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Results: 1 to 20 of 115

1.

Autophagy induction with RAD001 enhances chemosensitivity and radiosensitivity through Met inhibition in papillary thyroid cancer.

Lin CI, Whang EE, Donner DB, Du J, Lorch J, He F, Jiang X, Price BD, Moore FD Jr, Ruan DT.

Mol Cancer Res. 2010 Sep;8(9):1217-26. doi: 10.1158/1541-7786.MCR-10-0162. Epub 2010 Aug 24.

PMID:
20736296
[PubMed - indexed for MEDLINE]
Free Article
2.

Autophagy: a new target for advanced papillary thyroid cancer therapy.

Lin CI, Whang EE, Abramson MA, Jiang X, Price BD, Donner DB, Moore FD Jr, Ruan DT.

Surgery. 2009 Dec;146(6):1208-14. doi: 10.1016/j.surg.2009.09.019.

PMID:
19958950
[PubMed - indexed for MEDLINE]
3.

Galectin-3 targeted therapy with a small molecule inhibitor activates apoptosis and enhances both chemosensitivity and radiosensitivity in papillary thyroid cancer.

Lin CI, Whang EE, Donner DB, Jiang X, Price BD, Carothers AM, Delaine T, Leffler H, Nilsson UJ, Nose V, Moore FD Jr, Ruan DT.

Mol Cancer Res. 2009 Oct;7(10):1655-62. doi: 10.1158/1541-7786.MCR-09-0274. Epub 2009 Oct 13.

PMID:
19825987
[PubMed - indexed for MEDLINE]
Free Article
4.

Small molecule c-MET inhibitor PHA665752: effect on cell growth and motility in papillary thyroid carcinoma.

Chattopadhyay C, El-Naggar AK, Williams MD, Clayman GL.

Head Neck. 2008 Aug;30(8):991-1000. doi: 10.1002/hed.20816.

PMID:
18327775
[PubMed - indexed for MEDLINE]
5.

Synergistic tumor-killing effect of radiation and berberine combined treatment in lung cancer: the contribution of autophagic cell death.

Peng PL, Kuo WH, Tseng HC, Chou FP.

Int J Radiat Oncol Biol Phys. 2008 Feb 1;70(2):529-42. doi: 10.1016/j.ijrobp.2007.08.034.

PMID:
18207031
[PubMed - indexed for MEDLINE]
6.

The combination of RAD001 and MK-2206 exerts synergistic cytotoxic effects against PTEN mutant gastric cancer cells: involvement of MAPK-dependent autophagic, but not apoptotic cell death pathway.

Ji D, Zhang Z, Cheng L, Chang J, Wang S, Zheng B, Zheng R, Sun Z, Wang C, Zhang Z, Liu R, Zhang X, Liu X, Wang X, Li J.

PLoS One. 2014 Jan 9;9(1):e85116. doi: 10.1371/journal.pone.0085116. eCollection 2014.

PMID:
24416349
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The rapamycin-derivative RAD001 (everolimus) inhibits cell viability and interacts with the Akt-mTOR-p70S6K pathway in human medullary thyroid carcinoma cells.

Grozinsky-Glasberg S, Rubinfeld H, Nordenberg Y, Gorshtein A, Praiss M, Kendler E, Feinmesser R, Grossman AB, Shimon I.

Mol Cell Endocrinol. 2010 Feb 5;315(1-2):87-94. doi: 10.1016/j.mce.2009.09.027. Epub 2009 Oct 6.

PMID:
19815051
[PubMed - indexed for MEDLINE]
8.

Delta-24-RGD in combination with RAD001 induces enhanced anti-glioma effect via autophagic cell death.

Alonso MM, Jiang H, Yokoyama T, Xu J, Bekele NB, Lang FF, Kondo S, Gomez-Manzano C, Fueyo J.

Mol Ther. 2008 Mar;16(3):487-93. doi: 10.1038/sj.mt.6300400. Epub 2008 Feb 5.

PMID:
18253154
[PubMed - indexed for MEDLINE]
9.

Inhibition of mammalian target of rapamycin or apoptotic pathway induces autophagy and radiosensitizes PTEN null prostate cancer cells.

Cao C, Subhawong T, Albert JM, Kim KW, Geng L, Sekhar KR, Gi YJ, Lu B.

Cancer Res. 2006 Oct 15;66(20):10040-7.

PMID:
17047067
[PubMed - indexed for MEDLINE]
Free Article
10.

Targeting the Akt/mammalian target of rapamycin pathway for radiosensitization of breast cancer.

Albert JM, Kim KW, Cao C, Lu B.

Mol Cancer Ther. 2006 May;5(5):1183-9.

PMID:
16731750
[PubMed - indexed for MEDLINE]
Free Article
11.

The activity of mTOR inhibitor RAD001 (everolimus) in nasopharyngeal carcinoma and cisplatin-resistant cell lines.

Ma BB, Lui VW, Hui EP, Lau CP, Ho K, Ng MH, Cheng SH, Tsao SW, Chan AT.

Invest New Drugs. 2010 Aug;28(4):413-20. doi: 10.1007/s10637-009-9269-x. Epub 2009 May 27.

PMID:
19471857
[PubMed - indexed for MEDLINE]
12.

Genome-wide expression analysis of Middle Eastern papillary thyroid cancer reveals c-MET as a novel target for cancer therapy.

Siraj AK, Bavi P, Abubaker J, Jehan Z, Sultana M, Al-Dayel F, Al-Nuaim A, Alzahrani A, Ahmed M, Al-Sanea O, Uddin S, Al-Kuraya KS.

J Pathol. 2007 Oct;213(2):190-9.

PMID:
17703498
[PubMed - indexed for MEDLINE]
13.

RAD001 (Everolimus) induces autophagy in acute lymphoblastic leukemia.

Crazzolara R, Bradstock KF, Bendall LJ.

Autophagy. 2009 Jul;5(5):727-8. Epub 2009 Jul 23.

PMID:
19363300
[PubMed - indexed for MEDLINE]
Free Article
14.

Bacillus calmette-guerin cell wall cytoskeleton enhances colon cancer radiosensitivity through autophagy.

Yuk JM, Shin DM, Song KS, Lim K, Kim KH, Lee SH, Kim JM, Lee JS, Paik TH, Kim JS, Jo EK.

Autophagy. 2010 Jan;6(1):46-60. Epub 2010 Jan 13.

PMID:
19901560
[PubMed - indexed for MEDLINE]
Free Article
15.

Higher levels of c-Met expression and phosphorylation identify cell lines with increased sensitivity to AMG-458, a novel selective c-Met inhibitor with radiosensitizing effects.

Li B, Torossian A, Sun Y, Du R, Dicker AP, Lu B.

Int J Radiat Oncol Biol Phys. 2012 Nov 15;84(4):e525-31. doi: 10.1016/j.ijrobp.2012.06.025. Epub 2012 Jul 24.

PMID:
22836051
[PubMed - indexed for MEDLINE]
16.

Modulatory role of phospholipase D in the activation of signal transducer and activator of transcription (STAT)-3 by thyroid oncogenic kinase RET/PTC.

Kim YR, Byun HS, Won M, Park KA, Kim JM, Choi BL, Lee H, Hong JH, Park J, Seok JH, Kim DW, Shong M, Park SK, Hur GM.

BMC Cancer. 2008 May 23;8:144. doi: 10.1186/1471-2407-8-144.

PMID:
18498667
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition.

Armstrong JL, Corazzari M, Martin S, Pagliarini V, Falasca L, Hill DS, Ellis N, Al Sabah S, Redfern CP, Fimia GM, Piacentini M, Lovat PE.

Clin Cancer Res. 2011 Apr 15;17(8):2216-26. doi: 10.1158/1078-0432.CCR-10-3003. Epub 2011 Jan 26.

PMID:
21270111
[PubMed - indexed for MEDLINE]
Free Article
18.

Transcription factor GATA4 inhibits doxorubicin-induced autophagy and cardiomyocyte death.

Kobayashi S, Volden P, Timm D, Mao K, Xu X, Liang Q.

J Biol Chem. 2010 Jan 1;285(1):793-804. doi: 10.1074/jbc.M109.070037. Epub 2009 Nov 9.

PMID:
19901028
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Poly(ADP-ribose) polymerase-1 regulates the mechanism of irradiation-induced CNE-2 human nasopharyngeal carcinoma cell autophagy and inhibition of autophagy contributes to the radiation sensitization of CNE-2 cells.

Zhou ZR, Zhu XD, Zhao W, Qu S, Su F, Huang ST, Ma JL, Li XY.

Oncol Rep. 2013 Jun;29(6):2498-506. doi: 10.3892/or.2013.2382. Epub 2013 Apr 4.

PMID:
23563481
[PubMed - indexed for MEDLINE]
20.

Autophagic activation potentiates the antiproliferative effects of tyrosine kinase inhibitors in medullary thyroid cancer.

Lin CI, Whang EE, Lorch JH, Ruan DT.

Surgery. 2012 Dec;152(6):1142-9. doi: 10.1016/j.surg.2012.08.016.

PMID:
23158184
[PubMed - indexed for MEDLINE]
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