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Results: 1 to 20 of 231

1.

Nicotinic acetylcholine receptor genes on chromosome 15q25.1 are associated with nicotine and opioid dependence severity.

Erlich PM, Hoffman SN, Rukstalis M, Han JJ, Chu X, Linda Kao WH, Gerhard GS, Stewart WF, Boscarino JA.

Hum Genet. 2010 Nov;128(5):491-9. doi: 10.1007/s00439-010-0876-6. Epub 2010 Aug 20.

PMID:
20725741
[PubMed - indexed for MEDLINE]
2.

Risk gene variants for nicotine dependence in the CHRNA5-CHRNA3-CHRNB4 cluster are associated with cognitive performance.

Winterer G, Mittelstrass K, Giegling I, Lamina C, Fehr C, Brenner H, Breitling LP, Nitz B, Raum E, Müller H, Gallinat J, Gal A, Heim K, Prokisch H, Meitinger T, Hartmann AM, Möller HJ, Gieger C, Wichmann HE, Illig T, Dahmen N, Rujescu D.

Am J Med Genet B Neuropsychiatr Genet. 2010 Dec 5;153B(8):1448-58. doi: 10.1002/ajmg.b.31126. Epub 2010 Sep 30.

PMID:
20886544
[PubMed - indexed for MEDLINE]
3.

Association of nicotinic acetylcholine receptor subunit alpha 4 polymorphisms with nicotine dependence in 5500 Germans.

Breitling LP, Dahmen N, Mittelstrass K, Rujescu D, Gallinat J, Fehr C, Giegling I, Lamina C, Illig T, Müller H, Raum E, Rothenbacher D, Wichmann HE, Brenner H, Winterer G.

Pharmacogenomics J. 2009 Aug;9(4):219-24. doi: 10.1038/tpj.2009.6. Epub 2009 Mar 17.

PMID:
19290018
[PubMed - indexed for MEDLINE]
4.

Variant within the promoter region of the CHRNA3 gene associated with FTN dependence is not related to self-reported willingness to quit smoking.

Marques-Vidal P, Kutalik Z, Paccaud F, Bergmann S, Waeber G, Vollenweider P, Cornuz J.

Nicotine Tob Res. 2011 Sep;13(9):833-9. doi: 10.1093/ntr/ntr084. Epub 2011 Apr 21.

PMID:
21511889
[PubMed - indexed for MEDLINE]
5.

Variation in nicotinic acetylcholine receptor genes is associated with multiple substance dependence phenotypes.

Sherva R, Kranzler HR, Yu Y, Logue MW, Poling J, Arias AJ, Anton RF, Oslin D, Farrer LA, Gelernter J.

Neuropsychopharmacology. 2010 Aug;35(9):1921-31. doi: 10.1038/npp.2010.64. Epub 2010 May 19.

PMID:
20485328
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Association of genes coding for the alpha-4, alpha-5, beta-2 and beta-3 subunits of nicotinic receptors with cigarette smoking and nicotine dependence.

Etter JF, Hoda JC, Perroud N, Munafò M, Buresi C, Duret C, Neidhart E, Malafosse A, Bertrand D.

Addict Behav. 2009 Sep;34(9):772-5. doi: 10.1016/j.addbeh.2009.05.010. Epub 2009 May 22.

PMID:
19482438
[PubMed - indexed for MEDLINE]
7.

Nicotine dependence may link the 15q25 locus to lung cancer risk.

Galvan A, Dragani TA.

Carcinogenesis. 2010 Mar;31(3):331-3. doi: 10.1093/carcin/bgp282. Epub 2009 Nov 12.

PMID:
19910382
[PubMed - indexed for MEDLINE]
Free Article
8.

A candidate gene approach identifies the CHRNA5-A3-B4 region as a risk factor for age-dependent nicotine addiction.

Weiss RB, Baker TB, Cannon DS, von Niederhausern A, Dunn DM, Matsunami N, Singh NA, Baird L, Coon H, McMahon WM, Piper ME, Fiore MC, Scholand MB, Connett JE, Kanner RE, Gahring LC, Rogers SW, Hoidal JR, Leppert MF.

PLoS Genet. 2008 Jul 11;4(7):e1000125. doi: 10.1371/journal.pgen.1000125.

PMID:
18618000
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans.

Saccone NL, Wang JC, Breslau N, Johnson EO, Hatsukami D, Saccone SF, Grucza RA, Sun L, Duan W, Budde J, Culverhouse RC, Fox L, Hinrichs AL, Steinbach JH, Wu M, Rice JP, Goate AM, Bierut LJ.

Cancer Res. 2009 Sep 1;69(17):6848-56. doi: 10.1158/0008-5472.CAN-09-0786. Epub 2009 Aug 25.

PMID:
19706762
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

The polymorphism of the CHRNA5 gene and the strength of nicotine addiction in lung cancer and COPD patients.

Wojas-Krawczyk K, Krawczyk P, Biernacka B, Grzybek M, Kołodziej P, Kucharczyk T, Mlak R, Milanowski J.

Eur J Cancer Prev. 2012 Mar;21(2):111-7. doi: 10.1097/CEJ.0b013e32834c9b40.

PMID:
21955800
[PubMed - indexed for MEDLINE]
11.

Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD.

Saccone NL, Culverhouse RC, Schwantes-An TH, Cannon DS, Chen X, Cichon S, Giegling I, Han S, Han Y, Keskitalo-Vuokko K, Kong X, Landi MT, Ma JZ, Short SE, Stephens SH, Stevens VL, Sun L, Wang Y, Wenzlaff AS, Aggen SH, Breslau N, Broderick P, Chatterjee N, Chen J, Heath AC, Heliövaara M, Hoft NR, Hunter DJ, Jensen MK, Martin NG, Montgomery GW, Niu T, Payne TJ, Peltonen L, Pergadia ML, Rice JP, Sherva R, Spitz MR, Sun J, Wang JC, Weiss RB, Wheeler W, Witt SH, Yang BZ, Caporaso NE, Ehringer MA, Eisen T, Gapstur SM, Gelernter J, Houlston R, Kaprio J, Kendler KS, Kraft P, Leppert MF, Li MD, Madden PA, Nöthen MM, Pillai S, Rietschel M, Rujescu D, Schwartz A, Amos CI, Bierut LJ.

PLoS Genet. 2010 Aug 5;6(8). pii: e1001053. doi: 10.1371/journal.pgen.1001053.

PMID:
20700436
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Role of CHRNA5-A3 genetic Locus variants and developing drug for chronic obstructive pulmonary disease.

Lococo F, Cesario A, Petracca-Ciavarella L, Granone P, Russo P.

Curr Med Chem. 2012;19(34):5863-70.

PMID:
23061658
[PubMed - indexed for MEDLINE]
13.

Fine mapping of chromosome 15q25.1 lung cancer susceptibility in African-Americans.

Hansen HM, Xiao Y, Rice T, Bracci PM, Wrensch MR, Sison JD, Chang JS, Smirnov IV, Patoka J, Seldin MF, Quesenberry CP, Kelsey KT, Wiencke JK.

Hum Mol Genet. 2010 Sep 15;19(18):3652-61. doi: 10.1093/hmg/ddq268. Epub 2010 Jun 29.

PMID:
20587604
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Analysis of detailed phenotype profiles reveals CHRNA5-CHRNA3-CHRNB4 gene cluster association with several nicotine dependence traits.

Broms U, Wedenoja J, Largeau MR, Korhonen T, Pitkäniemi J, Keskitalo-Vuokko K, Häppölä A, Heikkilä KH, Heikkilä K, Ripatti S, Sarin AP, Salminen O, Paunio T, Pergadia ML, Madden PA, Kaprio J, Loukola A.

Nicotine Tob Res. 2012 Jun;14(6):720-33. doi: 10.1093/ntr/ntr283. Epub 2012 Jan 12.

PMID:
22241830
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes.

Saccone NL, Saccone SF, Hinrichs AL, Stitzel JA, Duan W, Pergadia ML, Agrawal A, Breslau N, Grucza RA, Hatsukami D, Johnson EO, Madden PA, Swan GE, Wang JC, Goate AM, Rice JP, Bierut LJ.

Am J Med Genet B Neuropsychiatr Genet. 2009 Jun 5;150B(4):453-66. doi: 10.1002/ajmg.b.30828.

PMID:
19259974
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Alpha-5 and -3 nicotinic receptor gene variants predict nicotine dependence but not cessation: findings from the COMMIT cohort.

Bousman CA, Rivard C, Haese JD, Ambrosone C, Hyland A.

Am J Med Genet B Neuropsychiatr Genet. 2012 Mar;159B(2):227-35. doi: 10.1002/ajmg.b.32019. Epub 2012 Jan 5.

PMID:
22223462
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Association of serum cotinine level with a cluster of three nicotinic acetylcholine receptor genes (CHRNA3/CHRNA5/CHRNB4) on chromosome 15.

Keskitalo K, Broms U, Heliövaara M, Ripatti S, Surakka I, Perola M, Pitkäniemi J, Peltonen L, Aromaa A, Kaprio J.

Hum Mol Genet. 2009 Oct 15;18(20):4007-12. doi: 10.1093/hmg/ddp322. Epub 2009 Jul 23.

PMID:
19628476
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking.

Stephens SH, Hartz SM, Hoft NR, Saccone NL, Corley RC, Hewitt JK, Hopfer CJ, Breslau N, Coon H, Chen X, Ducci F, Dueker N, Franceschini N, Frank J, Han Y, Hansel NN, Jiang C, Korhonen T, Lind PA, Liu J, Lyytikäinen LP, Michel M, Shaffer JR, Short SE, Sun J, Teumer A, Thompson JR, Vogelzangs N, Vink JM, Wenzlaff A, Wheeler W, Yang BZ, Aggen SH, Balmforth AJ, Baumeister SE, Beaty TH, Benjamin DJ, Bergen AW, Broms U, Cesarini D, Chatterjee N, Chen J, Cheng YC, Cichon S, Couper D, Cucca F, Dick D, Foroud T, Furberg H, Giegling I, Gillespie NA, Gu F, Hall AS, Hällfors J, Han S, Hartmann AM, Heikkilä K, Hickie IB, Hottenga JJ, Jousilahti P, Kaakinen M, Kähönen M, Koellinger PD, Kittner S, Konte B, Landi MT, Laatikainen T, Leppert M, Levy SM, Mathias RA, McNeil DW, Medland SE, Montgomery GW, Murray T, Nauck M, North KE, Paré PD, Pergadia M, Ruczinski I, Salomaa V, Viikari J, Willemsen G, Barnes KC, Boerwinkle E, Boomsma DI, Caporaso N, Edenberg HJ, Francks C, Gelernter J, Grabe HJ, Hops H, Jarvelin MR, Johannesson M, Kendler KS, Lehtimäki T, Magnusson PK, Marazita ML, Marchini J, Mitchell BD, Nöthen MM, Penninx BW, Raitakari O, Rietschel M, Rujescu D, Samani NJ, Schwartz AG, Shete S, Spitz M, Swan GE, Völzke H, Veijola J, Wei Q, Amos C, Cannon DS, Grucza R, Hatsukami D, Heath A, Johnson EO, Kaprio J, Madden P, Martin NG, Stevens VL, Weiss RB, Kraft P, Bierut LJ, Ehringer MA.

Genet Epidemiol. 2013 Dec;37(8):846-59. doi: 10.1002/gepi.21760. Epub 2013 Nov 1.

PMID:
24186853
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

From men to mice: CHRNA5/CHRNA3, smoking behavior and disease.

Ware JJ, van den Bree M, Munafò MR.

Nicotine Tob Res. 2012 Nov;14(11):1291-9. doi: 10.1093/ntr/nts106. Epub 2012 Apr 27. Review.

PMID:
22544838
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Ethnic- and gender-specific association of the nicotinic acetylcholine receptor alpha4 subunit gene (CHRNA4) with nicotine dependence.

Li MD, Beuten J, Ma JZ, Payne TJ, Lou XY, Garcia V, Duenes AS, Crews KM, Elston RC.

Hum Mol Genet. 2005 May 1;14(9):1211-9. Epub 2005 Mar 24.

PMID:
15790597
[PubMed - indexed for MEDLINE]
Free Article

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