Beaman KD.

Clin Diagn Lab Immunol. 1999 Nov;6(6):872-7.


CD8+ T cells specific for EBV, cytomegalovirus, and influenza virus are activated during primary HIV infection.

Doisne JM, Urrutia A, Lacabaratz-Porret C, Goujard C, Meyer L, Chaix ML, Sinet M, Venet A.

J Immunol. 2004 Aug 15;173(4):2410-8.


Rapid whole blood analysis of virus-specific CD4 and CD8 T cell responses in persistent HIV infection.

Sester M, Sester U, Köhler H, Schneider T, Deml L, Wagner R, Mueller-Lantzsch N, Pees HW, Meyerhans A.

AIDS. 2000 Dec 1;14(17):2653-60.


Activation and cell cycle antigens in CD4+ and CD8+ T cells correlate with plasma human immunodeficiency virus (HIV-1) RNA level in HIV-1 infection.

Orendi JM, Bloem AC, Borleffs JC, Wijnholds FJ, de Vos NM, Nottet HS, Visser MR, Snippe H, Verhoef J, Boucher CA.

J Infect Dis. 1998 Nov;178(5):1279-87.


Association of functional impairment with inflammation and immune activation in HIV type 1-infected adults receiving effective antiretroviral therapy.

Erlandson KM, Allshouse AA, Jankowski CM, Lee EJ, Rufner KM, Palmer BE, Wilson CC, MaWhinney S, Kohrt WM, Campbell TB.

J Infect Dis. 2013 Jul 15;208(2):249-59. doi: 10.1093/infdis/jit147. Epub 2013 Apr 4.


Correlation of CD8 lymphocyte activation with cellular viremia and plasma HIV RNA levels in asymptomatic patients infected by human immunodeficiency virus type 1.

Bouscarat F, Levacher-Clergeot M, Dazza MC, Strauss KW, Girard PM, Ruggeri C, Sinet M.

AIDS Res Hum Retroviruses. 1996 Jan 1;12(1):17-24.


Cd38 expression on Cd8+ T cells in Human immunodeficiency virus 1-positive adults treated with HAART.

Beran O, Holub M, Spála J, Kalanin J, Stanková M.

Acta Virol. 2003;47(2):121-4.


Cell cycling in HIV infection: analysis of in vivo activated lymphocytes.

Mahalingam M, Pozniak A, McManus TJ, Vergani D, Peakman M.

Clin Exp Immunol. 1995 Dec;102(3):481-6.


T cell receptor excision circle (TREC) content following maximum HIV suppression is equivalent in HIV-infected and HIV-uninfected individuals.

Steffens CM, Smith KY, Landay A, Shott S, Truckenbrod A, Russert M, Al-Harthi L.

AIDS. 2001 Sep 28;15(14):1757-64.


Combined Env- and Gag-specific T cell responses in relation to programmed death-1 receptor and CD4 T cell loss rates in human immunodeficiency virus-1 infection.

Pettersen FO, Taskén K, Kvale D.

Clin Exp Immunol. 2010 Aug;161(2):315-23. doi: 10.1111/j.1365-2249.2010.04179.x. Epub 2010 May 10.


Antiretroviral therapy corrects HIV-1-induced expansion of CD8+ CD45RA+ CD2-) CD11a(bright) activated T cells.

Yin L, Rodriguez CA, Hou W, Potter O, Caplan MJ, Goodenow MM, Sleasman JW.

J Allergy Clin Immunol. 2008 Jul;122(1):166-72, 172.e1-2. doi: 10.1016/j.jaci.2008.04.029. Epub 2008 Jun 9.


CD4+ and CD8+ T cells expressing FoxP3 in HIV-infected patients are phenotypically distinct and influenced by disease severity and antiretroviral therapy.

Lim A, French MA, Price P.

J Acquir Immune Defic Syndr. 2009 Jul 1;51(3):248-57. doi: 10.1097/QAI.0b013e3181a74fad.

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