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Results: 1 to 20 of 106

1.

Expression of proliferative and inflammatory markers in a full-thickness human skin equivalent following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide.

Black AT, Hayden PJ, Casillas RP, Heck DE, Gerecke DR, Sinko PJ, Laskin DL, Laskin JD.

Toxicol Appl Pharmacol. 2010 Dec 1;249(2):178-87. doi: 10.1016/j.taap.2010.09.005. Epub 2010 Sep 16.

PMID:
20840853
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Role of MAP kinases in regulating expression of antioxidants and inflammatory mediators in mouse keratinocytes following exposure to the half mustard, 2-chloroethyl ethyl sulfide.

Black AT, Joseph LB, Casillas RP, Heck DE, Gerecke DR, Sinko PJ, Laskin DL, Laskin JD.

Toxicol Appl Pharmacol. 2010 Jun 15;245(3):352-60. doi: 10.1016/j.taap.2010.04.001. Epub 2010 Apr 9.

PMID:
20382172
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Regulation of Hsp27 and Hsp70 expression in human and mouse skin construct models by caveolae following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide.

Black AT, Hayden PJ, Casillas RP, Heck DE, Gerecke DR, Sinko PJ, Laskin DL, Laskin JD.

Toxicol Appl Pharmacol. 2011 Jun 1;253(2):112-20. doi: 10.1016/j.taap.2011.03.015. Epub 2011 Mar 30.

PMID:
21457723
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Il-1-related cytokine responses of nonimmune skin cells subjected to CEES exposure with and without potential vesicant antagonists.

Blaha M, Bowers W Jr, Kohl J, DuBose D, Walker J.

In Vitr Mol Toxicol. 2000 Summer;13(2):99-111.

PMID:
11031321
[PubMed - indexed for MEDLINE]
5.

Inflammatory biomarkers of sulfur mustard analog 2-chloroethyl ethyl sulfide-induced skin injury in SKH-1 hairless mice.

Tewari-Singh N, Rana S, Gu M, Pal A, Orlicky DJ, White CW, Agarwal R.

Toxicol Sci. 2009 Mar;108(1):194-206. doi: 10.1093/toxsci/kfn261. Epub 2008 Dec 15.

PMID:
19075041
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Structural changes in the skin of hairless mice following exposure to sulfur mustard correlate with inflammation and DNA damage.

Joseph LB, Gerecke DR, Heck DE, Black AT, Sinko PJ, Cervelli JA, Casillas RP, Babin MC, Laskin DL, Laskin JD.

Exp Mol Pathol. 2011 Oct;91(2):515-27. doi: 10.1016/j.yexmp.2011.05.010. Epub 2011 Jun 13.

PMID:
21672537
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Role of TNFR1 in lung injury and altered lung function induced by the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide.

Sunil VR, Patel-Vayas K, Shen J, Gow AJ, Laskin JD, Laskin DL.

Toxicol Appl Pharmacol. 2011 Feb 1;250(3):245-55. doi: 10.1016/j.taap.2010.10.027. Epub 2010 Nov 9.

PMID:
21070800
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

2,6-Dithiopurine, a nucleophilic scavenger, protects against mutagenesis in mouse skin treated in vivo with 2-(chloroethyl) ethyl sulfide, a mustard gas analog.

Boulware S, Fields T, McIvor E, Powell KL, Abel EL, Vasquez KM, MacLeod MC.

Toxicol Appl Pharmacol. 2012 Sep 1;263(2):203-9. doi: 10.1016/j.taap.2012.06.010. Epub 2012 Jun 23.

PMID:
22732900
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Sulfur mustard analog, 2-chloroethyl ethyl sulfide-induced skin injury involves DNA damage and induction of inflammatory mediators, in part via oxidative stress, in SKH-1 hairless mouse skin.

Jain AK, Tewari-Singh N, Gu M, Inturi S, White CW, Agarwal R.

Toxicol Lett. 2011 Sep 10;205(3):293-301. doi: 10.1016/j.toxlet.2011.06.019. Epub 2011 Jun 21.

PMID:
21722719
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

A double-label technique that monitors sulfur mustard damage to nuclei and mitochondria of normal human epidermal keratinocytes in vitro.

Cook JR, Van Buskirk RG.

Toxicol Pathol. 1997 Sep-Oct;25(5):481-6.

PMID:
9323838
[PubMed - indexed for MEDLINE]
Free Article
11.

Inhibition of NADPH cytochrome P450 reductase by the model sulfur mustard vesicant 2-chloroethyl ethyl sulfide is associated with increased production of reactive oxygen species.

Gray JP, Mishin V, Heck DE, Laskin DL, Laskin JD.

Toxicol Appl Pharmacol. 2010 Sep 1;247(2):76-82. doi: 10.1016/j.taap.2010.05.015. Epub 2010 Jun 2.

PMID:
20561902
[PubMed - indexed for MEDLINE]
12.

Silibinin attenuates sulfur mustard analog-induced skin injury by targeting multiple pathways connecting oxidative stress and inflammation.

Tewari-Singh N, Jain AK, Inturi S, Agarwal C, White CW, Agarwal R.

PLoS One. 2012;7(9):e46149. doi: 10.1371/journal.pone.0046149. Epub 2012 Sep 27.

PMID:
23029417
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Effects of CEES on inflammatory mediators, heat shock protein 70A, histology and ultrastructure in two skin models.

Blaha M, Bowers W Jr, Kohl J, DuBose D, Walker J, Alkhyyat A, Wong G.

J Appl Toxicol. 2000 Dec;20 Suppl 1:S101-8.

PMID:
11428619
[PubMed - indexed for MEDLINE]
14.

Catalytic antioxidant AEOL 10150 treatment ameliorates sulfur mustard analog 2-chloroethyl ethyl sulfide-associated cutaneous toxic effects.

Tewari-Singh N, Inturi S, Jain AK, Agarwal C, Orlicky DJ, White CW, Agarwal R, Day BJ.

Free Radic Biol Med. 2014 Jul;72:285-95. doi: 10.1016/j.freeradbiomed.2014.04.022. Epub 2014 May 9.

PMID:
24815113
[PubMed - indexed for MEDLINE]
15.

Mechanisms of sulfur mustard analog 2-chloroethyl ethyl sulfide-induced DNA damage in skin epidermal cells and fibroblasts.

Inturi S, Tewari-Singh N, Gu M, Shrotriya S, Gomez J, Agarwal C, White CW, Agarwal R.

Free Radic Biol Med. 2011 Dec 15;51(12):2272-80. doi: 10.1016/j.freeradbiomed.2011.08.020. Epub 2011 Aug 26.

PMID:
21920433
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Biological and molecular mechanisms of sulfur mustard analogue-induced toxicity in JB6 and HaCaT cells: possible role of ataxia telangiectasia-mutated/ataxia telangiectasia-Rad3-related cell cycle checkpoint pathway.

Tewari-Singh N, Gu M, Agarwal C, White CW, Agarwal R.

Chem Res Toxicol. 2010 Jun 21;23(6):1034-44. doi: 10.1021/tx100038b.

PMID:
20469912
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Efficacy of glutathione in ameliorating sulfur mustard analog-induced toxicity in cultured skin epidermal cells and in SKH-1 mouse skin in vivo.

Tewari-Singh N, Agarwal C, Huang J, Day BJ, White CW, Agarwal R.

J Pharmacol Exp Ther. 2011 Feb;336(2):450-9. doi: 10.1124/jpet.110.173708. Epub 2010 Oct 25. Review.

PMID:
20974699
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Modified immunoslotblot assay to detect hemi and sulfur mustard DNA adducts.

Kehe K, Schrettl V, Thiermann H, Steinritz D.

Chem Biol Interact. 2013 Dec 5;206(3):523-8. doi: 10.1016/j.cbi.2013.08.001. Epub 2013 Aug 8.

PMID:
23933409
[PubMed - indexed for MEDLINE]
19.

Protection against 2-chloroethyl ethyl sulfide (CEES)-induced cytotoxicity in human keratinocytes by an inducer of the glutathione detoxification pathway.

Abel EL, Bubel JD, Simper MS, Powell L, McClellan SA, Andreeff M, MacLeod MC, DiGiovanni J.

Toxicol Appl Pharmacol. 2011 Sep 1;255(2):176-83. doi: 10.1016/j.taap.2011.06.012. Epub 2011 Jun 23.

PMID:
21723306
[PubMed - indexed for MEDLINE]
20.

2,6-Dithiopurine blocks toxicity and mutagenesis in human skin cells exposed to sulfur mustard analogues, 2-chloroethyl ethyl sulfide and 2-chloroethyl methyl sulfide.

Powell KL, Boulware S, Thames H, Vasquez KM, MacLeod MC.

Chem Res Toxicol. 2010 Mar 15;23(3):497-503. doi: 10.1021/tx9001918.

PMID:
20050631
[PubMed - indexed for MEDLINE]
Free PMC Article

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